ENPP7

Gene Symbol	ENPP7
Entrez Gene	339221
Alt Symbol	ALK-SMase, E-NPP 7, NPP-7, NPP7
Species	Human
Gene Type	protein-coding
Description	ectonucleotide pyrophosphatase/phosphodiesterase 7
Other Description	alkaline sphingomyelin phosphodiesterase|alkaline sphingomyelinase|ectonucleotide pyrophosphatase/phosphodiesterase family member 7|intestinal alkaline sphingomyelinase
Swissprots	Q8IUS8 Q6ZTS5 Q6UWV6
Accessions	EAW89566 Q6UWV6 AK126250 BAC86504 AK128662 AY230663 AAP69661 AY358622 AAQ88985 BC041453 AAH41453 DB187443 XM_011524737 XP_011523039 NM_178543 NP_848638
Function	Converts sphingomyelin to ceramide. Also has phospholipase C activity toward palmitoyl lyso-phosphocholine. Does not appear to have nucleotide pyrophosphatase activity. {ECO:0000269|PubMed:12885774}.
Subcellular Location	Membrane {ECO:0000269|PubMed:12671034, ECO:0000305}; Single-pass type I membrane protein {ECO:0000269|PubMed:12671034, ECO:0000305}. Note=Localized at the surface of the microvillar membrane in small intestine enterocytes, and in endosome-like structures situated beneath the microvillar membrane, and in Golgi complex. {ECO:0000269|PubMed:12671034, ECO:0000269|PubMed:12885774}.
Tissue Specificity	Detected in the colon (at protein level). Expressed in the duodenum, jejunum and liver and at low levels in the ileum. Expression was very low in the esophagus, stomach and colon. {ECO:0000269|PubMed:12671034, ECO:0000269|PubMed:12885774}.
Top Pathways	Sphingolipid metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human ENPP7 full length protein - ab166261 from Abcam Category Protein Source Wheat germ Species Human

ENPP7 Antibody Blocking Peptide - LS-E7648 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ENPP7 Antibody Blocking Peptide - LS-E24971 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ENPP7 Antibody Blocking Peptide - LS-E24972 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human ENPP-7/Alk-SMase Protein - H00339221-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

ENPP7-Antibody-Center-Blocking-Peptide - BP4923c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Recombinant Human ENPP-7/Alk-SMase, CF - 4924-EN-010 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived, Ala22-Ser439, with a C-terminal 10-His tag

Human ENPP7 His tag protein - orb83283 from Biorbyt Category Protein Prices $400.00, $612.00 Sizes 10 μg, 20 μg Source Human Species Human

ENPP7 - H00339221-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

ENPP7 - H00339221-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

Recombinant Human ENPP7, His-tagged - ENPP7-865H from Creative Biomart Category Protein Source NSO Cells Species Human

Recombinant Human ENPP7, His-tagged - ENPP7-287 from Creative Biomart Category Protein Source Human Cells (HEK293) .

ENPP7 - PN201549 from Elabscience Category Protein Prices $225.00, $475.00 Sizes 10 μg, 50 μg Source Human Cells Species Human

Recombinant Alkaline Sphingomyelinase (Alk-Smase) - RPA801Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Alkaline Sphingomyelinase (Alk-Smase) - RPA801Mu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Recombinant Alkaline Sphingomyelinase (Alk-Smase) - RPA801Mu02 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Recombinant Alkaline Sphingomyelinase (Alk-Smase) - RPA801Ra01 from Uscn Life Science Inc. Category Protein Source E.coli Species Rat

Human ENPP7 / NPP-7 Protein (His Tag) - 10885-H08H-10 from Sino Biological Category Protein Source Human Cells Species Human

Recombinant Alkaline Sphingomyelinase (Alk-Smase) - RPA801Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human ENPP-7/Alk-SMase Protein, CF - 4924-EN from R&D Systems Category Protein Prices $329.00 Sizes 10 µg Source Mouse myeloma cell line, NS0-derived Ala22-Ser439, with a C-terminal 10-His tag Species Human

Recombinant Human ENPP7 / NPP-7 Protein (His tag) - PKSH031375 from Elabscience Category Protein Source Human Cell Species Human

ENPP-7/Alk-SMase Recombinant Protein Antigen - NBP1-89138PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Source E.coli Species Human

ENPP7 Peptide, Human - M34GP04951H from Creative Peptides Category Peptide Source Synthetic. Species Human

Ectonucleotide pyrophosphatase/phosphodiesterase family member 7 (ENPP7), Recombinant Protein - MBS7014265 from MyBioSource Category Protein Prices $1,240.00, $2,225.00, $3,435.00 Sizes 10 µg, 50 µg, 100 µg Source Cell Free Expression Species Human

ENPP7 / NPP-7, Recombinant Protein - MBS2546031 from MyBioSource Category Protein Prices $475.00, $775.00 Sizes 10 µg, 20 µg Source Human Cells

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