Gene Symbol | LAMP3 |
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Entrez Gene | 27074 |
Alt Symbol | CD208, DC LAMP, DC-LAMP, DCLAMP, LAMP, LAMP-3, TSC403 |
Species | Human |
Gene Type | protein-coding |
Description | lysosomal-associated membrane protein 3 |
Other Description | DC-lysosome-associated membrane glycoprotein|lysosome-associated membrane glycoprotein 3 |
Swissprots | O94781 Q9UQV4 Q8NEC8 D3DNS4 |
Accessions | CBX47465 EAW78337 EAW78338 Q9UQV4 AB013924 BAA34533 AJ005766 CAA06691 AK302894 BAG64067 AK313172 BAG35989 BC032940 AAH32940 BI462212 DA994656 DC399447 DQ892118 ABM83044 XM_005247360 XP_005247417 XM_006713586 XP_006713649 XM_011512688 XP_011510990 XR_924123 XR_924124 NM_014398 NP_055213 |
Function | May play a role in dendritic cell function and in adaptive immunity. {ECO:0000269|PubMed:9768752}. |
Subcellular Location | Lysosome membrane; Single-pass type I membrane protein. Cytoplasmic vesicle membrane; Single-pass type I membrane protein. Note=During dendritic cell maturation, detected on cytoplasmic vesicles (the MHC II compartment) that contain MHC II proteins, LAMP1, LAMP2 and LAMP3. Detected on lysosomes in mature dendritic cells. |
Tissue Specificity | Detected in tonsil interdigitating dendritic cells, in spleen, lymph node, Peyer's patches in the small instestine, in thymus medulla and in B-cells (at protein level). Expressed in lymphoid organs and dendritic cells. Expressed in lung. Up-regulated in carcinomas of the esophagus, colon, rectum, ureter, stomach, breast, fallopian tube, thyroid and parotid tissues. {ECO:0000269|PubMed:21930964, ECO:0000269|PubMed:9721848, ECO:0000269|PubMed:9768752}. |
Top Pathways | Lysosome |
LAMP3 / CD208 Antibody Blocking Peptide - LS-E5747 from LifeSpan Bioscience
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LAMP3 / CD208 Antibody Blocking Peptide - LS-E15315 from LifeSpan Bioscience
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DC-LAMP Recombinant Protein - P3677 from Novus Biologicals
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LAMP3-Antibody-N-term-Blocking-Peptide - BP1827a from Abgent, a WuXi AppTec company
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Human CD208 His tag protein - orb83220 from Biorbyt
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LAMP3 Blocking Peptide - 33R-10246 from Fitzgerald
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CD208 / LAMP3 - H00027074-H01 from Acris Antibodies
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CD208 / LAMP3 - P3677 from Acris Antibodies
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LAMP3 fusion protein - Ag8294 from Proteintech Group
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LAMP3 fusion protein - Ag3325 from Proteintech Group
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Recombinant Human LAMP3, His tagged - LAMP3-632H from Creative Biomart
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CD208 - PN201486 from Elabscience
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Human CD208 Recombinant (LAMP3) - RKQ9UQV4 from Reprokine
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Human CD208 / LAMP3 / DC-LAMP Protein (His Tag) - 10527-H08H-20 from Sino Biological
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Human CD63 / Tspan-30 / Tetraspanin-30 Protein (His Tag) - 11271-H08H-50 from Sino Biological
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Recombinant Human Lysosome-associated membrane glycoprotein 3(LAMP3) - CSB-YP892177HU CSB-EP892177HU CSB-BP892177HU CSB-MP892177HU from Cusabio
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Recombinant Lysosomal Associated Membrane Protein 3 (LAMP3) - RPB610Hu01 from Cloud-clone
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Recombinant Lysosomal Associated Membrane Protein 3 (LAMP3) - RPB610Hu01 from Uscn Life Science Inc.
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LAMP3, 28-381aa, Human, His tag, Baculovirus - ATGP3299 from ATGen
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CD208 (LAMP3) , Recombinant Protein - MBS553150 from MyBioSource
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Recombinant Human CD63 / Tspan-30 / Tetraspanin-30 Protein (His tag) - PKSH031174 from Elabscience
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Recombinant Human CD208 / LAMP3 / DC-LAMP Protein (His tag) - PKSH031547 from Elabscience
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Recombinant Human LAMP3 Protein, His-tagged - LAMP3-35H from Creative Biomart
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DC-LAMP Recombinant Protein Antigen - NBP2-33616PEP from Novus Biologicals
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CD208 / LAMP3 (28-381, His-tag) - AR52026PU-N from Acris Antibodies
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