GARS

Gene Symbol GARS
Entrez Gene 2617
Alt Symbol CMT2D, DSMAV, GlyRS, HMN5, SMAD1
Species Human
Gene Type protein-coding
Description glycyl-tRNA synthetase
Other Description AP-4-A synthetase|Charcot-Marie-Tooth neuropathy 2D|Charcot-Marie-Tooth neuropathy, neuronal type, D|diadenosine tetraphosphate synthetase|glycine tRNA ligase|glycine--tRNA ligase
Swissprots Q969Y1 B4DIA0 P41250 B3KQA2
Accessions AAC71652 AAS00367 EAL24449 EAW93960 EAW93961 P41250 AA772440 AK074524 BAG51964 AK295490 BAG58412 AK310351 BC000065 BC007722 AAH07722 BC007755 AAH07755 D30658 BAA06338 DQ892773 ABM83699 DQ896021 ABM87020 U09510 AAA86443 U09587 AAA57001 XM_006715686 XP_006715749 NM_002047 NP_002038
Function Catalyzes the attachment of glycine to tRNA(Gly). Is also able produce diadenosine tetraphosphate (Ap4A), a universal pleiotropic signaling molecule needed for cell regulation pathways, by direct condensation of 2 ATPs. {ECO:0000269|PubMed:19710017}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:9524218}. Mitochondrion {ECO:0000269|PubMed:9524218}.
Tissue Specificity Widely expressed, including brain and spinal cord. {ECO:0000269|PubMed:12690580}.
Top Pathways Aminoacyl-tRNA biosynthesis

GlyRS (F-5) - sc-365442 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
GlyRS (F-5): sc-365442. Western blot analysis of GlyRS expression in non-transfected 293T: sc-117752 (A), mouse GlyRS transfected 293T: sc-120534 (B) and Jurkat (C) whole cell lysates.

GlyRS (A-6) - sc-373904 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
GlyRS (A-6): sc-373904. Western blot analysis of GlyRS expression in non-transfected 293T: sc-117752 (A), mouse GlyRS transfected 293T: sc-120534 (B) and Jurkat (C) whole cell lysates.

GlyRS (D-10) - sc-365311 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
GlyRS (D-10): sc-365311. Western blot analysis of GlyRS expression in non-transfected 293T: sc-117752 (A), mouse GlyRS transfected 293T: sc-120534 (B), HeLa (C) and Jurkat (D) whole cell lysates.

GlyRS (Y-18) - sc-69486 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
GlyRS (Y-18): sc-69486. Western blot analysis of GlyRS expression in Jurkat whole cell lysate.

GlyRS (H-1) - sc-271778 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
GlyRS (H-1): sc-271778. Western blot analysis of GlyRS expression in non-transfected 293T: sc-117752 (A), mouse GlyRS transfected 293T: sc-120534 (B), HeLa (C) and Jurkat (D) whole cell lysates.

GlyRS (H-300) - sc-98614 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
GlyRS (H-300): sc-98614. Western blot analysis of GlyRS expression in Jurkat whole cell lysate.

GlyRS (T-17) - sc-69485 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
GlyRS (T-17): sc-69485. Western blot analysis of GlyRS expression in Jurkat whole cell lysate.

Smad1/5/8 (N-18)-R - sc-6031-R from Santa Cruz Biotechnology

Prices $61.00
Sizes 100 µg/0.5 ml
Host Rabbit
Clonality Polyclonal
Smad1/5/8 (N-18): sc-6031. Western blot analysis of Smad1/5/8 expression in NIH/3T3 whole cell lysate.

Anti-GARS antibody - ab42905 from Abcam

Prices $394.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-GARS antibody (ab42905) at 1/5000 dilution + whole cell lysate prepared from HEK293 cells at 50 µg/mlSecondaryGoat anti-rabbit IgG (H+L) at 1/10000 dilution

Anti-GARS antibody - ab196496 from Abcam

Prices $378.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-GARS antibody (ab196496) at 1/500 dilutionLane 1 : Jurkat cell lysateLane 2 : 293T cell lysateLane 3 : U87 cell lysateLane 4 : Raji cell lysateLane 5 : M21 cell lysateLane 6 : 22RV-1 cell lysateLane 7 : HT29 cell lysateLane 8 : mouase brain tissue lysateLane 9 : mouse spinal cord tissue lysate

Anti-GARS antibody - ab153852 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-GARS antibody (ab153852) at 1/1000 dilutionLane 1 : 293T whole cell lysateLane 2 : A431 whole cell lysateLane 3 : Raji whole cell lysateLysates/proteins at 30 µg per lane.

Anti-GARS antibody - ab89522 from Abcam

Prices $376.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-GARS antibody (ab89522) at 1 µg/ml + human placenta tissue lysate at 50 µg

Anti-GARS antibody [AT4E10] - ab201703 from Abcam

Prices $359.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone AT4E10
All lanes : Anti-GARS antibody [AT4E10] (ab201703) at 1/500 dilutionLane 1 : HeLa cell lysateLane 2 : 293T cell lysateLysates/proteins at 40 µg per lane.developed using the ECL technique

Anti-GARS antibody [EPR7157] - ab125008 from Abcam

Prices $379.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR7157
All lanes : Anti-GARS antibody [EPR7157] (ab125008) at 1/1000 dilutionLane 1 : Jurkat cell lysateLane 2 : Hela cell lysateLane 3 : U87-MG cell lysateLane 4 : 293T cell lysateLane 5 : C6 cell lysateLane 6 : RAW 264.7 cell lysateLane 7 : Neuro-2a cell lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-GARS antibody - C-terminal - ab82848 from Abcam

Prices $376.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-GARS antibody - C-terminal (ab82848) at 1/50 dilution + Ramos cell line lysates at 35 µg

Anti-GARS / Glycyl tRNA Synthetase Antibody - LS-C310454 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-GARS / Glycyl tRNA Synthetase Antibody - LS-C308050 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-GART / GARS Antibody - LS-C341618 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-GARS / Glycyl tRNA Synthetase Antibody (aa575-624) - LS-C112248 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
GARS antibody LS-C112248 Western blot of MCF7 cell lysate.

Anti-GARS / Glycyl tRNA Synthetase Antibody (clone 4H8) - LS-C340643 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 4H8
IHC of paraffin-embedded Carcinoma of Human kidney tissue using anti-GARS mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).

Anti-GARS / Glycyl tRNA Synthetase Antibody (clone 6C5) - LS-C339485 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 6C5
IHC of paraffin-embedded Carcinoma of Human kidney tissue using anti-GARS mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).

Anti-GARS / Glycyl tRNA Synthetase Antibody (C-Terminus, clone EPR7157) - LS-C139017 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR7157
IHC of paraffin-embedded colon tissue using anti-GARS antibody.

Anti-GARS / Glycyl tRNA Synthetase Antibody - LS-C335569 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence analysis of MCF-7 cell using GARS antibody. Blue: DAPI for nuclear staining.

Anti-GARS / Glycyl tRNA Synthetase Antibody (clone 4G4) - LS-C339527 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 4G4
IHC of paraffin-embedded Human endometrium tissue using anti-GARS mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).

Anti-GARS / Glycyl tRNA Synthetase Antibody (aa706-739) IHC-plus™ - LS-B9126 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)
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