LAMP3

Gene Symbol LAMP3
Entrez Gene 27074
Alt Symbol CD208, DC LAMP, DC-LAMP, DCLAMP, LAMP, LAMP-3, TSC403
Species Human
Gene Type protein-coding
Description lysosomal-associated membrane protein 3
Other Description DC-lysosome-associated membrane glycoprotein|lysosome-associated membrane glycoprotein 3
Swissprots O94781 Q9UQV4 Q8NEC8 D3DNS4
Accessions CBX47465 EAW78337 EAW78338 Q9UQV4 AB013924 BAA34533 AJ005766 CAA06691 AK302894 BAG64067 AK313172 BAG35989 BC032940 AAH32940 BI462212 DA994656 DC399447 DQ892118 ABM83044 XM_005247360 XP_005247417 XM_006713586 XP_006713649 XM_011512688 XP_011510990 XR_924123 XR_924124 NM_014398 NP_055213
Function May play a role in dendritic cell function and in adaptive immunity. {ECO:0000269|PubMed:9768752}.
Subcellular Location Lysosome membrane; Single-pass type I membrane protein. Cytoplasmic vesicle membrane; Single-pass type I membrane protein. Note=During dendritic cell maturation, detected on cytoplasmic vesicles (the MHC II compartment) that contain MHC II proteins, LAMP1, LAMP2 and LAMP3. Detected on lysosomes in mature dendritic cells.
Tissue Specificity Detected in tonsil interdigitating dendritic cells, in spleen, lymph node, Peyer's patches in the small instestine, in thymus medulla and in B-cells (at protein level). Expressed in lymphoid organs and dendritic cells. Expressed in lung. Up-regulated in carcinomas of the esophagus, colon, rectum, ureter, stomach, breast, fallopian tube, thyroid and parotid tissues. {ECO:0000269|PubMed:21930964, ECO:0000269|PubMed:9721848, ECO:0000269|PubMed:9768752}.
Top Pathways Lysosome

Human CD208 gene - orb91106 from Biorbyt

Prices $255.00
Sizes 10 μg
Species Human

Human LAMP3 ORF Clone(NM_014398.3) - CDCL168437 from Creative Biomart

Species Human
Accession NM_014398.3

Human CD208 ORF clone(NM_014398.3) - CDCL183235 from Creative biogene

Species Human
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