SPOPL

Gene Symbol SPOPL
Entrez Gene 339745
Alt Symbol BTBD33
Species Human
Gene Type protein-coding
Description speckle-type POZ protein-like
Other Description HIB homolog 2|roadkill homolog 2
Swissprots Q6IQ16
Accessions EAX11609 Q6IQ16 AA737682 AK094583 AK293850 BAG57248 BC071613 AAH71613 BX538143 CD643025 CN315400 HQ447434 ADQ31920 XM_005263655 XP_005263712 XM_005263656 XP_005263713 XM_005263657 XP_005263714 XM_011511074 XP_011509376 NM_001001664 NP_001001664
Function Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins, but with relatively low efficiency. Cullin-RING-based BCR (BTB-CUL3- RBX1) E3 ubiquitin-protein ligase complexes containing homodimeric SPOPL or the heterodimer formed by SPOP and SPOPL are less efficient than ubiquitin ligase complexes containing only SPOP. May function to down-regulate the activity of cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complexes that contain SPOP. {ECO:0000269|PubMed:22632832}.
Subcellular Location Nucleus {ECO:0000250}.

SPOPL CRISPR/Cas9 KO Plasmid (h) - sc-406382 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SPOPL HDR Plasmid (h) - sc-406382-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SPOPL Double Nickase Plasmid (h) - sc-406382-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SPOPL Double Nickase Plasmid (h2) - sc-406382-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SPOPL CRISPR Activation Plasmid (h) - sc-406382-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SPOPL CRISPR Activation Plasmid (h2) - sc-406382-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SPOPL Lentiviral Activation Particles (h) - sc-406382-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SPOPL Lentiviral Activation Particles (h2) - sc-406382-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SPOPL siRNA (h) - sc-94798 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SPOPL shRNA Plasmid (h) - sc-94798-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SPOPL shRNA (h) Lentiviral Particles - sc-94798-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU144331 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN20508 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20508 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

SPOPL siRNA (Human) - CRJ7305 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SPOPL - MBS8213473 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human SPOPL (NM_001001664.2) - SHH417100 from Creative biogene

Category siRNA
Species Reactivities Human

SPOPL shRNA Plasmid (Human) - CHJ7305 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
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