KHSRP

Gene Symbol KHSRP
Entrez Gene 8570
Alt Symbol FBP2, FUBP2, KSRP
Species Human
Gene Type protein-coding
Description KH-type splicing regulatory protein
Other Description FUSE binding protein 2|FUSE-binding protein 2|KH type-splicing regulatory protein|far upstream element-binding protein 2|p75
Swissprots Q92945 Q9UNT5 O00301 Q5U4P6 Q9UQH5 Q59EZ9
Accessions AAD29861 AAD29862 EAW69095 EAW69096 EAW69097 Q92945 AA976482 AB209662 BAD92899 AK300957 BAG62585 BC009473 BC085004 AAH85004 BQ186683 CB216491 CF123311 DC388502 U69126 AAC50892 U94832 AAB53222 XM_005259668 XP_005259725 XM_011528395 XP_011526697 NM_003685 NP_003676
Function Binds to the dendritic targeting element and may play a role in mRNA trafficking (By similarity). Part of a ternary complex that binds to the downstream control sequence (DCS) of the pre-mRNA. Mediates exon inclusion in transcripts that are subject to tissue-specific alternative splicing. May interact with single- stranded DNA from the far-upstream element (FUSE). May activate gene expression. Also involved in degradation of inherently unstable mRNAs that contain AU-rich elements (AREs) in their 3'- UTR, possibly by recruiting degradation machinery to ARE- containing mRNAs. {ECO:0000250, ECO:0000269|PubMed:11003644, ECO:0000269|PubMed:8940189, ECO:0000269|PubMed:9136930}.
Subcellular Location Nucleus {ECO:0000269|PubMed:19198587}. Cytoplasm {ECO:0000269|PubMed:19198587}. Note=A small proportion is also found in the cytoplasm of neuronal cell bodies and dendrites. {ECO:0000250}.
Tissue Specificity Detected in neural and non-neural cell lines.

KHSRP (E2E2U) Rabbit mAb - 13398 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone E2E2U
Western blot analysis of extracts from various cell lines using KHSRP (E2E2U) Rabbit mAb.

KHSRP Antibody - 5398 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from various cell types using KHSRP Antibody.

FBP2 (D-12) - sc-33031 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
FBP2 (D-12): sc-33031. Western blot analysis of FBP2 expression in non-transfected 293T: sc-117752 (A), mouse FBP2 transfected 293T: sc-178603 (B), HL-60 (C) and A-673 (D) whole cell lysates.

FBP2 (H-40) - sc-367530 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
FBP2 (H-40): sc-367530. Western blot analysis of FBP2 expression in NIH/3T3 whole cell lysate.

FBP2 (S-18) - sc-33032 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
FBP2 (S-18): sc-33032. Western blot analysis of FBP2 expression in non-transfected 293T: sc-117752 (A) and mouse FBP2 transfected 293T: sc-178603 (B) whole cell lysates.

Anti-KHSRP antibody - ab56438 from Abcam

Host Mouse
Clonality Monoclonal
KHSRP antibody (ab56438) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human liver.

Anti-KHSRP antibody [EPR9864] - ab150393 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR9864
All lanes : Anti-KHSRP antibody [EPR9864] (ab150393) at 1/1000 dilutionLane 1 : 293T cell lysateLane 2 : HeLa cell lysateLane 3 : A673 cell lysateLane 4 : MCF7 cell lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled Goat ani-Rabbit at 1/2000 dilution

Anti-KHSRP antibody [EPR9865] - ab140648 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR9865
Overlay histogram showing Hela cells stained with ab140648 (red line). The cells were fixed with 80% methanol (5 min) and then permeabilized with 0.1% PBS-Tween for 20 min. The cells were then incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions followed by the antibody (ab140648, 1/1000 dilution) for 30 min at 22°C. The secondary antibody used was Alexa Fluor® 488 goat anti-rabbit IgG (H&L) (ab150077) at 1/2000 dilution for 30 min at 22°C. Isotype control antibody (black line) was rabbit IgG (monoclonal) (0.1μg/1x106 cells) used under the same conditions. Unlabelled sample (blue line) was also used as a control. Acquisition of >5,000 events were collected using a 20mW Argon ion laser (488nm) and 525/30 bandpass filter. This antibody gave a positive signal in HeLa cells fixed with 4% paraformaldehyde (10 min)/permeabilized with 0.1% PBS-Tween for 20 min used under the same conditions.

Anti-KHSRP antibody - N-terminal - ab135789 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-KHSRP antibody - N-terminal (ab135789) at 1/100 dilution + T47D cell line lysates at 35 µg

Anti-KHSRP / FBP2 Antibody (N-Terminus, AP) - LS-C219861 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KHSRP / FBP2 Antibody (N-Terminus, Biotin) - LS-C219863 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KHSRP / FBP2 Antibody (N-Terminus, APC) - LS-C219862 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KHSRP / FBP2 Antibody (N-Terminus, FITC) - LS-C219864 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KHSRP / FBP2 Antibody (N-Terminus, Azide-free, HRP) - LS-C219865 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KHSRP / FBP2 Antibody (C-Terminus) - LS-C101846 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
KHSRP antibody LS-C101846 Western blot of 293T cell lysate.

Anti-KHSRP / FBP2 Antibody (aa285-334) - LS-C186681 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of Human Thyroid Tumor. KHSRP antibody dilution 1.0 ug/ml.

Anti-KHSRP / FBP2 Antibody (N-Terminus) - LS-C327714 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KHSRP / KSRP Antibody (aa151-240, Azide-free) - LS-C327712 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-KHSRP / FBP2 Antibody (aa100-150) - LS-C288777 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human and Mouse KSRP by Immunohistochemistry. Sample: FFPE section of human colon carcinoma (left) and mouse squamous cell carcinoma (right). Antibody: Affinity purified rabbit anti-KSRP used at a dilution of 1:1000 (0.2 Detection: DAB.

Anti-KHSRP / FBP2 Antibody (aa660-710) - LS-C288779 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human KSRP by Immunohistochemistry. Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti-KSRP used at a dilution of 1:1000 (1 Detection: DAB.

Anti-KHSRP / FBP2 Antibody (clone 4H7) - LS-C133557 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4H7
Immunoperoxidase of monoclonal antibody to KHSRP on formalin-fixed paraffin-embedded human esophagus. [antibody concentration 3 ug/ml]

Anti-KHSRP / FBP2 Antibody (N-Terminus, PE) - LS-C219866 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KHSRP / KSRP Antibody - LS-C334474 from LifeSpan Bioscience

Prices $315.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cell lines, using KHSRP antibody.

Anti-KHSRP / FBP2 Antibody (aa100-150) - LS-C286794 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Mouse KSRP by Immunohistochemistry. Sample: FFPE section of mouse teratoma. Antibody: Affinity purified rabbit anti-KSRP used at a dilution of 1:100.

Anti-KHSRP / FBP2 Antibody (clone 4C10) IHC-plus™ - LS-B4471 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 4C10
Anti-KHSRP antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4471 concentration 5 ug/ml.
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