IL1R1

Gene Symbol	IL1R1
Entrez Gene	3554
Alt Symbol	CD121A, D2S1473, IL-1R-alpha, IL1R, IL1RA, P80
Species	Human
Gene Type	protein-coding
Description	interleukin 1 receptor, type I
Other Description	CD121 antigen-like family member A|IL-1R-1|IL-1RT-1|IL-1RT1|interleukin 1 receptor alpha, type I|interleukin-1 receptor alpha|interleukin-1 receptor type 1|interleukin-1 receptor type I
Swissprots	Q587I7 P14778
Accessions	AAM88423 AAX81988 CAD57171 CCF76934 EAX01799 P14778 AK026803 AK314433 AL548240 BC067506 AAH67506 BC067507 AAH67507 BC067508 AAH67508 BC075062 AAH75062 BC075063 AAH75063 BE144272 BQ021163 DA861783 HY092388 M27492 AAA59137 X16896 CAA34773 XM_005263929 XP_005263986 XM_005263930 XP_005263987 XM_005263931 XP_005263988 XM_005263932 XP_005263989 XM_005263933 XP_005263990 XM_005263934 XP_005263991 XM_011511114 XP_011509416 XM_011511115 XP_011509417 XM_011511116 XP_011509418 XM_011511117 XP_011509419 XM_011511118 XP_011509420 XM_011511119 XP_011509421 XM_011511120 XP_011509422 NM_000877 NP_000868 NM_001288706 NP_001275635
Function	Receptor for IL1A, IL1B and IL1RN. After binding to interleukin-1 associates with the corecptor IL1RAP to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B, MAPK and other pathways. Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits. Binds ligands with comparable affinity and binding of antagonist IL1RN prevents association with IL1RAP to form a signaling complex. {ECO:0000269|PubMed:10671496}.
Subcellular Location	Membrane {ECO:0000269|PubMed:8142597}; Single-pass type I membrane protein {ECO:0000269|PubMed:8142597}. Cell membrane {ECO:0000305|PubMed:8142597}. Secreted {ECO:0000269|PubMed:8142597}.
Top Pathways	Amoebiasis, Inflammatory mediator regulation of TRP channels, HTLV-I infection, Osteoclast differentiation, Cytokine-cytokine receptor interaction

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human IL1R1 ELISA Kit (Sandwich ELISA) - LS-F2464 from LifeSpan Bioscience Category ELISA Kit Prices $530.00 Sizes 1 plate Sensitivity 10 pg/ml Range 125-8000 pg/ml

Human IL1R1 ELISA Kit (Sandwich ELISA) - LS-F5097 from LifeSpan Bioscience Category ELISA Kit Prices $650.00 Sizes 1 plate Sensitivity 0.049 ng/ml Range 125-8000 pg/ml

Mouse IL1R1 ELISA Kit (Sandwich ELISA) - LS-F5540 from LifeSpan Bioscience Category ELISA Kit Prices $670.00 Sizes 1 plate Sensitivity 14.8 pg/ml Range 125-8000 pg/ml

Human IL1R1 ELISA Kit (Sandwich ELISA) - LS-F991 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate Range 125-8000 pg/ml

Human IL1R1 ELISA Kit (Sandwich ELISA) - LS-F11763 from LifeSpan Bioscience Category ELISA Kit Prices $530.00 Sizes 1 plate Sensitivity 0.156 Range 125-8000 pg/ml

Human IL-1 sRI ELISA Kit - RAB0279 from Sigma-Aldrich Category ELISA Kit Prices $666.00 Sizes 1 kt

Human IL-1 RI DuoSet ELISA - DY269 from R&D Systems Category ELISA Kit Prices $649.00 Sizes 1 kit (for 15 Plates) Range 125.00 - 8,000 pg/mL

Mouse IL-1 RI DuoSet ELISA - DY771-05 from R&D Systems Category ELISA Kit Prices $299.00 Sizes 1 kit (for 5 Plates) Range 93.80 - 6,000 pg/mL

Human IL1RA ELISA Kit - 55R-1756 from Fitzgerald Category ELISA Kit Prices $460.00 Sizes 1 kit

IL-1 R1 ELISA Kit (Human) : 96 Wells (OKAG00128) - OKAG00128 from Aviva Systems Biology Category ELISA Kit Prices $390.00 Sizes 96 wells Sensitivity 125 pg/mL Range 125-8,000 pg/mL

Human IL1R1 ELISA Kit - orb180591 from Biorbyt Category ELISA Kit Prices $570.00 Sizes 96 well Sensitivity < 10 pg/ml Range 125 pg/ml-8000 pg/ml

Human IL1R1 ELISA Kit - abx151933 from Abbexa Category ELISA Kit Sensitivity 0.049 ng/ml Range 0.156 ng/ml - 10 ng/ml

Human IL1RA ELISA Kit - abx151935 from Abbexa Category ELISA Kit Sensitivity 12.2 pg/ml Range 31.25 pg/ml - 2000 pg/ml

Interleukin 1 Receptor Type I, IL1R1, Human, ELISA Kit - E-EL-H1028 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 0.094 Range 0.156-10ng/mL

Interleukin 1 Receptor Type I (IL1R1), Human, ELISA Kit - SEA066Hu from ARP American Research Products Category ELISA Kit Prices $650.00 Sizes 96 t Sensitivity 0.049ng/mL Range 0.156-10ng/mL

Interleukin-1 receptor type 1, IL1R1, Human, ELISA Kit - E0065h from ARP American Research Products Category ELISA Kit Prices $476.00 Sizes 96 t Range 0.156-10 ng/mL

Soluble interleukin-1 receptor I, IL-1sRI, Human, ELISA Kit - CSB-E04611h from ARP American Research Products Category ELISA Kit Prices $450.00, $595.00, $596.00, $599.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 23.5 pg/ml Range 94 pg/ml-6000 pg/ml

IL1R1 (Human) ELISA Kit - KA2210 from Acris Antibodies Category ELISA Kit Prices $650.00 Sizes 1 kit

Human IL-1 sRI ELISA - ELH-IL1R1 from RayBiotech Category ELISA Kit Prices $390.00, $702.00, $1,561.00 Sizes 1 plate kit, 2 plate kit, 5 plate kit Sensitivity 6 pg/ml Range 6 pg/ml - 2000 pg/ml

Human IL1RA ELISA Kit - HI0322 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Anserine IL1RA ELISA Kit - AI0322 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Interleukin 1 Receptor Type I, ELISA Kit - MBS104709 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Interleukin 1 Receptor Type I, ELISA Kit - MBS090397 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Interleukin 1 Receptor Type I, ELISA Kit - MBS058658 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Interleukin 1 Receptor Type I, ELISA Kit - MBS074787 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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