NDN

Gene Symbol	NDN
Entrez Gene	4692
Alt Symbol	HsT16328, PWCR
Species	Human
Gene Type	protein-coding
Description	necdin, melanoma antigen (MAGE) family member
Other Description	Prader-Willi syndrome chromosome region|necdin|necdin homolog
Swissprots	B2R6Z5 Q99608
Accessions	BAA22660 EAW57610 Q99608 AK129654 AK312779 BAG35642 BC008750 AAH08750 HQ448156 ADQ32637 KJ534888 AHW56528 KJ535010 AHW56649 U35139 AAB39469 NM_002487 NP_002478
Function	Growth suppressor that facilitates the entry of the cell into cell cycle arrest. Functionally similar to the retinoblastoma protein it binds to and represses the activity of cell-cycle- promoting proteins such as SV40 large T antigen, adenovirus E1A, and the transcription factor E2F. Necdin also interacts with p53 and works in an additive manner to inhibit cell growth. Functions also as transcription factor and binds directly to specific guanosine-rich DNA sequences (By similarity). {ECO:0000250}.
Subcellular Location	Perikaryon. Nucleus. Note=Neural perikarya, translocates to the nucleus of postmitotic neurons and interacts with the nuclear matrix.
Tissue Specificity	Almost ubiquitous. Detected in fetal brain, lung, liver and kidney; in adult heart, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, testis, ovary, small intestine and colon. Not detected in peripheral blood leukocytes. In brain, restricted to post- mitotic neurons.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human NDN / Necdin ELISA Kit (Sandwich ELISA) - LS-F8366 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 0.066 ng/ml Range 0.156-10 ng/ml

Human Necdin ELISA Kit - abx152466 from Abbexa Category ELISA Kit Sensitivity 0.066 ng/ml Range 0.156 ng/ml - 10 ng/ml

Necdin (NDN), Human, ELISA Kit - SEJ541Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 0.066ng/mL Range 0.156-10ng/mL

Necdin, NDN, Human, ELISA Kit - E0350h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 0.312-20 ng/mL

NDN (Human) IP-WB Antibody Pair - H00004692-PW1 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

NDN (Human) IP-WB Antibody Pair - H00004692-PW2 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

NDN (Human) IP-WB Antibody Pair - H00004692-PW3 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

NDN (Human) Matched Antibody Pair - H00004692-AP11 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

Necdin, ELISA Kit - MBS068901 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Necdin, ELISA Kit - MBS075058 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Necdin, ELISA Kit - MBS072792 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Necdin, ELISA Kit - MBS082571 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Necdin, ELISA Kit - MBS058531 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Necdin, ELISA Kit - MBS072669 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Necdin, ELISA Kit - MBS075512 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ELISA Kit for Necdin (NDN) - SEJ541Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.066ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA’s were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

ELISA Kit for Necdin (NDN) - SEJ541Hu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.066ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA's were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

Mouse NDN / Necdin ELISA Kit (Custom ELISA) - LS-F14361 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range 0.156-10 ng/ml

Necdin (NDN), ELISA Kit - MBS2023454 from MyBioSource Category ELISA Kit Prices $380.00, $565.00, $765.00, $3,130.00, $5,670.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity Typically less than 0.066ng/mL. Range 0.156-10ng/mL

Human Necdin (NDN) ELISA Kit - EKU06158 from Biomatik Category ELISA Kit Prices $735.00, $3,234.00, $5,880.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 0.066 ng/mL Range 0.156-10 ng/mL

Human Necdin ELISA Kit - abx253822 from Abbexa Category ELISA Kit Range 0.312 ng/ml - 20 ng/ml

Human NDN / Necdin ELISA Kit (Sandwich ELISA) - LS-F13349 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.312 Range 0.156-10 ng/ml

Necdin (NDN), Human, ELISA Kit - DL-NDN-Hu from ARP American Research Products Category ELISA Kit Prices $655.00 Sizes 96 t Range 0.156-10 ng/mL

Human NDN ELISA Kit - abx571403 from Abbexa Category ELISA Kit Sensitivity 0.066 ng/ml Range 0.156 ng/ml - 10 ng/ml

Human Necdin ELISA Kit - EKE53022 from Biomatik Category ELISA Kit Prices $685.40, $2,912.95, $5,483.20 Sizes 96 t, 5x96t, 10x96t Sensitivity The minimum detectable dose of this kit is typically less than 0.1 ng/mL Range 0.312-20 ng/mL

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