PCGF6

Gene Symbol	PCGF6
Entrez Gene	84108
Alt Symbol	MBLR, RNF134
Species	Human
Gene Type	protein-coding
Description	polycomb group ring finger 6
Other Description	Mel18 and Bmi1-like RING finger protein|polycomb group RING finger protein 6|ring finger protein 134
Swissprots	Q5SYD6 A8K3R4 Q96SJ1 Q96ID9 Q5SYD1 Q9BYE7
Accessions	EAW49647 EAW49648 EAW49649 EAW49650 EAW49651 EAW49652 Q9BYE7 AB047006 BAB40779 AK027885 AK290679 BAF83368 AK309105 BC007602 AAH07602 BC010235 AAH10235 EU446621 ABZ92150 EU447006 ABZ92535 XM_005270213 XP_005270270 XM_011540261 XP_011538563 NM_001011663 NP_001011663 NM_032154 NP_115530
Function	Transcriptional repressor. May modulate the levels of histone H3K4Me3 by activating KDM5D histone demethylase. Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. {ECO:0000269|PubMed:12167161, ECO:0000269|PubMed:17320162}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:12167161, ECO:0000269|PubMed:21282530}.
Tissue Specificity	Ubiquitous.
Top Pathways	Signaling pathways regulating pluripotency of stem cells

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human RING6a full length protein - ab132525 from Abcam Category Protein Source Wheat germ Species Human

Human RING6a full length protein - ab198485 from Abcam Category Protein Source Baculovirus infected sf9 cells Species Human

Human RING6a peptide - ab48223 from Abcam Category Peptide

Human RING6a protein fragment - ab164499 from Abcam Category Protein Source Wheat germ Species Human

PCGF6 Antibody Blocking Peptide - LS-E6207 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PCGF6 Antibody Blocking Peptide - LS-E15948 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human PCGF6 Protein - H00084108-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human PCGF6 Protein - H00084108-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

PCGF6-Antibody-Center-Blocking-Peptide - BP18850c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

PCGF6 Blocking Peptide - 33R-9248 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

PCGF6 / RNF134 - H00084108-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

PCGF6 / RNF134 - H00084108-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

PCGF6 / RNF134 - H00084108-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

PCGF6 / RNF134 - H00084108-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

PCGF6 fusion protein - Ag21124 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET30a Species Human

PCGF6 fusion protein - ag13611 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human Polycomb group RING finger protein 6(PCGF6) - CSB-YP871612HU CSB-EP871612HU CSB-BP871612HU CSB-MP871612HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Polycomb group RING finger protein 6 (PCGF6), Recombinant Protein - MBS1435240 from MyBioSource Category Protein Prices $1,115.00, $1,115.00, $1,345.00, $1,345.00, $1,765.00, $1,765.00, $2,230.00, $2,230.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

PCGF6 Recombinant Protein Antigen - NBP2-49115PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

PCGF6-Blocking-Peptide-C-term - BP20945c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

PCGF6-Blocking-Peptide-Center - BP21285c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

PCGF6 Peptide, Human - M34GP11442H from Creative Peptides Category Peptide Source Synthetic. Species Human

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