LAMP3

Gene Symbol LAMP3
Entrez Gene 27074
Alt Symbol CD208, DC LAMP, DC-LAMP, DCLAMP, LAMP, LAMP-3, TSC403
Species Human
Gene Type protein-coding
Description lysosomal-associated membrane protein 3
Other Description DC-lysosome-associated membrane glycoprotein|lysosome-associated membrane glycoprotein 3
Swissprots O94781 Q9UQV4 Q8NEC8 D3DNS4
Accessions CBX47465 EAW78337 EAW78338 Q9UQV4 AB013924 BAA34533 AJ005766 CAA06691 AK302894 BAG64067 AK313172 BAG35989 BC032940 AAH32940 BI462212 DA994656 DC399447 DQ892118 ABM83044 XM_005247360 XP_005247417 XM_006713586 XP_006713649 XM_011512688 XP_011510990 XR_924123 XR_924124 NM_014398 NP_055213
Function May play a role in dendritic cell function and in adaptive immunity. {ECO:0000269|PubMed:9768752}.
Subcellular Location Lysosome membrane; Single-pass type I membrane protein. Cytoplasmic vesicle membrane; Single-pass type I membrane protein. Note=During dendritic cell maturation, detected on cytoplasmic vesicles (the MHC II compartment) that contain MHC II proteins, LAMP1, LAMP2 and LAMP3. Detected on lysosomes in mature dendritic cells.
Tissue Specificity Detected in tonsil interdigitating dendritic cells, in spleen, lymph node, Peyer's patches in the small instestine, in thymus medulla and in B-cells (at protein level). Expressed in lymphoid organs and dendritic cells. Expressed in lung. Up-regulated in carcinomas of the esophagus, colon, rectum, ureter, stomach, breast, fallopian tube, thyroid and parotid tissues. {ECO:0000269|PubMed:21930964, ECO:0000269|PubMed:9721848, ECO:0000269|PubMed:9768752}.
Top Pathways Lysosome

DC-LAMP CRISPR/Cas9 KO Plasmid (h) - sc-406609 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DC-LAMP HDR Plasmid (h) - sc-406609-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DC-LAMP Double Nickase Plasmid (h) - sc-406609-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DC-LAMP Double Nickase Plasmid (h2) - sc-406609-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DC-LAMP CRISPR Activation Plasmid (h) - sc-406609-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DC-LAMP CRISPR Activation Plasmid (h2) - sc-406609-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DC-LAMP Lentiviral Activation Particles (h) - sc-406609-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DC-LAMP Lentiviral Activation Particles (h2) - sc-406609-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DC-LAMP siRNA (h) - sc-77099 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

DC-LAMP shRNA Plasmid (h) - sc-77099-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

DC-LAMP shRNA (h) Lentiviral Particles - sc-77099-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU025241 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN11541 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11541 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR10628 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr10628

LAMP3 siRNA (Human) - CRH8948 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human LAMP3 (NM_014398.3) - SHH328359 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human LAMP3(NM_014398.3) - SHH141905 from Creative biogene

Category siRNA
Species Reactivities Human

LAMP3 shRNA Plasmid (Human) - CHH8948 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

LAMP3 miRNA 3'UTR clone - MiUTR1H-05568 from Creative biogene

Species Reactivities Human
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