FEM1B

Gene Symbol	FEM1B
Entrez Gene	10116
Alt Symbol	F1A-ALPHA, F1AA, FEM1-beta
Species	Human
Gene Type	protein-coding
Description	fem-1 homolog b (C. elegans)
Other Description	FEM-1-like death receptor binding protein|fem-1-like death receptor-binding protein alpha|fem-1-like in apoptotic pathway protein alpha|protein fem-1 homolog B
Swissprots	Q9UK73 O43146
Accessions	EAW77818 EAW77819 Q9UK73 AB007856 BAA23692 AF178632 AAF05314 AF204883 AAF69303 AK098620 AK290167 BAF82856 AL833264 BC010122 AAH10122 BC014558 AAH14558 BF112021 CR626996 EU176451 ABW03902 XM_006720370 XP_006720433 NM_015322 NP_056137
Function	Component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit. Involved in apoptosis by acting as a death receptor-associated protein that mediates apoptosis. Also involved in glucose homeostasis in pancreatic islet. Functions as an adapter/mediator in replication stress-induced signaling that leads to the activation of CHEK1. {ECO:0000269|PubMed:10542291, ECO:0000269|PubMed:19330022}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:19330022}. Nucleus {ECO:0000269|PubMed:19330022}. Note=In the nucleus, the protein level increased slightly after camptothecin (CPT) treatment. Associated with chromatin.
Tissue Specificity	Widely expressed. Highly expressed in testis. Weakly expressed in other tissues. {ECO:0000269|PubMed:10542291}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human FEM1B cDNA clone(NM_015322.3) - CDFH006774 from Creative Biomart Species Human Accession NM_015322.3

Human FEM1B cDNA clone(NM_015322.3) - CDFH006775 from Creative Biomart Species Human Accession NM_015322.3

Human FEM1B ORF Clone(NM_015322.3) - CDCL163400 from Creative Biomart Species Human Accession NM_015322.3

Human FEM1B ORF clone(NM_015322.3) - CDCL184223 from Creative Biomart Species Human Accession NM_015322.3

Human FEM1B ORF clone - CDCL107801 from Creative Biomart Species Human Accession NM_015322

Human FEM1B ORF clone - CDCL107802 from Creative Biomart Species Human Accession NM_015322

Human FEM1B ORF Clone(NM_015322.3) - CDCR299292 from Creative Biomart Species Human Accession NM_015322.3

Human FEM1B ORF Clone(NM_015322.3) - CDCR299293 from Creative Biomart Species Human Accession NM_015322.3

Human FEM1B ORF Clone(NM_015322.3) - CDCR299294 from Creative Biomart Species Human Accession NM_015322.3

Human FEM1B Gene cDNA clone plasmid - HG11180-M from Sino Biological Species Human

Human FEM1B Gene ORF cDNA clone expression plasmid, N-HA tag - HG11180-NY from Sino Biological Species Human

Human FEM1B Gene ORF cDNA clone expression plasmid, C-Flag tag - HG11180-CF from Sino Biological Species Human

Human FEM1B Gene ORF cDNA clone expression plasmid, N-His tag - HG11180-NH from Sino Biological Species Human

Human FEM1B Gene ORF cDNA clone expression plasmid, C-Myc tag - HG11180-CM from Sino Biological Species Human

Human FEM1B Gene ORF cDNA clone expression plasmid, C-His tag - HG11180-CH from Sino Biological Species Human

Human FEM1B Gene ORF cDNA clone expression plasmid, C-HA tag - HG11180-CY from Sino Biological Species Human

Human FEM1B Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG11180-ACR from Sino Biological Species Human

Human FEM1B Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG11180-ANR from Sino Biological Species Human

Human FEM1B Gene ORF cDNA clone expression plasmid - HG11180-UT from Sino Biological Species Human

Human FEM1B Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG11180-ACG from Sino Biological Species Human

Human FEM1B Gene cDNA Clone (full-length ORF Clone), expression ready, untagged - HG11180-M-N from Sino Biological Species Human Accession NM_015322.3

Human FEM1B Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG11180-ANG from Sino Biological Species Human

Human FEM1B Gene ORF cDNA clone expression plasmid, N-Flag tag - HG11180-NF from Sino Biological Species Human

Human FEM1B Gene ORF cDNA clone expression plasmid, N-Myc tag - HG11180-NM from Sino Biological Species Human

Human FEM1B ORF clone(NM_015322.3) - CDCL184223 from Creative biogene Species Human

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