CTDSP1

Gene Symbol CTDSP1
Entrez Gene 58190
Alt Symbol NIF3, NLI-IF, NLIIF, SCP1
Species Human
Gene Type protein-coding
Description CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
Other Description NLI-interacting factor 3|carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1|nuclear LIM interactor-interacting factor 3|small C-terminal domain phosphatase 1
Swissprots Q7Z5Q4 Q9GZU7 C9IYG0 Q7Z5Q3
Accessions AAG15404 EAW70615 EAW70616 EAW70617 EAW70618 Q9GZU7 AF217969 AAG17212 AF229162 AAG15402 AF258582 AAG23785 AK075090 AY279529 AAP34397 AY279530 AAP34398 BC012977 AAH12977 BX424971 BX446444 EU446878 ABZ92407 XM_011511569 XP_011509871 XM_011511570 XP_011509872 NM_001206878 NP_001193807 NM_021198 NP_067021 NM_182642 NP_872580 NM_001206879
Function Preferentially catalyzes the dephosphorylation of 'Ser- 5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells. {ECO:0000269|PubMed:12721286, ECO:0000269|PubMed:15681389}.
Subcellular Location Nucleus {ECO:0000269|PubMed:12721286}. Note=Colocalizes with RNA polymerase II.
Tissue Specificity Expression is restricted to non-neuronal tissues. Highest expression in skeletal muscle, spleen, lung and placenta. {ECO:0000269|PubMed:15681389}.

CTDSP1 (D-14) - sc-107346 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CTDSP1 (D-14): sc-107346. Western blot analysis of CTDSP1 expression in A-673 (A) and JAR (B) whole cell lysates.

Anti-CTDSP1 antibody - ab130144 from Abcam

Prices $370.00
Sizes 200 µl
Host Goat
Clonality Polyclonal
ab130144 (5µg/ml) shows staining of CTDSP1 in paraffin embedded Human Tonsil following steamed antigen retrieval with citrate buffer pH 6 and AP-staining. This shows nucleolar staining in select cells outside the follicles.

Anti-CTDSP1 antibody - ab134311 from Abcam

Prices $407.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human uterus tissue labelling CTDSP1 with ab134311 at 5 µg/ml.

Anti-CTDSP1 antibody - ab136038 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-CTDSP1 antibody (ab136038) at 1/500 dilution + HepG2 cell lysate at 30 µg

Anti-CTDSP1 antibody - ab130718 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-CTDSP1 antibody (ab130718) at 1/100 dilution + Jurkat cell lysate at 35 µg

Anti-CTDSP1 antibody - ab130953 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-CTDSP1 antibody (ab130953) at 1 µg/ml + Jurkat cell lysate at 10 µg

Anti-CTDSP1 antibody [1F4] - ab117868 from Abcam

Prices $370.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1F4
All lanes : Anti-CTDSP1 antibody [1F4] (ab117868) at 1/500 dilutionLane 1 : HEK293T cells transfected with pCMV6-ENTRY control Lane 2 : HEK293T cells transfected with pCMV6-ENTRY CTDSP1 cDNA Lysates/proteins at 5 µg per lane.

Anti-CTDSP1 antibody - C-terminal - ab76099 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-CTDSP1 antibody - C-terminal (ab76099) at 1/100 dilution + CEM tissue lysate at 12.5 µg

Anti-CTDSP1 / SCP1 Antibody (aa16-50) - LS-C344368 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Western blot of lysates from HepG2 cell line, mouse liver tissue lysate (from left to right) with CTDSP1 Antibody. Antibody was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L (HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20 ug per lane.

Anti-CTDSP1 / SCP1 Antibody (clone 1A10) - LS-C172552 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone 1A10
Anti-CTDSP1 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY CTDSP1.

Anti-CTDSP1 / SCP1 Antibody (Internal) IHC-plus™ - LS-B9498 from LifeSpan Bioscience

Host Goat
Clonality Polyclonal
Anti-CTDSP1 / SCP1 antibody IHC staining of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-CTDSP1 / SCP1 Antibody (aa96-130) - LS-C344482 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Western blot of lysates from HepG2, Jurkat cell line, mouse liver tissue lysate (from left to right) with CTDSP1 Antibody. Antibody was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L (HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20 ug per lane.

Anti-CTDSP1 / SCP1 Antibody (clone 1D3) - LS-C337214 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone 1D3
Anti-CTDSP1 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY CTDSP1.

Anti-CTDSP1 / SCP1 Antibody (clone 1G1) - LS-C337226 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone 1G1
IHC of paraffin-embedded Human thyroid tissue using anti-CTDSP1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).

Anti-CTDSP1 / SCP1 Antibody (clone 1B6) - LS-C172536 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone 1B6
IHC of paraffin-embedded Carcinoma of Human prostate tissue using anti-CTDSP1 mouse monoclonal antibody.

Anti-CTDSP1 / SCP1 Antibody (aa22-71) - LS-C151879 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
CTDSP1 / SCP1 antibody Western Blot of Jurkat.

Anti-CTDSP1 / SCP1 Antibody (aa72-121) - LS-C151880 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
CTDSP1 / SCP1 antibody Western Blot of HepG2.

Anti-CTDSP1 / SCP1 Antibody (aa1-30) - LS-C167122 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
CTDSP1 Antibody western blot of Jurkat cell line lysates (35 ug/lane). The CTDSP1 antibody detected the CTDSP1 protein (arrow).

Anti-CTDSP1 / SCP1 Antibody (clone 1A7) - LS-C172528 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone 1A7
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CTDSP1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CTDSP1.

Anti-CTDSP1 / SCP1 Antibody (aa1-50) - LS-C119822 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded human breast carcinoma tissue, using CTDSP1 Antibody. The picture on the right is treated with the synthesized peptide.

Anti-CTDSP1 / SCP1 Antibody (aa1-30, AP) - LS-C255615 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CTDSP1 / SCP1 Antibody (aa1-30, FITC) - LS-C255618 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CTDSP1 / SCP1 Antibody (aa1-30, Biotin) - LS-C255617 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CTDSP1 / SCP1 Antibody (aa1-30, APC) - LS-C255616 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CTDSP1 / SCP1 Antibody (aa1-30, PE) - LS-C255620 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
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