FEM1B

Gene Symbol FEM1B
Entrez Gene 10116
Alt Symbol F1A-ALPHA, F1AA, FEM1-beta
Species Human
Gene Type protein-coding
Description fem-1 homolog b (C. elegans)
Other Description FEM-1-like death receptor binding protein|fem-1-like death receptor-binding protein alpha|fem-1-like in apoptotic pathway protein alpha|protein fem-1 homolog B
Swissprots Q9UK73 O43146
Accessions EAW77818 EAW77819 Q9UK73 AB007856 BAA23692 AF178632 AAF05314 AF204883 AAF69303 AK098620 AK290167 BAF82856 AL833264 BC010122 AAH10122 BC014558 AAH14558 BF112021 CR626996 EU176451 ABW03902 XM_006720370 XP_006720433 NM_015322 NP_056137
Function Component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit. Involved in apoptosis by acting as a death receptor-associated protein that mediates apoptosis. Also involved in glucose homeostasis in pancreatic islet. Functions as an adapter/mediator in replication stress-induced signaling that leads to the activation of CHEK1. {ECO:0000269|PubMed:10542291, ECO:0000269|PubMed:19330022}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:19330022}. Nucleus {ECO:0000269|PubMed:19330022}. Note=In the nucleus, the protein level increased slightly after camptothecin (CPT) treatment. Associated with chromatin.
Tissue Specificity Widely expressed. Highly expressed in testis. Weakly expressed in other tissues. {ECO:0000269|PubMed:10542291}.

FEM1B (C-20) - sc-67565 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

FEM1B (V-19) - sc-67568 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
FEM1B (V-19): sc-67568. Western blot analysis of FEM1B expression in FEM1B treated 293T (A), PC-3 (B) and MCF7 (C) whole cell lysates.

Anti-FEM 1B antibody - ab3686 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-FEM1B Antibody (aa284-333) - LS-C81784 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
721_B cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-FEM1B Antibody (C-Terminus) - LS-C81785 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Fetal lung lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-FEM1B Antibody (aa609-622) IHC-plus™ - LS-B568 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-FEM1B antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B568 concentration 10 ug/ml.

Anti-FEM1B Antibody (aa401-490) - LS-C307966 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-FEM1B Antibody - LS-C128907 from LifeSpan Bioscience

Prices $560.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

FEM1B Antibody - NBP1-77300 from Novus Biologicals

Prices $329.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: FEM1B Antibody [NBP1-77300] - Analysis of FEM1B in mouse (A) and rat (B) liver tissue lysates with anti- FEM1B using this antibody at 1 ug /ml.

FEM1B Antibody - NBP1-89422 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: FEM1B Antibody [NBP1-89422] - Staining of human cell line A-431 shows localization to nucleoplasm & cytosol.

FEM1B Antibody - NB100-94242 from Novus Biologicals

Prices $419.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: F1Aa Antibody [NB100-94242] - Western blot analysis of F1Aá in mouse (A) and rat (B) liver tissue lysates with anti- F1Aá at 1 ug /ml.

FEM1B Antibody - H00010116-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: FEM1B Antibody [H00010116-B01] - analysis of FEM1B expression in transfected 293T cell line by FEM1B MaxPab polyclonal antibody (B01). Lane 1: FEM1B transfected lysate (70.30 KDa). Lane 2: Non-transfected lysate.

FEM1B Antibody (4B12) - H00010116-M09 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4B12
Immunocytochemistry/Immunofluorescence: FEM1B Antibody (4B12) [H00010116-M09] - Analysis of monoclonal antibody to FEM1B on HeLa cell. Antibody concentration 10 ug/ml

FEM 1B Polyclonal Antibody - bs-7113R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin embedded rat testis labeled with Rabbit Anti-FEM 1B Polyclonal Antibody, Unconjugated (bs-7113R) at 1:200 followed by conjugation to the secondary antibody and DAB staining\\n

Anti-FEM1B antibody produced in rabbit - HPA042192 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-FEM1B: <B>Cat. No. HPA042192</B>: Immunohistochemical staining of human testis shows strong cytoplasmic positivity in cells in seminiferus ducts.

Anti-F1Aα antibody produced in rabbit - PRS2279 from Sigma-Aldrich

Prices $347.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-F1A α: <B>Cat. No. PRS2279</B> Immunohistochemistry of F1Aα in mouse liver tissue with F1Aα antibody at 5 μg/mL.

Monoclonal Anti-FEM1B antibody produced in mouse - SAB1403048 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4B12
<B>Immunofluorescence</B><BR/>Monoclonal Anti-FEM1B: <B>Cat. No. SAB1403048</B>: Antibody concentration: 10 μg/mL using HeLa cell.

Anti-FEM1B antibody produced in rabbit - SAB2900381 from Sigma-Aldrich

Prices $464.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-FEM1B: <B>Cat. No.SAB2900381</B>: Brain, cortex: Formalin-Fixed Paraffin-Embedded (FFPE).

Anti-FEM1B (AB1) antibody produced in rabbit - AV53702 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Cell Type: 721_B (<B>Cat. No. AV53702</B>).<BR/><B>Lanes</B><BR/>1. Antibody dilution (concentration) 1 μg/mL in cell type 721_B

Anti-FEM1B (AB2) antibody produced in rabbit - AV53703 from Sigma-Aldrich

Prices $347.50
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Cell Type: fetal lung (<B>Cat. No. AV53703</B>).<BR/><B>Lanes</B><BR/>1. Antibody dilution (concentration) 1 μg/mL in cell type fetal lung

Anti-FEM1B antibody produced in rabbit - HPA041920 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-FEM1B: <B>Cat. No. HPA041920</B>: Immunohistochemical staining of human colon shows moderate nuclear and cytoplasmic positivity in glandular cells.

FEM1B antibody - middle region (ARP53702_P050) - ARP53702_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

FEM1B antibody - C-terminal region (ARP53703_P050) - ARP53703_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

F1A alpha antibody - GTX23686 from GeneTex

Prices $319.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal
Anti-F1A alpha antibody used in Western blot. GTX23686

F1A alpha antibody - orb74414 from Biorbyt

Prices $723.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal
Western blot analysis of mouse (A) and rat (B) liver tissue lysates using F1A alpha antibody
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