FEM1B

Gene Symbol	FEM1B
Entrez Gene	10116
Alt Symbol	F1A-ALPHA, F1AA, FEM1-beta
Species	Human
Gene Type	protein-coding
Description	fem-1 homolog b (C. elegans)
Other Description	FEM-1-like death receptor binding protein|fem-1-like death receptor-binding protein alpha|fem-1-like in apoptotic pathway protein alpha|protein fem-1 homolog B
Swissprots	Q9UK73 O43146
Accessions	EAW77818 EAW77819 Q9UK73 AB007856 BAA23692 AF178632 AAF05314 AF204883 AAF69303 AK098620 AK290167 BAF82856 AL833264 BC010122 AAH10122 BC014558 AAH14558 BF112021 CR626996 EU176451 ABW03902 XM_006720370 XP_006720433 NM_015322 NP_056137
Function	Component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit. Involved in apoptosis by acting as a death receptor-associated protein that mediates apoptosis. Also involved in glucose homeostasis in pancreatic islet. Functions as an adapter/mediator in replication stress-induced signaling that leads to the activation of CHEK1. {ECO:0000269|PubMed:10542291, ECO:0000269|PubMed:19330022}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:19330022}. Nucleus {ECO:0000269|PubMed:19330022}. Note=In the nucleus, the protein level increased slightly after camptothecin (CPT) treatment. Associated with chromatin.
Tissue Specificity	Widely expressed. Highly expressed in testis. Weakly expressed in other tissues. {ECO:0000269|PubMed:10542291}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

FEM1B 293T Cell Transient Overexpression Lysate(Denatured) - H00010116-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

FEM1B overexpression lysate - LY414619 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

FEM1B 293 Cell Lysate - 407003 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg Species C. elegans

FEM1B Overexpression Lysate (Denatured) - H00010116-T01 from Novus Biologicals Category Cell Lysate Prices $299.00 Sizes 100 µl Species Human

FEM1B Overexpression Lysate (Native) - NBL1-10674 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

FEM1B (h): 293T Lysate - sc-171706 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

FEM1B Over-expression Lysate Product - GWB-2E8451 from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

Panoply™ Human FEM1B Knockdown Stable Cell Line - CSC-DC005667 from Creative biogene Category Cell Line Species Human

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