PMAIP1

Gene Symbol PMAIP1
Entrez Gene 5366
Alt Symbol APR, NOXA
Species Human
Gene Type protein-coding
Description phorbol-12-myristate-13-acetate-induced protein 1
Other Description PMA-induced protein 1|adult T cell leukemia-derived PMA-responsive|immediate-early-response protein APR|protein Noxa
Swissprots Q8N589 Q13794 B2R4T7
Accessions Q13794 AK311943 BAG34884 BC013120 AAH13120 BC032663 AAH32663 BF667112 BM999509 D90070 BAA14111 JF432472 ADZ15689 NM_021127 NP_066950
Function Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1. Competes with BAK1 for binding to MCL1 and can displace BAK1 from its binding site on MCL1 (By similarity). Competes with BIM/BCL2L11 for binding to MCL1 and can displace BIM/BCL2L11 from its binding site on MCL1. {ECO:0000250, ECO:0000269|PubMed:10807576, ECO:0000269|PubMed:15694340, ECO:0000269|PubMed:15705586, ECO:0000269|PubMed:17374615, ECO:0000269|PubMed:17389404}.
Subcellular Location Mitochondrion {ECO:0000269|PubMed:15705586, ECO:0000269|PubMed:17374615}.
Tissue Specificity Highly expressed in adult T-cell leukemia cell line.
Top Pathways p53 signaling pathway, Viral carcinogenesis

SimpleChIP ® Human PMAIP1 Intron 1 Primers - 12558 from Cell Signaling Technology

Category ChIP Kit
Prices $102.00
Sizes 500 µl (250 PCR reactions)
SimpleChIP ® Human PMAIP1 Intron 1 Primers were tested on DNA isolated from cross-linked cells using the SimpleChIP ® Enzymatic Chromatin IP Kit (Magnetic Beads) #9003. Real-time PCR was performed in duplicate on a serial dilution of 2% total input DNA (20 ng, 4 ng, 0.8 ng, and 0.16 ng) using a real-time PCR detection system and SYBR ® Green reaction mix. The PCR amplification efficiency (E) and correlation coefficient (R 2 ) were calculated based on the corresponding threshold cycle (C T ) of each dilution sample during 40 cycles of real-time PCR (95°C denaturation for 15 sec, 65°C anneal/extension for 60 sec).

phorbol-12-myristate-13-acetate-induced protein 1, ELISA Kit - MBS9331244 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human PMAIP1 / NOXA ELISA Kit (Sandwich ELISA) - LS-F16886 from LifeSpan Bioscience

Category ELISA Kit
Prices $600.00
Sizes 1 plate
Sensitivity 78 pg/ml
Range 78-5000 pg/ml

Mouse PMAIP1 / NOXA ELISA Kit (Custom ELISA) - LS-F16888 from LifeSpan Bioscience

Category ELISA Kit
Prices $600.00
Sizes 1 plate
Sensitivity To be determined
Range 78-5000 pg/ml

Dog PMAIP1 / NOXA ELISA Kit (Custom ELISA) - LS-F16889 from LifeSpan Bioscience

Category ELISA Kit
Prices $700.00
Sizes 1 plate
Sensitivity To be determined
Range 78-5000 pg/ml

Rat PMAIP1 / NOXA ELISA Kit (Custom ELISA) - LS-F16887 from LifeSpan Bioscience

Category ELISA Kit
Prices $600.00
Sizes 1 plate
Sensitivity To be determined
Range 78-5000 pg/ml

PMAIP1 - EKH2992 from Nordic BioSite

Sensitivity 46.9pg/ml
Range 78-5000pg/ml

PMAIP1 ELISA Kit (Human) (OKEH02296) - OKEH02296 from Aviva Systems Biology

Category ELISA Kit
Prices $420.00
Sizes 96 wells
Sensitivity < 31 pg/mL
Range 78 - 5,000 pg/mL

Human PMAIP1 ELISA Kit - E028857 from Biobool

Category ELISA Kit
Sensitivity <46.9pg/ml

Human Phorbol-12-myristate-13-acetate-induced protein 1 ELISA Kit - EK3195 from Signalway Antibody

Category ELISA Kit
Prices $599.00
Sizes 1x96t
Sensitivity less than 31pg/ml
Range 78-5000 pg/mL

anti-NOXA antibody - ARG56838 from Arigo Biolaboratories

Category ELISA Kit

anti-NOXA antibody - ARG64942 from Arigo Biolaboratories

Category ELISA Kit

Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1), ELISA Kit - MBS9348624 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1), ELISA Kit - MBS9356707 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1), ELISA Kit - MBS9346478 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1), ELISA Kit - MBS9351791 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1), ELISA Kit - MBS9354191 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1), ELISA Kit - MBS9352776 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1), ELISA Kit - MBS9362777 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1), ELISA Kit - MBS9344706 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1), ELISA Kit - MBS9367786 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1), ELISA Kit - MBS9363815 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1), ELISA Kit - MBS9365054 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1), ELISA Kit - MBS9361918 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1), ELISA Kit - MBS9367838 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
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