DLX5

Gene Symbol	DLX5
Entrez Gene	1749
Alt Symbol	SHFM1D
Species	Human
Gene Type	protein-coding
Description	distal-less homeobox 5
Other Description	distal-less homeo box 5|homeobox protein DLX-5|split hand/foot malformation type 1 with sensorineural hearing loss
Swissprots	B7Z4P3 Q9UPL1 P56178
Accessions	AAC17833 EAL24121 EAW76741 P56178 AA129308 AK023493 BAB14587 AK297614 BAH12629 BC006226 AAH06226 BT006903 AAP35549 DB280023 XM_005250185 XP_005250242 XM_011515860 XP_011514162 XR_927389 NM_005221 NP_005212
Function	Transcriptional factor involved in bone development. Acts as an immediate early BMP-responsive transcriptional activator essential for osteoblast differentiation. Stimulates ALPL promoter activity in a RUNX2-independent manner during osteoblast differentiation. Stimulates SP7 promoter activity during osteoblast differentiation. Promotes cell proliferation by up-regulating MYC promoter activity. Involved as a positive regulator of both chondrogenesis and chondrocyte hypertrophy in the endochondral skeleton. Binds to the homeodomain-response element of the ALPL and SP7 promoter. Binds to the MYC promoter. Requires the 5'-TAATTA-3' consensus sequence for DNA-binding. {ECO:0000269|PubMed:19497851}.
Subcellular Location	Nucleus {ECO:0000255|PROSITE- ProRule:PRU00108}.
Top Pathways	Signaling pathways regulating pluripotency of stem cells

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human-DLX5-cDNA-Clone - DC01902 from Abgent, a WuXi AppTec company Prices $390.15 Sizes 10 µg Species Human Accession BC006226

DLX5 - MBS1267390 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC006226

Human DLX5 cDNA clone(NM_005221.5) - CDFH005173 from Creative Biomart Species Human Accession NM_005221.5

Human DLX5 ORF Clone(NM_005221.5) - CDCR289924 from Creative Biomart Species Human Accession NM_005221.5

Human DLX5 ORF Clone(NM_005221.5) - CDCR289925 from Creative Biomart Species Human Accession NM_005221.5

Human DLX5 ORF Clone(NM_005221.5) - CDCR289926 from Creative Biomart Species Human Accession NM_005221.5

Human DLX5 ORF Clone(NM_005221.5) - CDCL161193 from Creative Biomart Species Human Accession NM_005221.5

Human DLX5 Gene ORF cDNA clone in cloning vector - HG14627-G from Sino Biological Species Human

Human DLX5 Gene ORF cDNA clone expression plasmid - HG14627-UT from Sino Biological Species Human

Human DLX5 Gene ORF cDNA clone expression plasmid, C-HA tag - HG14627-CY from Sino Biological Species Human

Human DLX5 Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG14627-ANG from Sino Biological Species Human

Human DLX5 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG14627-ACR from Sino Biological Species Human

Human DLX5 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG14627-NF from Sino Biological Species Human

Human DLX5 Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG14627-ANR from Sino Biological Species Human

Human DLX5 Gene ORF cDNA clone expression plasmid, N-His tag - HG14627-NH from Sino Biological Species Human

Human DLX5 Gene ORF cDNA clone expression plasmid, N-HA tag - HG14627-NY from Sino Biological Species Human

Human DLX5 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG14627-ACG from Sino Biological Species Human

Human DLX5 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG14627-CF from Sino Biological Species Human

Human DLX5 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG14627-CM from Sino Biological Species Human

Human DLX5 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG14627-NM from Sino Biological Species Human

Human DLX5 Gene ORF cDNA clone expression plasmid, C-His tag - HG14627-CH from Sino Biological Species Human

Human DLX5 ORF Clone(NM_005221.5) - CDCR289924 from Creative biogene Species Human

Human DLX5 ORF Clone (BC006226) - CDCS412150 from Creative biogene Species Human Accession P56178

Human DLX5 ORF clone (BC006226) - CDCB158881 from Creative biogene Species Human

Human DLX5 cDNA Clone(NM_005221.5) - CDFH005173 from Creative biogene Species Human

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