PSMD10

Gene Symbol	PSMD10
Entrez Gene	5716
Alt Symbol	dJ889N15.2, p28, p28(GANK)
Species	Human
Gene Type	protein-coding
Description	proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
Other Description	26S proteasome non-ATPase regulatory subunit 10|26S proteasome regulatory subunit p28|ankyrin repeat protein|gankyrin|hepatocellular carcinoma-associated protein p28-II
Swissprots	Q8IZK9 Q5U0B2 O75832
Accessions	CAV33747 EAX02697 EAX02698 O75832 AB009619 BAA33215 AK058108 AK295996 BAG58771 AK309326 AY057056 AAL25260 BC011960 AAH11960 BI114640 BQ217943 BT019689 AAV38495 D83197 BAA34594 GQ129344 ACT64478 GQ129345 ACT64479 R15438 NM_002814 NP_002805 NM_170750 NP_736606
Function	Acts as a chaperone during the assembly of the 26S proteasome, specifically of the PA700/19S regulatory complex (RC). In the initial step of the base subcomplex assembly is part of an intermediate PSMD10:PSMC4:PSMC5:PAAF1 module which probably assembles with a PSMD5:PSMC2:PSMC1:PSMD2 module. Independently of the proteasome, regulates EGF-induced AKT activation through inhibition of the RHOA/ROCK/PTEN pahway, leading to prolonged AKT activation. Plays an important role in RAS-induced tumorigenesis.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:18040287}. Nucleus {ECO:0000269|PubMed:18040287}.
Tissue Specificity	Tends to be up-regulated in cancer cells with RAS mutations, including lung cancers and adenocarconimas (at protein level). {ECO:0000269|PubMed:10613832, ECO:0000269|PubMed:20628200}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human PSMD10 / Gankyrin ELISA Kit (Sandwich ELISA) - LS-F8443 from LifeSpan Bioscience Category ELISA Kit Prices $790.00 Sizes 1 plate Sensitivity 0.059 ng/ml Range 0.156-10 ng/ml

26S proteasome non-ATPase regulatory subunit 10 (PSMD10), Human, ELISA Kit - E01R0155 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

26S proteasome non ATPase regulatory subunit 10 (PSMD10), ELISA Kit - MBS7239282 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

26S proteasome non-ATPase regulatory subunit 10 (PSMD10), ELISA Kit - MBS7217462 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

26S proteasome non-ATPase regulatory subunit 10 (PSMD10), ELISA Kit - MBS7227968 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

26S proteasome non-ATPase regulatory subunit 10 (PSMD10), ELISA Kit - MBS7232597 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

26S proteasome non-ATPase regulatory subunit 10 (PSMD10), ELISA Kit - MBS7200900 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

26S proteasome non-ATPase regulatory subunit 10 (PSMD10), ELISA Kit - MBS7232402 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

26S proteasome non-ATPase regulatory subunit 10 (PSMD10), ELISA Kit - MBS7201941 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

26S proteasome non-ATPase regulatory subunit 10 (PSMD10), ELISA Kit - MBS7239082 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

26S proteasome non-ATPase regulatory subunit 10 (PSMD10), ELISA Kit - MBS7213498 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

26S proteasome non-ATPase regulatory subunit 10 (PSMD10), ELISA Kit - MBS7218642 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

26S proteasome non-ATPase regulatory subunit 10 (PSMD10), ELISA Kit - MBS7210206 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

26S proteasome non-ATPase regulatory subunit 10 (PSMD10), ELISA Kit - MBS7207675 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ELISA Kit for Proteasome 26S Subunit, Non ATPase 10 (PSMD10) - SEP783Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.059ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA’s were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

Human PSMD10 ELISA Kit - abx152877 from Abbexa Category ELISA Kit Sensitivity 0.059 ng/ml Range 0.156 ng/ml - 10 ng/ml

Proteasome 26S Subunit, Non ATPase 10 (PSMD10), Human, ELISA Kit - DL-PSMD10-Hu from ARP American Research Products Category ELISA Kit Prices $655.00 Sizes 96 t Range 0.156-10 ng/mL

Human PSMD10 ELISA Kit - abx571424 from Abbexa Category ELISA Kit Sensitivity 0.059 ng/ml Range 0.156 ng/ml - 10 ng/ml

Human PSMD10 ELISA Kit - E031441 from Biobool Category ELISA Kit Sensitivity Typically less than 0.059ng/mL.

PSMD10 ELISA Kit (Human) (OKCD00632) - OKCD00632 from Aviva Systems Biology Category ELISA Kit Prices $585.00 Sizes 96 wells Sensitivity < 0.059 ng/mL Range 0.156-10 ng/mL

PSMD10 ELISA Kit (Human) (OKDD00491) - OKDD00491 from Aviva Systems Biology Category ELISA Kit Prices $620.00 Sizes 96 wells Sensitivity < 0.059 ng/mL Range 0.156-10 ng/mL

anti-PSMD10 antibody - ARG55597 from Arigo Biolaboratories Category ELISA Kit

anti-PSMD10 antibody [1F4] - ARG57155 from Arigo Biolaboratories Category ELISA Kit

Human 26S proteasome non-ATPase regulatory subunit 10 (PSMD10) ELISA Kit - AE25419HU from ARP American Research Products Category ELISA Kit Prices $549.00 Sizes 96 t Sensitivity 0.059 ng/mL Range 0.156-10 ng/mL

Proteasome 26S Subunit, Non ATPase 10 (PSMD10), ELISA Kit - MBS451629 from MyBioSource Category ELISA Kit Prices $445.00, $590.00, $2,620.00, $5,095.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity <0.059ng/mL Range 0.156-10ng/mL

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