FEM1B

Gene Symbol FEM1B
Entrez Gene 10116
Alt Symbol F1A-ALPHA, F1AA, FEM1-beta
Species Human
Gene Type protein-coding
Description fem-1 homolog b (C. elegans)
Other Description FEM-1-like death receptor binding protein|fem-1-like death receptor-binding protein alpha|fem-1-like in apoptotic pathway protein alpha|protein fem-1 homolog B
Swissprots Q9UK73 O43146
Accessions EAW77818 EAW77819 Q9UK73 AB007856 BAA23692 AF178632 AAF05314 AF204883 AAF69303 AK098620 AK290167 BAF82856 AL833264 BC010122 AAH10122 BC014558 AAH14558 BF112021 CR626996 EU176451 ABW03902 XM_006720370 XP_006720433 NM_015322 NP_056137
Function Component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit. Involved in apoptosis by acting as a death receptor-associated protein that mediates apoptosis. Also involved in glucose homeostasis in pancreatic islet. Functions as an adapter/mediator in replication stress-induced signaling that leads to the activation of CHEK1. {ECO:0000269|PubMed:10542291, ECO:0000269|PubMed:19330022}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:19330022}. Nucleus {ECO:0000269|PubMed:19330022}. Note=In the nucleus, the protein level increased slightly after camptothecin (CPT) treatment. Associated with chromatin.
Tissue Specificity Widely expressed. Highly expressed in testis. Weakly expressed in other tissues. {ECO:0000269|PubMed:10542291}.

FEM1B CRISPR/Cas9 KO Plasmid (h) - sc-409769 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FEM1B HDR Plasmid (h) - sc-409769-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FEM1B Double Nickase Plasmid (h) - sc-409769-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FEM1B Double Nickase Plasmid (h2) - sc-409769-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FEM1B CRISPR Activation Plasmid (h) - sc-409769-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FEM1B CRISPR Activation Plasmid (h2) - sc-409769-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FEM1B Lentiviral Activation Particles (h) - sc-409769-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FEM1B Lentiviral Activation Particles (h2) - sc-409769-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FEM1B siRNA (h) - sc-62311 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

FEM1B shRNA Plasmid (h) - sc-62311-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

FEM1B shRNA (h) Lentiviral Particles - sc-62311-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

FEM1B RNAi - H00010116-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU049751 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN8618 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8618 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

FEM1B siRNA (Human) - CRH6821 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

FEM1B - MBS8241170 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human FEM1B (NM_015322.3) - SHH294013 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human FEM1B(NM_015322.3) - SHH055577 from Creative biogene

Category siRNA
Species Reactivities Human

Human FEM1B siRNA - orb267323 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

FEM1B shRNA Plasmid (Human) - CHH6821 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

FEM1B miRNA 3'UTR clone - MiUTR1H-03609 from Creative biogene

Species Reactivities Human
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