| Gene Symbol | CTDSP1 |
|---|---|
| Entrez Gene | 58190 |
| Alt Symbol | NIF3, NLI-IF, NLIIF, SCP1 |
| Species | Human |
| Gene Type | protein-coding |
| Description | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 |
| Other Description | NLI-interacting factor 3|carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1|nuclear LIM interactor-interacting factor 3|small C-terminal domain phosphatase 1 |
| Swissprots | Q7Z5Q4 Q9GZU7 C9IYG0 Q7Z5Q3 |
| Accessions | AAG15404 EAW70615 EAW70616 EAW70617 EAW70618 Q9GZU7 AF217969 AAG17212 AF229162 AAG15402 AF258582 AAG23785 AK075090 AY279529 AAP34397 AY279530 AAP34398 BC012977 AAH12977 BX424971 BX446444 EU446878 ABZ92407 XM_011511569 XP_011509871 XM_011511570 XP_011509872 NM_001206878 NP_001193807 NM_021198 NP_067021 NM_182642 NP_872580 NM_001206879 |
| Function | Preferentially catalyzes the dephosphorylation of 'Ser- 5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells. {ECO:0000269|PubMed:12721286, ECO:0000269|PubMed:15681389}. |
| Subcellular Location | Nucleus {ECO:0000269|PubMed:12721286}. Note=Colocalizes with RNA polymerase II. |
| Tissue Specificity | Expression is restricted to non-neuronal tissues. Highest expression in skeletal muscle, spleen, lung and placenta. {ECO:0000269|PubMed:15681389}. |
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 (CTDSP1), Human, ELISA Kit - E01C2146 from ARP American Research Products
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Carboxy terminal domain RNA polymerase II polypeptide A small phosphatase 1 (CTDSP1), ELISA Kit - MBS7238291 from MyBioSource
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Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1, ELISA Kit - MBS282293 from MyBioSource
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Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 (CTDSP1), ELISA Kit - MBS7232308 from MyBioSource
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Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 (CTDSP1), ELISA Kit - MBS7252826 from MyBioSource
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Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 (CTDSP1), ELISA Kit - MBS7220066 from MyBioSource
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Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 (CTDSP1), ELISA Kit - MBS7224941 from MyBioSource
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Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 (CTDSP1), ELISA Kit - MBS7252591 from MyBioSource
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Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 (CTDSP1), ELISA Kit - MBS7202932 from MyBioSource
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Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 (CTDSP1), ELISA Kit - MBS7208579 from MyBioSource
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Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 (CTDSP1), ELISA Kit - MBS7253166 from MyBioSource
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Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 (CTDSP1), ELISA Kit - MBS7236532 from MyBioSource
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Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 (CTDSP1), ELISA Kit - MBS7213243 from MyBioSource
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Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 (CTDSP1), ELISA Kit - MBS7248105 from MyBioSource
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Human CTDSP1 ELISA Kit - E006544 from Biobool
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anti-CTDSP1 antibody - ARG55219 from Arigo Biolaboratories
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anti-CTDSP1 antibody - ARG55220 from Arigo Biolaboratories
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