DLX5

Gene Symbol	DLX5
Entrez Gene	1749
Alt Symbol	SHFM1D
Species	Human
Gene Type	protein-coding
Description	distal-less homeobox 5
Other Description	distal-less homeo box 5|homeobox protein DLX-5|split hand/foot malformation type 1 with sensorineural hearing loss
Swissprots	B7Z4P3 Q9UPL1 P56178
Accessions	AAC17833 EAL24121 EAW76741 P56178 AA129308 AK023493 BAB14587 AK297614 BAH12629 BC006226 AAH06226 BT006903 AAP35549 DB280023 XM_005250185 XP_005250242 XM_011515860 XP_011514162 XR_927389 NM_005221 NP_005212
Function	Transcriptional factor involved in bone development. Acts as an immediate early BMP-responsive transcriptional activator essential for osteoblast differentiation. Stimulates ALPL promoter activity in a RUNX2-independent manner during osteoblast differentiation. Stimulates SP7 promoter activity during osteoblast differentiation. Promotes cell proliferation by up-regulating MYC promoter activity. Involved as a positive regulator of both chondrogenesis and chondrocyte hypertrophy in the endochondral skeleton. Binds to the homeodomain-response element of the ALPL and SP7 promoter. Binds to the MYC promoter. Requires the 5'-TAATTA-3' consensus sequence for DNA-binding. {ECO:0000269|PubMed:19497851}.
Subcellular Location	Nucleus {ECO:0000255|PROSITE- ProRule:PRU00108}.
Top Pathways	Signaling pathways regulating pluripotency of stem cells

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Dlx5 full length protein - ab40537 from Abcam Category Protein Source E. coli Species Human

Human Dlx5 peptide - ab26294 from Abcam Category Peptide

DLX5 Antibody Blocking Peptide - LS-E3213 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

DLX5 Antibody Blocking Peptide - LS-E11046 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

DLX5 Antibody Blocking Peptide - LS-E13883 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

DLX5 Antibody Blocking Peptide - LS-E13884 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

DLX5 Antibody Blocking Peptide - LS-E27032 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human DLX5 Protein - H00001749-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

DLX5-Antibody-Center-Blocking-Peptide - BP14365c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

DLX5 blocking peptide - GTX88434-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Rat, Bovine

DLX5 Blocking Peptide - abx062540 from Abbexa Category Peptide Species Human, Mouse, Rat, Chicken, Zebrafish

DLX5 Peptide - AC21-1855-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

DLX5 - H00001749-P01-02 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Source in vitro transl. Species Human

DLX5 - H00001749-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

DLX5 - H00001749-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

DLX5 Peptide - 46-983P from ProSci Category Peptide Species Human

DLX5 fusion protein - Ag0910 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

DLX5 fusion protein - Ag17040 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human Distal-less Homeobox 5, His-tagged - DLX5-2926H from Creative Biomart Category Protein Source E.coli .

DLX5 Blocking Peptide - CBP1346 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat, Chicken, Zebrafish

Dlx-5 (E126) Peptide - BS2022P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Human Homeobox protein DLX-5(DLX5) - CSB-YP006956HU CSB-EP006956HU CSB-BP006956HU CSB-MP006956HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

DLX5, Peptide - MBS426946 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse, Rat, Bovine

Recombinant Human DLX5 protein, GST-tagged - DLX5-28H from Creative Biomart Category Protein Source Wheat Germ Species Human

DLX5 Recombinant Protein Antigen - NBP1-85793PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

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