ENPP7

Gene Symbol	ENPP7
Entrez Gene	339221
Alt Symbol	ALK-SMase, E-NPP 7, NPP-7, NPP7
Species	Human
Gene Type	protein-coding
Description	ectonucleotide pyrophosphatase/phosphodiesterase 7
Other Description	alkaline sphingomyelin phosphodiesterase|alkaline sphingomyelinase|ectonucleotide pyrophosphatase/phosphodiesterase family member 7|intestinal alkaline sphingomyelinase
Swissprots	Q8IUS8 Q6ZTS5 Q6UWV6
Accessions	EAW89566 Q6UWV6 AK126250 BAC86504 AK128662 AY230663 AAP69661 AY358622 AAQ88985 BC041453 AAH41453 DB187443 XM_011524737 XP_011523039 NM_178543 NP_848638
Function	Converts sphingomyelin to ceramide. Also has phospholipase C activity toward palmitoyl lyso-phosphocholine. Does not appear to have nucleotide pyrophosphatase activity. {ECO:0000269|PubMed:12885774}.
Subcellular Location	Membrane {ECO:0000269|PubMed:12671034, ECO:0000305}; Single-pass type I membrane protein {ECO:0000269|PubMed:12671034, ECO:0000305}. Note=Localized at the surface of the microvillar membrane in small intestine enterocytes, and in endosome-like structures situated beneath the microvillar membrane, and in Golgi complex. {ECO:0000269|PubMed:12671034, ECO:0000269|PubMed:12885774}.
Tissue Specificity	Detected in the colon (at protein level). Expressed in the duodenum, jejunum and liver and at low levels in the ileum. Expression was very low in the esophagus, stomach and colon. {ECO:0000269|PubMed:12671034, ECO:0000269|PubMed:12885774}.
Top Pathways	Sphingolipid metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human ENPP7 cDNA clone(NM_178543.3) - CDFG011593 from Creative Biomart Species Human Accession NM_178543.3

Human ENPP7 ORF Clone(NM_178543.3) - CDCL162393 from Creative Biomart Species Human Accession NM_178543.3

Human ENPP7 ORF Clone(NM_178543.3) - CDCR323434 from Creative Biomart Species Human Accession NM_178543.3

Human ENPP7 ORF Clone(NM_178543.3) - CDCR323435 from Creative Biomart Species Human Accession NM_178543.3

Human ENPP7 Gene ORF cDNA clone in cloning vector - HG10885-M from Sino Biological Species Human

Human ENPP7 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG10885-NF from Sino Biological Species Human

Human ENPP7 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG10885-NM from Sino Biological Species Human

Human ENPP7 Gene ORF cDNA clone expression plasmid, C-HA tag - HG10885-CY from Sino Biological Species Human

Human ENPP7 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG10885-CF from Sino Biological Species Human

Human ENPP7 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG10885-M-F from Sino Biological Species Human

Human ENPP-7 Gene cDNA Clone (full-length ORF Clone), expression ready, untagged - HG10885-M-N from Sino Biological Species Human Accession NM_178543.3

Human ENPP7 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG10885-CM from Sino Biological Species Human

Human ENPP7 Gene ORF cDNA clone expression plasmid, N-His tag - HG10885-NH from Sino Biological Species Human

Human ENPP7 Gene ORF cDNA clone expression plasmid, N-HA tag - HG10885-NY from Sino Biological Species Human

Human ENPP7 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG10885-ACR from Sino Biological Species Human

Human ENPP7 Gene ORF cDNA clone expression plasmid, C-His tag - HG10885-CH from Sino Biological Species Human

Human ENPP7 Gene ORF cDNA clone expression plasmid - HG10885-UT from Sino Biological Species Human

Human ENPP7 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG10885-ACG from Sino Biological Species Human

Human ENPP-7 ORF clone(NM_178543.3) - CDCL184049 from Creative biogene Species Human

Human ENPP7 cDNA Clone(NM_178543.3) - CDFG011593 from Creative biogene Species Human

Human ALK SMase Gene - orb91344 from Biorbyt Prices $264.00 Sizes 10 μg Species Human

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