Gene Symbol | LAMP3 |
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Entrez Gene | 27074 |
Alt Symbol | CD208, DC LAMP, DC-LAMP, DCLAMP, LAMP, LAMP-3, TSC403 |
Species | Human |
Gene Type | protein-coding |
Description | lysosomal-associated membrane protein 3 |
Other Description | DC-lysosome-associated membrane glycoprotein|lysosome-associated membrane glycoprotein 3 |
Swissprots | O94781 Q9UQV4 Q8NEC8 D3DNS4 |
Accessions | CBX47465 EAW78337 EAW78338 Q9UQV4 AB013924 BAA34533 AJ005766 CAA06691 AK302894 BAG64067 AK313172 BAG35989 BC032940 AAH32940 BI462212 DA994656 DC399447 DQ892118 ABM83044 XM_005247360 XP_005247417 XM_006713586 XP_006713649 XM_011512688 XP_011510990 XR_924123 XR_924124 NM_014398 NP_055213 |
Function | May play a role in dendritic cell function and in adaptive immunity. {ECO:0000269|PubMed:9768752}. |
Subcellular Location | Lysosome membrane; Single-pass type I membrane protein. Cytoplasmic vesicle membrane; Single-pass type I membrane protein. Note=During dendritic cell maturation, detected on cytoplasmic vesicles (the MHC II compartment) that contain MHC II proteins, LAMP1, LAMP2 and LAMP3. Detected on lysosomes in mature dendritic cells. |
Tissue Specificity | Detected in tonsil interdigitating dendritic cells, in spleen, lymph node, Peyer's patches in the small instestine, in thymus medulla and in B-cells (at protein level). Expressed in lymphoid organs and dendritic cells. Expressed in lung. Up-regulated in carcinomas of the esophagus, colon, rectum, ureter, stomach, breast, fallopian tube, thyroid and parotid tissues. {ECO:0000269|PubMed:21930964, ECO:0000269|PubMed:9721848, ECO:0000269|PubMed:9768752}. |
Top Pathways | Lysosome |
Cluster of differentiation 63, CD63, Human, ELISA Kit - CSB-E14107h from ARP American Research Products
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Tetraspanin 30 (TSPAN30), Human, ELISA Kit - SEB345Hu from ARP American Research Products
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Tetraspanin 30 (TSPAN30), Human, CLIA Kit - SCB345Hu from ARP American Research Products
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lysosomal-associated membrane protein 3, ELISA Kit - MBS9325053 from MyBioSource
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Human CD208 / DC-LAMP / LAMP3 ELISA Pair Set - SEK10527-5 from Sino Biological
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Human CD208/ DC-LAMP / LAMP3 ELISA Kit - NS-E10028 from Novatein Biosciences
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Human LAMP3 ELISA Kit - E023266 from Biobool
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Lysosome-associated membrane glycoprotein 3, ELISA Kit - MBS284004 from MyBioSource
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Lysosome-Associated Membrane Glycoprotein 3 (LAMP3), ELISA Kit - MBS9903219 from MyBioSource
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Lysosome-Associated Membrane Glycoprotein 3 (LAMP3), ELISA Kit - MBS9903227 from MyBioSource
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Lysosome-Associated Membrane Glycoprotein 3 (LAMP3), ELISA Kit - MBS9903212 from MyBioSource
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