NDN

Gene Symbol	NDN
Entrez Gene	4692
Alt Symbol	HsT16328, PWCR
Species	Human
Gene Type	protein-coding
Description	necdin, melanoma antigen (MAGE) family member
Other Description	Prader-Willi syndrome chromosome region|necdin|necdin homolog
Swissprots	B2R6Z5 Q99608
Accessions	BAA22660 EAW57610 Q99608 AK129654 AK312779 BAG35642 BC008750 AAH08750 HQ448156 ADQ32637 KJ534888 AHW56528 KJ535010 AHW56649 U35139 AAB39469 NM_002487 NP_002478
Function	Growth suppressor that facilitates the entry of the cell into cell cycle arrest. Functionally similar to the retinoblastoma protein it binds to and represses the activity of cell-cycle- promoting proteins such as SV40 large T antigen, adenovirus E1A, and the transcription factor E2F. Necdin also interacts with p53 and works in an additive manner to inhibit cell growth. Functions also as transcription factor and binds directly to specific guanosine-rich DNA sequences (By similarity). {ECO:0000250}.
Subcellular Location	Perikaryon. Nucleus. Note=Neural perikarya, translocates to the nucleus of postmitotic neurons and interacts with the nuclear matrix.
Tissue Specificity	Almost ubiquitous. Detected in fetal brain, lung, liver and kidney; in adult heart, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, testis, ovary, small intestine and colon. Not detected in peripheral blood leukocytes. In brain, restricted to post- mitotic neurons.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Ndn (N-20) - sc-18255 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Ndn (C-12) - sc-34492 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Ndn (36-V) - sc-101224 from Santa Cruz Biotechnology Prices $295.00 Sizes 100 µg/ml Host Mouse Clonality Monoclonal

Anti-Necdin antibody - ab94529 from Abcam Prices $370.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-Necdin antibody - ab55501 from Abcam Prices $370.00 Sizes 100 µg Host Mouse Clonality Monoclonal

Anti-Necdin antibody [1B3] - ab125108 from Abcam Prices $464.00 Sizes 50 µg Host Mouse Clonality Monoclonal Clone 1B3

Anti-Necdin antibody [3A12] - ab180373 from Abcam Prices $357.00 Sizes 100 µl Host Mouse Clonality Monoclonal Clone 3A12

Anti-Necdin antibody - ChIP Grade - ab18554 from Abcam Prices $380.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-Necdin antibody - N-terminal - ab202378 from Abcam Prices $359.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-NDN / Necdin Antibody (aa1-143) - LS-C37480 from LifeSpan Bioscience Prices $515.00 Sizes 200 µg Host Rabbit Clonality Polyclonal

Anti-NDN / Necdin Antibody (aa42-71, AP) - LS-C223415 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-NDN / Necdin Antibody (aa42-71, APC) - LS-C223417 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-NDN / Necdin Antibody (aa42-71, Biotin) - LS-C223418 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-NDN / Necdin Antibody (aa42-71, FITC) - LS-C223419 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-NDN / Necdin Antibody (aa42-71, Azide-free, HRP) - LS-C223420 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-NDN / Necdin Antibody (aa42-71, PE) - LS-C223422 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-NDN / Necdin Antibody (aa42-71) - LS-C323259 from LifeSpan Bioscience Prices $345.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-NDN / Necdin Antibody (aa179-228) - LS-C111898 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-NDN / Necdin Antibody (clone 3A12) - LS-C338301 from LifeSpan Bioscience Prices $325.00 Sizes 100 µl Host Mouse Clonality Monoclonal Clone 3A12

Anti-NDN / Necdin Antibody (clone 1B1) - LS-C338306 from LifeSpan Bioscience Prices $325.00 Sizes 100 µl Host Mouse Clonality Monoclonal Clone 1B1

Anti-NDN / Necdin Antibody (aa43-71) - LS-C164787 from LifeSpan Bioscience Prices $295.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-NDN / Necdin Antibody (aa75-109) - LS-C344470 from LifeSpan Bioscience Prices $295.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-NDN / Necdin Antibody (clone 5D1) - LS-C338303 from LifeSpan Bioscience Prices $325.00 Sizes 100 µl Host Mouse Clonality Monoclonal Clone 5D1

Anti-NDN / Necdin Antibody (clone 1B3) IHC-plus™ - LS-B6103 from LifeSpan Bioscience Prices $450.00 Sizes 50 µg Host Mouse Clonality Monoclonal Clone 1B3

Necdin Antibody (1B3) - H00004692-M02 from Novus Biologicals Prices $359.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 1B3

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