SREBF2

Gene Symbol	SREBF2
Entrez Gene	6721
Alt Symbol	SREBP-2, SREBP2, bHLHd2
Species	Human
Gene Type	protein-coding
Description	sterol regulatory element binding transcription factor 2
Other Description	class D basic helix-loop-helix protein 2|sterol regulatory element-binding protein 2|sterol regulatory element-binding transcription factor 2
Swissprots	Q12772 Q6GTH7 Q86V36 Q9UH04 Q05BD5
Accessions	BAC57590 EAW60469 EAW60470 EAW60471 Q12772 AA035591 AK299914 BAG61752 AL834221 CAD38902 BC051385 AAH51385 BC051799 AAH51799 BC056158 AAH56158 CT841522 CAJ86452 CU013184 CAK54615 CU013472 CAK54914 U02031 AAA50746 XM_006724310 XP_006724373 XM_011530347 XP_011528649 NM_004599 NP_004590 NR_103834
Function	Transcriptional activator required for lipid homeostasis. Regulates transcription of the LDL receptor gene as well as the cholesterol and to a lesser degree the fatty acid synthesis pathway (By similarity). Binds the sterol regulatory element 1 (SRE-1) (5'-ATCACCCCAC-3') found in the flanking region of the LDRL and HMG-CoA synthase genes. {ECO:0000250}.
Subcellular Location	Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Cytoplasmic vesicle, COPII-coated vesicle membrane; Multi-pass membrane protein. Note=Moves from the endoplasmic reticulum to the Golgi in the absence of sterols.
Tissue Specificity	Ubiquitously expressed in adult and fetal tissues.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human SREBP2 peptide - ab72855 from Abcam Category Peptide

Human SREBP2 protein fragment - ab114215 from Abcam Category Protein Source Wheat germ Species Human

Rat SREBP2 peptide - ab39821 from Abcam Category Peptide Species Rat

SREBP2 peptide - ab174740 from Abcam Category Peptide

SREBF2 / SREBP2 Antibody Blocking Peptide - LS-E394 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SREBF2 / SREBP2 Antibody Blocking Peptide - LS-E10804 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SREBF2 / SREBP2 Antibody Blocking Peptide - LS-E10649 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human SREBP2 Protein - H00006721-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

SREBF2-Antibody-Center-Blocking-peptide - BP10673c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

SREBF2 Protein Lysate (APL10944) - APL10944 from Aviva Systems Biology Category Protein Prices $219.00 Sizes 200 µg

SREBF2 Blocking Peptide - 33R-6977 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

SREBF2 / SREBP2 - H00006721-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

SREBF2 / SREBP2 - H00006721-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

SREBF2 Peptide - 7855P from ProSci Category Peptide Species Human

SREBF2 fusion protein - ag5967 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

SREBF2 fusion protein - Ag6066 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human SREBF2 - SREBF2-31395TH from Creative Biomart Category Protein Source Wheat germ

SREBP2 Recombinant Protein Antigen - NBP1-89978PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

SREBF2 Peptide, Human - M34GP15142H from Creative Peptides Category Peptide Source Synthetic. Species Human

SREBF2 Protein Lysate - orb333573 from Biorbyt Category Protein Prices $400.00 Sizes 200 μg Species Human

Sterol regulatory element-binding protein 2 (SREBF2), Recombinant Protein - MBS7074203 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Sterol regulatory element-binding protein 2 (SREBF2), Recombinant Protein - MBS7030456 from MyBioSource Category Protein Prices $1,285.00, $2,270.00, $3,480.00 Sizes 10 µg, 50 µg, 100 µg Source E Coli Species Human

SREBP2 Recombinant Protein Antigen - NBP2-58133PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

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