PCGF6

Gene Symbol PCGF6
Entrez Gene 84108
Alt Symbol MBLR, RNF134
Species Human
Gene Type protein-coding
Description polycomb group ring finger 6
Other Description Mel18 and Bmi1-like RING finger protein|polycomb group RING finger protein 6|ring finger protein 134
Swissprots Q5SYD6 A8K3R4 Q96SJ1 Q96ID9 Q5SYD1 Q9BYE7
Accessions EAW49647 EAW49648 EAW49649 EAW49650 EAW49651 EAW49652 Q9BYE7 AB047006 BAB40779 AK027885 AK290679 BAF83368 AK309105 BC007602 AAH07602 BC010235 AAH10235 EU446621 ABZ92150 EU447006 ABZ92535 XM_005270213 XP_005270270 XM_011540261 XP_011538563 NM_001011663 NP_001011663 NM_032154 NP_115530
Function Transcriptional repressor. May modulate the levels of histone H3K4Me3 by activating KDM5D histone demethylase. Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. {ECO:0000269|PubMed:12167161, ECO:0000269|PubMed:17320162}.
Subcellular Location Nucleus {ECO:0000269|PubMed:12167161, ECO:0000269|PubMed:21282530}.
Tissue Specificity Ubiquitous.
Top Pathways Signaling pathways regulating pluripotency of stem cells

PCGF6 (E-15) - sc-160649 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
PCGF6 (E-15): sc-160649. Western blot analysis of PCGF6 expression in mouse testis tissue extract (A) and F9 whole cell lysate (B).

PCGF6 (H-93) - sc-367209 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
PCGF6 (H-93): sc-367209. Western blot analysis of PCGF6 expression in NCI-H929 whole cell lysate.

Anti-RING6a antibody - ab192395 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-RING6a antibody - ab48010 from Abcam

Prices $242.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-RING6a antibody - ab102059 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-RING6a antibody (ab102059) at 1 µg/ml + NCI-H226 cell lysate at 10 µg

Anti-RING6a antibody - ab169113 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-RING6a antibody (ab169113) at 1 µg/mlLane 1 : RING6a transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 15 µl per lane.developed using the ECL technique

Anti-PCGF6 Antibody (aa190-217) - LS-C158553 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
PCGF6 Antibody western blot of NCI-H292,rat liver,stomach and testis cell line lysates (35 ug/lane). The PCGF6 antibody detected the PCGF6 protein (arrow).

Anti-PCGF6 Antibody (aa261-295) - LS-C344516 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of lysate from human kidney tissue with PCGF6 Antibody. Antibody was diluted at 1:1000. A goat anti-rabbit IgG H&L (HRP) at 1:10000 dilution was used as the secondary antibody. Lysate at 20 ug.

Anti-PCGF6 Antibody - LS-C155110 from LifeSpan Bioscience

Prices $245.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-PCGF6 Antibody (aa190-217, AP) - LS-C223598 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PCGF6 Antibody (aa190-217, APC) - LS-C223599 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PCGF6 Antibody (aa190-217, Biotin) - LS-C223600 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PCGF6 Antibody (aa190-217, FITC) - LS-C223601 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PCGF6 Antibody (aa190-217, PE) - LS-C223603 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PCGF6 Antibody (aa190-217, Azide-free, HRP) - LS-C223602 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PCGF6 Antibody (aa189-217) - LS-C323857 from LifeSpan Bioscience

Prices $435.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PCGF6 Antibody - LS-C341850 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PCGF6 Antibody (aa179-228) - LS-C116232 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
PCGF6 antibody LS-C116232 Western blot of NCI-H226 cell lysate.

Anti-PCGF6 Antibody - LS-C346095 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence blot of HeLa cell using PCGF6 antibody. Blue: DAPI for nuclear staining.

PCGF6 Antibody - NBP1-55372 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal

PCGF6 Antibody - H00084108-B01P from Novus Biologicals

Prices $349.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: PCGF6 Antibody [H00084108-B01P] - analysis of PCGF6 expression in transfected 293T cell line by PCGF6 MaxPab polyclonal antibody. Lane 1: PCGF6 transfected lysate (30.47 KDa). Lane 2: Non-transfected lysate.

PCGF6 Antibody - NBP1-31986 from Novus Biologicals

Host Rabbit
Clonality Polyclonal

PCGF6 Antibody (2B8) - H00084108-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2B8

Anti-PCGF6 antibody produced in rabbit - SAB2105508 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-PCGF6: <B>Cat. No. SAB2105508</B>: PCGF6 in NCI-H226 cell lysates with PCGF6 antibody at 1.0 μg/mL.

Monoclonal Anti-PCGF6 antibody produced in mouse - SAB1403393 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2B8
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