DLX5

Gene Symbol DLX5
Entrez Gene 1749
Alt Symbol SHFM1D
Species Human
Gene Type protein-coding
Description distal-less homeobox 5
Other Description distal-less homeo box 5|homeobox protein DLX-5|split hand/foot malformation type 1 with sensorineural hearing loss
Swissprots B7Z4P3 Q9UPL1 P56178
Accessions AAC17833 EAL24121 EAW76741 P56178 AA129308 AK023493 BAB14587 AK297614 BAH12629 BC006226 AAH06226 BT006903 AAP35549 DB280023 XM_005250185 XP_005250242 XM_011515860 XP_011514162 XR_927389 NM_005221 NP_005212
Function Transcriptional factor involved in bone development. Acts as an immediate early BMP-responsive transcriptional activator essential for osteoblast differentiation. Stimulates ALPL promoter activity in a RUNX2-independent manner during osteoblast differentiation. Stimulates SP7 promoter activity during osteoblast differentiation. Promotes cell proliferation by up-regulating MYC promoter activity. Involved as a positive regulator of both chondrogenesis and chondrocyte hypertrophy in the endochondral skeleton. Binds to the homeodomain-response element of the ALPL and SP7 promoter. Binds to the MYC promoter. Requires the 5'-TAATTA-3' consensus sequence for DNA-binding. {ECO:0000269|PubMed:19497851}.
Subcellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00108}.
Top Pathways Signaling pathways regulating pluripotency of stem cells

Dlx-5 CRISPR/Cas9 KO Plasmid (h) - sc-401825 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dlx-5 HDR Plasmid (h) - sc-401825-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dlx-5 Double Nickase Plasmid (h) - sc-401825-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dlx-5 Double Nickase Plasmid (h2) - sc-401825-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dlx-5 CRISPR Activation Plasmid (h) - sc-401825-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dlx-5 CRISPR Activation Plasmid (h2) - sc-401825-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dlx-5 Lentiviral Activation Particles (h) - sc-401825-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dlx-5 Lentiviral Activation Particles (h2) - sc-401825-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dlx-5 siRNA (h) - sc-38657 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Dlx-5 shRNA Plasmid (h) - sc-38657-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Dlx-5 shRNA (h) Lentiviral Particles - sc-38657-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU022041 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN7304 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7304 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR02690 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr02690

DLX5 siRNA (Human) - CRH1216 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

DLX5 RNAi - H00001749-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

DLX5 - MBS8204088 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human DLX5 (NM_005221.5) - SHH278717 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human DLX5(NM_005221.5) - SHH007571 from Creative biogene

Category siRNA
Species Reactivities Human

Human DLX5 siRNA - orb261718 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

DLX5 shRNA Plasmid (Human) - CHH1216 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

DLX5 miRNA 3'UTR clone - MiUTR1H-02876 from Creative biogene

Species Reactivities Human
Search more