DLX5

Gene Symbol	DLX5
Entrez Gene	1749
Alt Symbol	SHFM1D
Species	Human
Gene Type	protein-coding
Description	distal-less homeobox 5
Other Description	distal-less homeo box 5|homeobox protein DLX-5|split hand/foot malformation type 1 with sensorineural hearing loss
Swissprots	B7Z4P3 Q9UPL1 P56178
Accessions	AAC17833 EAL24121 EAW76741 P56178 AA129308 AK023493 BAB14587 AK297614 BAH12629 BC006226 AAH06226 BT006903 AAP35549 DB280023 XM_005250185 XP_005250242 XM_011515860 XP_011514162 XR_927389 NM_005221 NP_005212
Function	Transcriptional factor involved in bone development. Acts as an immediate early BMP-responsive transcriptional activator essential for osteoblast differentiation. Stimulates ALPL promoter activity in a RUNX2-independent manner during osteoblast differentiation. Stimulates SP7 promoter activity during osteoblast differentiation. Promotes cell proliferation by up-regulating MYC promoter activity. Involved as a positive regulator of both chondrogenesis and chondrocyte hypertrophy in the endochondral skeleton. Binds to the homeodomain-response element of the ALPL and SP7 promoter. Binds to the MYC promoter. Requires the 5'-TAATTA-3' consensus sequence for DNA-binding. {ECO:0000269|PubMed:19497851}.
Subcellular Location	Nucleus {ECO:0000255|PROSITE- ProRule:PRU00108}.
Top Pathways	Signaling pathways regulating pluripotency of stem cells

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Mouse/Human/Rat DLX5 ELISA Kit (Cell-Based ELISA) - LS-F3136 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate

Mouse/Human/Rat DLX5 ELISA Kit (DNA-Binding ELISA) - LS-F745 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate

DLX5 Colorimetric Cell-Based ELISA - CB5930 from Assay Biotechnology Category ELISA Kit Prices $380.00, $760.00, $1,140.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

DLX5 TFact™ DNA-Binding ELISA - TFE-7039 from Assay Biotechnology Category ELISA Kit Prices $495.00, $990.00, $1,485.00 Sizes 1 kit, 2 kits, 3 kits

Distal less Homeobox 5, ELISA Kit - MBS752385 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Distal less Homeobox 5, ELISA Kit - MBS753466 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Distal less Homeobox 5, ELISA Kit - MBS726843 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Distal less Homeobox 5, ELISA Kit - MBS749424 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Distal less Homeobox 5, ELISA Kit - MBS751494 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Distal less Homeobox 5, ELISA Kit - MBS755590 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 1.0 pg/mL.

Distal less Homeobox 5, ELISA Kit - MBS749469 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Distal less Homeobox 5, ELISA Kit - MBS751010 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Distal less Homeobox 5, ELISA Kit - MBS753837 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Distal less Homeobox 5, ELISA Kit - MBS745650 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 1.0 pg/mL.

Distal less Homeobox 5, ELISA Kit - MBS746427 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Distal less Homeobox 5, ELISA Kit - MBS744391 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 1.0 pg/mL.

distal-less homeobox 5 - MBS9329454 from MyBioSource Category ELISA Kit Prices $435.00, $600.00 Sizes 48 strip wells, 96 strip wells

DLX5 ELISA Kit - DEIA-XYA550 from Creative Diagnostics Category ELISA Kit

DLX5 ELISA Kit - DEIA-XYA551 from Creative Diagnostics Category ELISA Kit

Human DLX5 ELISA Kit - E012078 from Biobool Category ELISA Kit Sensitivity 1.0 pg/mL.

anti-DLX5 antibody - ARG64916 from Arigo Biolaboratories Category ELISA Kit

Distal Less Homeobox 5 (DLX5), ELISA Kit - MBS9370673 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

DLX5 Colorimetric Cell-Based ELISA Kit - EKA50786 from Biomatik Category ELISA Kit Prices $399.00 Sizes 96 tests Sensitivity At least 5000 cells/well Range Qualitative

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