CTDSP1

Gene Symbol	CTDSP1
Entrez Gene	58190
Alt Symbol	NIF3, NLI-IF, NLIIF, SCP1
Species	Human
Gene Type	protein-coding
Description	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
Other Description	NLI-interacting factor 3|carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1|nuclear LIM interactor-interacting factor 3|small C-terminal domain phosphatase 1
Swissprots	Q7Z5Q4 Q9GZU7 C9IYG0 Q7Z5Q3
Accessions	AAG15404 EAW70615 EAW70616 EAW70617 EAW70618 Q9GZU7 AF217969 AAG17212 AF229162 AAG15402 AF258582 AAG23785 AK075090 AY279529 AAP34397 AY279530 AAP34398 BC012977 AAH12977 BX424971 BX446444 EU446878 ABZ92407 XM_011511569 XP_011509871 XM_011511570 XP_011509872 NM_001206878 NP_001193807 NM_021198 NP_067021 NM_182642 NP_872580 NM_001206879
Function	Preferentially catalyzes the dephosphorylation of 'Ser- 5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells. {ECO:0000269|PubMed:12721286, ECO:0000269|PubMed:15681389}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:12721286}. Note=Colocalizes with RNA polymerase II.
Tissue Specificity	Expression is restricted to non-neuronal tissues. Highest expression in skeletal muscle, spleen, lung and placenta. {ECO:0000269|PubMed:15681389}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

CTDSP1-Over-expression-Lysate - LY14495a from Abgent, a WuXi AppTec company Category Cell Lysate Prices $325.00 Sizes 100 µg

CTDSP1 overexpression lysate - LY403640 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

CTDSP1 293 Cell Lysate - 405978 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

CTDSP1 293 Cell Lysate - 403138 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

CTDSP1 Overexpression Lysate (Native) - NBL1-09567 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

CTDSP1 Overexpression Lysate (Native) - NBL1-09566 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

CTDSP1 Over-expression Lysate Product - GWB-70FFDB from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

CTDSP1 Over-expression Lysate Product - GWB-3FFF81 from Genway Biotech Category Cell Lysate Prices $445.00 Sizes 100 µg Species Human

Panoply™ Human CTDSP1 Knockdown Stable Cell Line - CSC-DC003790 from Creative biogene Category Cell Line Species Human

CTDSP1 KO Cell Lysate-HEK293T - CLKO-0791 from Creative biogene Category Cell Lysate

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