IL1R1

Gene Symbol IL1R1
Entrez Gene 3554
Alt Symbol CD121A, D2S1473, IL-1R-alpha, IL1R, IL1RA, P80
Species Human
Gene Type protein-coding
Description interleukin 1 receptor, type I
Other Description CD121 antigen-like family member A|IL-1R-1|IL-1RT-1|IL-1RT1|interleukin 1 receptor alpha, type I|interleukin-1 receptor alpha|interleukin-1 receptor type 1|interleukin-1 receptor type I
Swissprots Q587I7 P14778
Accessions AAM88423 AAX81988 CAD57171 CCF76934 EAX01799 P14778 AK026803 AK314433 AL548240 BC067506 AAH67506 BC067507 AAH67507 BC067508 AAH67508 BC075062 AAH75062 BC075063 AAH75063 BE144272 BQ021163 DA861783 HY092388 M27492 AAA59137 X16896 CAA34773 XM_005263929 XP_005263986 XM_005263930 XP_005263987 XM_005263931 XP_005263988 XM_005263932 XP_005263989 XM_005263933 XP_005263990 XM_005263934 XP_005263991 XM_011511114 XP_011509416 XM_011511115 XP_011509417 XM_011511116 XP_011509418 XM_011511117 XP_011509419 XM_011511118 XP_011509420 XM_011511119 XP_011509421 XM_011511120 XP_011509422 NM_000877 NP_000868 NM_001288706 NP_001275635
Function Receptor for IL1A, IL1B and IL1RN. After binding to interleukin-1 associates with the corecptor IL1RAP to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B, MAPK and other pathways. Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits. Binds ligands with comparable affinity and binding of antagonist IL1RN prevents association with IL1RAP to form a signaling complex. {ECO:0000269|PubMed:10671496}.
Subcellular Location Membrane {ECO:0000269|PubMed:8142597}; Single-pass type I membrane protein {ECO:0000269|PubMed:8142597}. Cell membrane {ECO:0000305|PubMed:8142597}. Secreted {ECO:0000269|PubMed:8142597}.
Top Pathways Amoebiasis, Inflammatory mediator regulation of TRP channels, HTLV-I infection, Osteoclast differentiation, Cytokine-cytokine receptor interaction

IL1R1 - MBS1268393 from MyBioSource

Prices $175.00
Sizes 10ug plasmid + 200ul glycerol stock
Species Human
Accession BC067506

Human IL1R1 cDNA clone(NM_000877.2) - CDFH009165 from Creative Biomart

Species Human
Accession NM_000877.2

Human IL1R1 ORF Clone(NM_000877.2) - CDCR337906 from Creative Biomart

Species Human
Accession NM_000877.2

Human IL1R1 ORF Clone(NM_000877.2) - CDCR337907 from Creative Biomart

Species Human
Accession NM_000877.2

Human IL1R1 ORF Clone(NM_000877.2) - CDCL167103 from Creative Biomart

Species Human
Accession NM_000877.2

Human IL1R1 ORF clone(NM_000877.2) - CDCL184820 from Creative Biomart

Species Human
Accession NM_000877.2

Mouse IL-1 RI (NP_032388) VersaClone cDNA - RDC1515 from R&D Systems

Prices $199.00
Sizes 10 µg
Species Mouse

Human IL1R1 ORF clone(NM_000877.2) - CDCL184820 from Creative biogene

Species Human

Human IL1R1 ORF Clone (BC067506) - CDCS405969 from Creative biogene

Species Human
Accession P14778

Human IL1R1 cDNA Clone(NM_000877.2) - CDFH009165 from Creative biogene

Species Human
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