SPOPL

Gene Symbol	SPOPL
Entrez Gene	339745
Alt Symbol	BTBD33
Species	Human
Gene Type	protein-coding
Description	speckle-type POZ protein-like
Other Description	HIB homolog 2|roadkill homolog 2
Swissprots	Q6IQ16
Accessions	EAX11609 Q6IQ16 AA737682 AK094583 AK293850 BAG57248 BC071613 AAH71613 BX538143 CD643025 CN315400 HQ447434 ADQ31920 XM_005263655 XP_005263712 XM_005263656 XP_005263713 XM_005263657 XP_005263714 XM_011511074 XP_011509376 NM_001001664 NP_001001664
Function	Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins, but with relatively low efficiency. Cullin-RING-based BCR (BTB-CUL3- RBX1) E3 ubiquitin-protein ligase complexes containing homodimeric SPOPL or the heterodimer formed by SPOP and SPOPL are less efficient than ubiquitin ligase complexes containing only SPOP. May function to down-regulate the activity of cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complexes that contain SPOP. {ECO:0000269|PubMed:22632832}.
Subcellular Location	Nucleus {ECO:0000250}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human SPOPL full length protein - ab166270 from Abcam Category Protein Source Wheat germ Species Human

SPOPL Antibody Blocking Peptide - LS-E1925 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SPOPL Antibody Blocking Peptide - LS-E18173 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SPOPL Antibody Blocking Peptide - LS-E18174 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human SPOPL Protein - H00339745-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

SPOPL-Antibody-Center-Blocking-peptide - BP12768c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

SPOPL Blocking Peptide - 33R-4395 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

SPOPL Blocking Peptide - 33R-9986 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

SPOPL - H00339745-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

SPOPL - H00339745-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

SPOPL fusion protein - Ag11974 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

SPOPL fusion protein - Ag11951 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human SPOPL, His-tagged - SPOPL-2930H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human Speckle-type POZ protein-like(SPOPL) - CSB-YP022602HU CSB-EP022602HU CSB-BP022602HU CSB-MP022602HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

SPOPL Recombinant Protein Antigen - NBP1-86315PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

SPOPL Peptide, Human - M34GP15081H from Creative Peptides Category Peptide Source Synthetic. Species Human

Speckle-type POZ protein-like (SPOPL), Recombinant Protein - MBS1356539 from MyBioSource Category Protein Prices $1,160.00, $1,160.00, $1,395.00, $1,395.00, $1,860.00, $1,860.00, $2,325.00, $2,325.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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