Gene Symbol | FEM1B |
---|---|
Entrez Gene | 10116 |
Alt Symbol | F1A-ALPHA, F1AA, FEM1-beta |
Species | Human |
Gene Type | protein-coding |
Description | fem-1 homolog b (C. elegans) |
Other Description | FEM-1-like death receptor binding protein|fem-1-like death receptor-binding protein alpha|fem-1-like in apoptotic pathway protein alpha|protein fem-1 homolog B |
Swissprots | Q9UK73 O43146 |
Accessions | EAW77818 EAW77819 Q9UK73 AB007856 BAA23692 AF178632 AAF05314 AF204883 AAF69303 AK098620 AK290167 BAF82856 AL833264 BC010122 AAH10122 BC014558 AAH14558 BF112021 CR626996 EU176451 ABW03902 XM_006720370 XP_006720433 NM_015322 NP_056137 |
Function | Component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit. Involved in apoptosis by acting as a death receptor-associated protein that mediates apoptosis. Also involved in glucose homeostasis in pancreatic islet. Functions as an adapter/mediator in replication stress-induced signaling that leads to the activation of CHEK1. {ECO:0000269|PubMed:10542291, ECO:0000269|PubMed:19330022}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:19330022}. Nucleus {ECO:0000269|PubMed:19330022}. Note=In the nucleus, the protein level increased slightly after camptothecin (CPT) treatment. Associated with chromatin. |
Tissue Specificity | Widely expressed. Highly expressed in testis. Weakly expressed in other tissues. {ECO:0000269|PubMed:10542291}. |
FEM 1B peptide - ab6098 from Abcam
|
||||||||||
Human FEM 1B full length protein - ab160829 from Abcam
|
||||||||||
Human FEM 1B peptide - ab22783 from Abcam
|
||||||||||
Human FEM 1B protein fragment - ab160830 from Abcam
|
||||||||||
FEM1B Antibody Blocking Peptide - LS-E19418 from LifeSpan Bioscience
|
||||||||||
FEM1B Antibody Blocking Peptide - LS-E19419 from LifeSpan Bioscience
|
||||||||||
FEM1B Antibody Blocking Peptide - LS-E29935 from LifeSpan Bioscience
|
||||||||||
Recombinant Human FEM1B Protein - H00010116-P01 from Novus Biologicals
|
||||||||||
Recombinant Human FEM1B Protein - H00010116-Q01 from Novus Biologicals
|
||||||||||
FEM1B Blocking Peptide - NBP1-77300PEP from Novus Biologicals
|
||||||||||
F1A alpha peptide - GTX26098 from GeneTex
|
||||||||||
FEM1B Blocking Peptide - 33R-3027 from Fitzgerald
|
||||||||||
FEM1B Blocking Peptide - 33R-2032 from Fitzgerald
|
||||||||||
FEM1B - H00010116-P01-10 from Acris Antibodies
|
||||||||||
FEM1B - H00010116-P01-25 from Acris Antibodies
|
||||||||||
FEM1B - H00010116-Q01-10 from Acris Antibodies
|
||||||||||
FEM1B - H00010116-Q01-25 from Acris Antibodies
|
||||||||||
FEM1B Control Peptide - AP30325CP-N from Acris Antibodies
|
||||||||||
F1A alpha Peptide - 2279P from ProSci
|
||||||||||
FEM1B fusion protein - ag1497 from Proteintech Group
|
||||||||||
Recombinant Human Protein fem-1 homolog B(FEM1B) - CSB-YP891718HU CSB-EP891718HU CSB-BP891718HU CSB-MP891718HU from Cusabio
|
||||||||||
FEM1B - TP303618 from Acris Antibodies
|
||||||||||
Synthetic Human FEM1B (aa 609-622) Blocking Peptide - PX125BP from Cell Science
|
||||||||||
FEM1B Protein - NBP1-89422PEP from Novus Biologicals
|
||||||||||
FEM1B Recombinant Protein Antigen - NBP1-86219PEP from Novus Biologicals
|