BMX

Gene Symbol	BMX
Entrez Gene	660
Alt Symbol	ETK, PSCTK2, PSCTK3
Species	Human
Gene Type	protein-coding
Description	BMX non-receptor tyrosine kinase
Other Description	BTK-like on X chromosome|Etk/Bmx cytosolic tyrosine kinase|NTK38 tyrosine kinase|bone marrow tyrosine kinase gene in chromosome X protein|cytoplasmic tyrosine-protein kinase BMX|epithelial and endothelial tyrosine kinase
Swissprots	O60564 P51813 Q12871 A6NIH9
Accessions	EAW98889 EAW98890 P51813 AF045459 AAC08966 AK291824 BAF84513 AK313568 BAG36341 BC016652 AAH16652 BP236451 BQ226991 CB998198 DQ891059 ABM81985 DQ896814 ABM87813 U08341 AAA17744 X83107 CAA58169 XM_006724510 XP_006724573 NM_001721 NP_001712 NM_203281 NP_975010
Function	Non-receptor tyrosine kinase that plays central but diverse modulatory roles in various signaling processes involved in the regulation of actin reorganization, cell migration, cell proliferation and survival, cell adhesion, and apoptosis. Participates in signal transduction stimulated by growth factor receptors, cytokine receptors, G-protein coupled receptors, antigen receptors and integrins. Induces tyrosine phosphorylation of BCAR1 in response to integrin regulation. Activation of BMX by integrins is mediated by PTK2/FAK1, a key mediator of integrin signaling events leading to the regulation of actin cytoskeleton and cell motility. Plays a critical role in TNF-induced angiogenesis, and implicated in the signaling of TEK and FLT1 receptors, 2 important receptor families essential for angiogenesis. Required for the phosphorylation and activation of STAT3, a transcription factor involved in cell differentiation. Also involved in interleukin-6 (IL6) induced differentiation. Plays also a
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:12832404}. Note=Localizes to the edges of spreading cells when complexed with BCAR1.
Tissue Specificity	Highly expressed in cells with great migratory potential, including endothelial cells and metastatic carcinoma cell lines.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Mouse/Human ETK / BMX ELISA Kit (Cell-Based ELISA) - LS-F3117 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate Range 1.56-100 ng/ml

Mouse/Human Phospho-ETK / BMX (Tyr40) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1252 from LifeSpan Bioscience Category ELISA Kit Prices $550.00 Sizes 1 plate Range 1.56-100 ng/ml

Mouse/Human Phospho-ETK / BMX (Tyr566) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1296 from LifeSpan Bioscience Category ELISA Kit Prices $550.00 Sizes 1 plate Range 1.56-100 ng/ml

Mouse/Human ETK / BMX ELISA Kit (Cell-Based ELISA) - LS-F1978 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate Range 1.56-100 ng/ml

Human ETK / BMX ELISA Kit (Sandwich ELISA) - LS-F10955 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 1.56 Range 1.56-100 ng/ml

Phosphotyrosine BMX / Cytoplasmic Tyrosine-protein Kinase BMX ELISA Kit - RAB0937 from Sigma-Aldrich Category ELISA Kit Prices $637.00 Sizes 1 kt

Cytoplasmic tyrosine-protein kinase BMX (BMX), Human, ELISA Kit - E01C1218 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

Cytoplasmic tyrosine-protein kinase BMX, BMX, Human, ELISA Kit - E2227h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 1.56-100 ng/mL

Ephrin Type A Receptor 3 (EPHA3), Human, ELISA Kit - SEE123Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 0.108ng/mL Range 0.312-20ng/mL

ETK Colorimetric Cell-Based ELISA Kit - CB5251 from Assay Biotechnology Category ELISA Kit Prices $380.00, $760.00, $1,140.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

BMX Colorimetric Cell-Based ELISA - CB5909 from Assay Biotechnology Category ELISA Kit Prices $380.00, $760.00, $1,140.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

ETK (Phospho-Tyr40) Colorimetric Cell-Based ELISA Kit - CBP1252 from Assay Biotechnology Category ELISA Kit Prices $480.00, $960.00, $1,440.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

ETK (Phospho-Tyr566) Colorimetric Cell-Based ELISA Kit - CBP1300 from Assay Biotechnology Category ELISA Kit Prices $480.00, $960.00, $1,440.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

Cytoplasmic tyrosine protein kinase BMX (BMX), ELISA Kit - MBS7210245 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cytoplasmic tyrosine-protein kinase BMX (BMX), ELISA Kit - MBS7202562 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cytoplasmic tyrosine-protein kinase BMX (BMX), ELISA Kit - MBS7210780 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cytoplasmic tyrosine-protein kinase BMX (BMX), ELISA Kit - MBS7232034 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cytoplasmic tyrosine-protein kinase BMX (BMX), ELISA Kit - MBS7220520 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cytoplasmic tyrosine-protein kinase BMX (BMX), ELISA Kit - MBS7234605 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cytoplasmic tyrosine-protein kinase BMX (BMX), ELISA Kit - MBS7218236 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cytoplasmic tyrosine-protein kinase BMX (BMX), ELISA Kit - MBS7226249 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cytoplasmic tyrosine-protein kinase BMX (BMX), ELISA Kit - MBS7243411 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cytoplasmic tyrosine-protein kinase BMX (BMX), ELISA Kit - MBS7241135 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cytoplasmic tyrosine-protein kinase BMX (BMX), ELISA Kit - MBS7249083 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cytoplasmic tyrosine-protein kinase BMX (BMX), ELISA Kit - MBS7224805 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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