ENPP7

Gene Symbol	ENPP7
Entrez Gene	339221
Alt Symbol	ALK-SMase, E-NPP 7, NPP-7, NPP7
Species	Human
Gene Type	protein-coding
Description	ectonucleotide pyrophosphatase/phosphodiesterase 7
Other Description	alkaline sphingomyelin phosphodiesterase|alkaline sphingomyelinase|ectonucleotide pyrophosphatase/phosphodiesterase family member 7|intestinal alkaline sphingomyelinase
Swissprots	Q8IUS8 Q6ZTS5 Q6UWV6
Accessions	EAW89566 Q6UWV6 AK126250 BAC86504 AK128662 AY230663 AAP69661 AY358622 AAQ88985 BC041453 AAH41453 DB187443 XM_011524737 XP_011523039 NM_178543 NP_848638
Function	Converts sphingomyelin to ceramide. Also has phospholipase C activity toward palmitoyl lyso-phosphocholine. Does not appear to have nucleotide pyrophosphatase activity. {ECO:0000269|PubMed:12885774}.
Subcellular Location	Membrane {ECO:0000269|PubMed:12671034, ECO:0000305}; Single-pass type I membrane protein {ECO:0000269|PubMed:12671034, ECO:0000305}. Note=Localized at the surface of the microvillar membrane in small intestine enterocytes, and in endosome-like structures situated beneath the microvillar membrane, and in Golgi complex. {ECO:0000269|PubMed:12671034, ECO:0000269|PubMed:12885774}.
Tissue Specificity	Detected in the colon (at protein level). Expressed in the duodenum, jejunum and liver and at low levels in the ileum. Expression was very low in the esophagus, stomach and colon. {ECO:0000269|PubMed:12671034, ECO:0000269|PubMed:12885774}.
Top Pathways	Sphingolipid metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Alk-SMase (H-155) - sc-134737 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

Alk-SMase (D-17) - sc-49352 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Anti-ENPP7 antibody - ab69463 from Abcam Prices $370.00 Sizes 50 µg Host Mouse Clonality Polyclonal

Anti-ENPP7 antibody - ab104266 from Abcam Prices $370.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-ENPP7 antibody - ab121827 from Abcam Prices $443.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-ENPP7 antibody [EPR12329] - ab174281 from Abcam Prices $357.00 Sizes 100 µl Host Rabbit Clonality Monoclonal Clone EPR12329

Anti-ENPP7 antibody - N-terminal - ab177963 from Abcam Prices $370.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-ENPP7 Antibody - LS-C332284 from LifeSpan Bioscience Prices $255.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-ENPP7 Antibody - LS-C143834 from LifeSpan Bioscience Prices $465.00 Sizes 100 µg Host Mouse Clonality Monoclonal

Anti-ENPP7 Antibody (aa286-313, Biotin) - LS-C234963 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-ENPP7 Antibody (aa286-313, APC) - LS-C234964 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-ENPP7 Antibody (aa286-313, FITC) - LS-C234965 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-ENPP7 Antibody (aa286-313, PE) - LS-C234969 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-ENPP7 Antibody (aa286-313, Azide-free, HRP) - LS-C249913 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-ENPP7 Antibody (aa286-313, AP) - LS-C246890 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-ENPP7 Antibody - LS-C307924 from LifeSpan Bioscience Prices $455.00 Sizes 50 µg Host Mouse Clonality Polyclonal

Anti-ENPP7 Antibody (aa290-320) - LS-C321122 from LifeSpan Bioscience Prices $345.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-ENPP7 Antibody (aa127-176) - LS-C186981 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-EDNRB / Endothelin B Receptor Antibody - LS-C341504 from LifeSpan Bioscience Prices $385.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-ENPP7 Antibody (aa187-236) - LS-C186980 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-ENPP7 Antibody (aa286-313) - LS-C167768 from LifeSpan Bioscience Prices $295.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

ENPP-7/Alk-SMase Antibody (560514) - MAB4924 from Novus Biologicals Prices $99.00, $249.00 Sizes 25 µg, 100 µg Host Mouse Clonality Monoclonal Clone 560514

ENPP-7/Alk-SMase Antibody - AF4924 from Novus Biologicals Prices $99.00, $359.00 Sizes 25 µg, 100 µg Host Goat Clonality Polyclonal

ENPP-7/Alk-SMase Antibody - H00339221-B01P from Novus Biologicals Prices $359.00 Sizes 50 µg Host Mouse Clonality Polyclonal

ENPP-7/Alk-SMase Antibody - NBP1-89138 from Novus Biologicals Prices $419.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

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