IL21

Gene Symbol	IL21
Entrez Gene	59067
Alt Symbol	CVID11, IL-21, Za11
Species	Human
Gene Type	protein-coding
Description	interleukin 21
Other Description	interleukin-21|interleukin-21 isoform
Swissprots	A5J0L4 Q9HBE4
Accessions	AAU88182 CAI94500 CAJ47524 CAL81203 CAN87399 CAS03522 CAV33288 CBE74752 CBI70418 CBI85469 CBI85472 CBL93962 CCA63962 EAX05226 Q9HBE4 AF254069 AAG29348 BC066258 AAH66258 BC066259 AAH66259 BC066260 AAH66260 BC066261 AAH66261 BC066262 AAH66262 BC069124 AAH69124 CD559460 CD559613 DQ645417 ABG36529 HQ447458 ADQ31944 NM_001207006 NP_001193935 NM_021803 NP_068575
Function	Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells (By similarity). May play a role in proliferation and maturation of natural killer (NK) cells in synergy with IL15. May regulate proliferation of mature B- and T-cells in response to activating stimuli. In synergy with IL15 and IL18 stimulates interferon gamma production in T-cells and NK cells. During T-cell mediated immune response may inhibit dendritic cells (DC) activation and maturation. {ECO:0000250, ECO:0000269|PubMed:11081504, ECO:0000269|PubMed:15178704}.
Subcellular Location	Secreted {ECO:0000269|PubMed:11081504}.
Tissue Specificity	Expressed in activated CD4-positive T-cells but not in CD8-positive T-cells, B-cells, or monocytes. {ECO:0000269|PubMed:11081504}.
Top Pathways	Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Inflammatory bowel disease (IBD)

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

IL-21 (Interleukin-21) Human ELISA Kit - ab119542 from Abcam Category ELISA Kit Prices $489.00 Sizes 1 x 96 tests Sensitivity 20 pg/ml Range 78 pg/ml - 5000 pg/ml

Mouse IL21 ELISA Kit (Sandwich ELISA) - LS-F2682 from LifeSpan Bioscience Category ELISA Kit Prices $570.00 Sizes 1 plate Sensitivity 10 pg/ml Range 8.192-800 pg/ml

Rat IL21 ELISA Kit (Sandwich ELISA) - LS-F4987 from LifeSpan Bioscience Category ELISA Kit Prices $740.00 Sizes 1 plate Sensitivity 5.8 pg/ml Range 8.192-800 pg/ml

Human IL21 ELISA Kit (Sandwich ELISA) - LS-F4908 from LifeSpan Bioscience Category ELISA Kit Prices $690.00 Sizes 1 plate Sensitivity 6.1 pg/ml Range 8.192-800 pg/ml

Mouse IL21 ELISA Kit (Sandwich ELISA) - LS-F5281 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity 6.1 pg/ml Range 8.192-800 pg/ml

Mouse IL21 ELISA Kit (Sandwich ELISA) - LS-F259 from LifeSpan Bioscience Category ELISA Kit Prices $460.00, $840.00, $1,960.00 Sizes 1 plate, 2 plate, 5 plate Sensitivity 8.192 pg/ml Range 8.192-800 pg/ml

Human IL21 ELISA Kit (Sandwich ELISA) - LS-F958 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate Range 8.192-800 pg/ml

Mouse IL21 ELISA Kit (Sandwich ELISA) - LS-F972 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate Range 8.192-800 pg/ml

Human IL21 / Interleukin-21 ELISA Kit - RAB0695 from Sigma-Aldrich Category ELISA Kit Prices $479.00 Sizes 1 kt

Mouse IL-21 DuoSet ELISA - DY594 from R&D Systems Category ELISA Kit Prices $249.00, $649.00 Sizes 1 kit (for 5 Plates), 1 kit (for 15 Plates) Range 62.50 - 4,000 pg/mL

Mouse IL-21 DuoSet, 5 Plate - DY594-05 from R&D Systems Category ELISA Kit

Human IL21 ELISA kit - 55R-2183 from Fitzgerald Category ELISA Kit Prices $545.00 Sizes 96 tests

Rat IL21 ELISA kit - 55R-2166 from Fitzgerald Category ELISA Kit Prices $545.00 Sizes 96 tests

IL-21 ELISA Kit (Human) : 96 Wells (OKAG00034) - OKAG00034 from Aviva Systems Biology Category ELISA Kit Prices $390.00 Sizes 96 wells Sensitivity 46 pg/mL Range 46-3,000 pg/mL

Human Interleukin 21 ELISA Kit - abx052275 from Abbexa Category ELISA Kit

Human Interleukin 21 ELISA Kit - abx152029 from Abbexa Category ELISA Kit Sensitivity 6.0 pg/ml Range 15.625 pg/ml - 1000 pg/ml

Interleukin 21, IL-21, Human, ELISA Kit - E-EL-H2450 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 37.5 Range 62.5-4000pg/mL

Interleukin 21 (IL21), Human, ELISA Kit - SEB688Hu from ARP American Research Products Category ELISA Kit Prices $685.00 Sizes 96 t Sensitivity 6.2pg/mL Range 15.6-1,000pg/mL

Interleukin 21, Human, ELISA Kit - E01I0028 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t Sensitivity 1.0pg/ml Range 50-1000pg/ml

Interleukin 21, IL-21, Human, ELISA Kit - CSB-E11707h from ARP American Research Products Category ELISA Kit Prices $366.00, $496.00, $497.00, $499.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 0.78 pg/ml Range 3.12 pg/ml-200 pg/ml

Interleukin 22 (IL-22), Human, ELISA Kit - CSB-E13418h from ARP American Research Products Category ELISA Kit Prices $450.00, $595.00, $596.00, $599.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 3.9 pg/ml Range 15.6 pg/ml-1000 pg/ml

Interleukin-21, IL21, Human, ELISA Kit - E1688h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 15.6-1000 pg/mL

Interleukin 21, IL-21, Mouse, ELISA Kit - E-EL-M1273 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 18.75 Range 31.25-2000pg/mL

Interleukin 21, IL-21, Rat, ELISA Kit - E-EL-R0568 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 9.375 Range 15.625-1000pg/mL

Interleukin 21 (IL21), Human, CLIA Kit - SCB688Hu from ARP American Research Products Category CLIA Kit Prices $840.00 Sizes 96 t Sensitivity 4.1pg/mL Range 15.6-1,000pg/mL

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