SPOPL

Gene Symbol	SPOPL
Entrez Gene	339745
Alt Symbol	BTBD33
Species	Human
Gene Type	protein-coding
Description	speckle-type POZ protein-like
Other Description	HIB homolog 2|roadkill homolog 2
Swissprots	Q6IQ16
Accessions	EAX11609 Q6IQ16 AA737682 AK094583 AK293850 BAG57248 BC071613 AAH71613 BX538143 CD643025 CN315400 HQ447434 ADQ31920 XM_005263655 XP_005263712 XM_005263656 XP_005263713 XM_005263657 XP_005263714 XM_011511074 XP_011509376 NM_001001664 NP_001001664
Function	Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins, but with relatively low efficiency. Cullin-RING-based BCR (BTB-CUL3- RBX1) E3 ubiquitin-protein ligase complexes containing homodimeric SPOPL or the heterodimer formed by SPOP and SPOPL are less efficient than ubiquitin ligase complexes containing only SPOP. May function to down-regulate the activity of cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complexes that contain SPOP. {ECO:0000269|PubMed:22632832}.
Subcellular Location	Nucleus {ECO:0000250}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human-SPOPL-cDNA-Clone - DC08885 from Abgent, a WuXi AppTec company Prices $529.20 Sizes 10 µg Species Human Accession BC071613

SPOPL - MBS1269633 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC071613

human SPOPL ORF clone - CDCH085530 from Creative Biomart Species Human Accession NM_001001664

human SPOPL ORF clone - CDCH085531 from Creative Biomart Species Human Accession NM_001001664

Human SPOPL ORF Clone(NM_001001664.2) - CDCL176912 from Creative Biomart Species Human Accession NM_001001664.2

Human SPOPL Gene ORF cDNA clone in cloning vector - HG15394-G from Sino Biological Species Human

Human SPOPL Gene ORF cDNA clone expression plasmid, N-HA tag - HG15394-NY from Sino Biological Species Human

Human SPOPL Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG15394-ACG from Sino Biological Species Human

Human SPOPL Gene ORF cDNA clone expression plasmid, C-Flag tag - HG15394-CF from Sino Biological Species Human

Human SPOPL Gene ORF cDNA clone expression plasmid, N-His tag - HG15394-NH from Sino Biological Species Human

Human SPOPL Gene ORF cDNA clone expression plasmid, N-Myc tag - HG15394-NM from Sino Biological Species Human

Human SPOPL Gene ORF cDNA clone expression plasmid, C-Myc tag - HG15394-CM from Sino Biological Species Human

Human SPOPL Gene ORF cDNA clone expression plasmid, C-His tag - HG15394-CH from Sino Biological Species Human

Human SPOPL Gene ORF cDNA clone expression plasmid - HG15394-UT from Sino Biological Species Human

Human SPOPL Gene ORF cDNA clone expression plasmid, C-HA tag - HG15394-CY from Sino Biological Species Human

Human SPOPL Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG15394-ANG from Sino Biological Species Human

Human SPOPL Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG15394-ACR from Sino Biological Species Human

Human SPOPL Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG15394-ANR from Sino Biological Species Human

Human SPOPL Gene ORF cDNA clone expression plasmid, N-Flag tag - HG15394-NF from Sino Biological Species Human

Human SPOPL ORF Clone (BC071613) - CDCS406096 from Creative biogene Species Human Accession Q6IQ16

Human SPOPL ORF clone (BC071613) - CDCB158203 from Creative biogene Species Human

Search more