IMPDH2

Gene Symbol	IMPDH2
Entrez Gene	3615
Alt Symbol	IMPD2, IMPDH-II
Species	Human
Gene Type	protein-coding
Description	IMP (inosine 5'-monophosphate) dehydrogenase 2
Other Description	IMP (inosine monophosphate) dehydrogenase 2|IMP oxireductase 2|IMPD 2|IMPDH 2|inosine 5' phosphate dehydrogenase 2|inosine monophosphate dehydrogenase type II|inosine-5'-monophosphate dehydrogenase 2
Swissprots	P12268 Q6LEF3
Accessions	AAA36113 AAA67054 AAB70699 AAR84630 AAR84631 AAR84632 CBX53836 EAW64946 EAW64947 P12268 AK293397 BAH11500 AY545560 AAS50155 BC006124 AAH06124 BC009236 BC012840 AAH12840 BC015567 AAH15567 DQ893403 ABM84329 DQ896721 ABM87720 J04208 AAA36112 XM_006713128 XP_006713191 NM_000884 NP_000875
Function	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.
Subcellular Location	Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03156, ECO:0000269|PubMed:14766016}. Nucleus {ECO:0000255|HAMAP- Rule:MF_03156, ECO:0000269|PubMed:14766016}.
Tissue Specificity	IMP type I is the main species in normal leukocytes and type II predominates over type I in the tumor.
Top Pathways	Purine metabolism, Drug metabolism - other enzymes

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human IMPDH2 ELISA Kit (Sandwich ELISA) - LS-F9663 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 0.27 ng/ml Range 0.781-50 ng/ml

Human IMPDH2 ELISA Kit - abx151966 from Abbexa Category ELISA Kit Sensitivity 0.27 ng/ml Range 0.781 ng/ml - 50 ng/ml

Inosine-5'-monophosphate dehydrogenase 2 (IMPDH2), Human, ELISA Kit - CSB-E17855h from ARP American Research Products Category ELISA Kit Prices $550.00, $790.00, $791.00, $794.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

IMPDH2 (Human) IP-WB Antibody Pair - H00003615-PW1 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

IMP (inosine monophosphate) dehydrogenase 2, ELISA Kit - MBS906235 from MyBioSource Category ELISA Kit Prices $250.00, $550.00, $795.00, $2,890.00, $5,465.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 5.8 pg/ml Range 23.5 pg/ml-1500 pg/ml

Inosine 5'-Monophosphate Dehydrogenase 2 (IMPDH2), ELISA Kit - MBS2000373 from MyBioSource Category ELISA Kit Prices $380.00, $565.00, $765.00, $3,130.00, $5,670.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity Typically less than 0.27ng/mL. Range 0.781-50ng/mL

ELISA Kit for Inosine 5'-Monophosphate Dehydrogenase 2 (IMPDH2) - SEF632Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.27ng/mL. Range 0.781-50ng/mL The standard curve concentrations used for the ELISA’s were 50ng/mL, 25ng/mL, 12.5ng/mL, 6.25ng/mL, 3.125ng/mL, 1.563ng/mL, 0.781ng/mL

Human Inosine-5'-monophosphate dehydrogenase 2 (IMPDH2) ELISA kit - CSB-E17855h from Cusabio Category ELISA Kit Sensitivity 5.8 pg/ml Range 23.5 pg/ml-1500 pg/ml

ELISA Kit for Inosine 5'-Monophosphate Dehydrogenase 2 (IMPDH2) - SEF632Hu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.27ng/mL. Range 0.781-50ng/mL The standard curve concentrations used for the ELISA's were 50ng/mL, 25ng/mL, 12.5ng/mL, 6.25ng/mL, 3.125ng/mL, 1.563ng/mL, 0.781ng/mL

Human IMPDH2 ELISA Kit - abx573656 from Abbexa Category ELISA Kit Sensitivity 0.27 ng/ml Range 0.781 ng/ml - 50 ng/ml

Human Inosine-5'-monophosphate dehydrogenase 2 (IMPDH2) ELISA Kit - EKC34134 from Biomatik Category ELISA Kit Prices $795.00, $3,021.00, $5,645.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 5.8 pg/ml Range 23.5 pg/ml-1500 pg/ml

IMPDH2 - EKH8006 from Nordic BioSite Sensitivity 0.469ng/ml Range 0.781-50ng/ml

Human IMPDH2 ELISA Kit - E019667 from Biobool Category ELISA Kit Sensitivity 5.8 pg/ml

IMPDH2 ELISA Kit (Human) (OKCD01876) - OKCD01876 from Aviva Systems Biology Category ELISA Kit Prices $545.00 Sizes 96 wells Sensitivity < 0.27 ng/mL Range 0.781 - 50 ng/mL

anti-IMPDH2 antibody - ARG64765 from Arigo Biolaboratories Category ELISA Kit

Inosine 5'-Monophosphate Dehydrogenase 2, ELISA Kit - MBS760434 from MyBioSource Category ELISA Kit Prices $295.00, $390.00, $1,615.00, $3,015.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.469ng/ml Range 0.781-50ng/ml

Inosine 5'-Monophosphate Dehydrogenase 2 (IMPDH2), ELISA Kit - MBS456094 from MyBioSource Category ELISA Kit Prices $415.00, $550.00, $2,425.00, $4,710.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity <0.27ng/mL Range 0.78-50ng/mL

Human IMPDH2 ELISA Kit (Sandwich ELISA) - LS-F32357 from LifeSpan Bioscience Category ELISA Kit Sensitivity 0.094 Range 0.781-50 ng/ml

Human IMPDH2 ELISA Kit - orb406441 from Biorbyt Category ELISA Kit Sensitivity 5.8 pg/ml Range 23.5 pg/ml-1500 pg/ml

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