ZBP1

Gene Symbol ZBP1
Entrez Gene 81030
Alt Symbol C20orf183, DAI, DLM-1, DLM1
Species Human
Gene Type protein-coding
Description Z-DNA binding protein 1
Other Description DNA-dependent activator of IFN-regulatory factors|DNA-dependent activator of IRFs|DNA-dependent activator of interferon regulatory factors|Z-DNA-binding protein 1|tumor stroma and activated macrophage protein DLM-1
Swissprots Q5JY39 Q9H171 Q9BYW4 F5GYT1 B3KVA1 A2A2F7
Accessions EAW75509 EAW75510 EAW75511 EAW75512 EAW75513 Q9H171 AI659939 AI925506 AJ300575 CAC18810 AK122761 BAG53713 AK128405 AK290918 BAF83607 AK314062 AX775973 CAE11686 AX775975 CAE11687 BC028218 AAH28218 BC131706 AAI31707 BF511589 CT002036 DA674238 DA676308 DB331848 XM_011529057 XP_011527359 XM_011529058 XP_011527360 XM_011529059 XP_011527361 XR_936633 XR_936634 XR_936636 XR_936637 XR_936638 XR_936639 XR_936640 NM_001160417 NP_001153889 NM_001160418 NP_001153890 NM_001160419 NP_001153891 NM_030776 NP_110403
Function Participates in the detection by the host's innate immune system of DNA from viral, bacterial or even host origin. Plays a role in host defense against tumors and pathogens. Acts as a cytoplasmic DNA sensor which, when activated, induces the recruitment of TBK1 and IRF3 to its C-terminal region and activates the downstream interferon regulatory factor (IRF) and NF-kappa B transcription factors, leading to type-I interferon production. ZBP1-induced NF-kappaB activation probably involves the recruitment of the RHIM containing kinases RIPK1 and RIPK3 (By similarity). {ECO:0000250}.
Tissue Specificity Highly expressed in lymphatic tissues including lymph node, leukocytes, tonsil, bone marrow and spleen. Expressed to a lesser extent in thymus, lung and liver.
Top Pathways Cytosolic DNA-sensing pathway

Z-DNA binding protein 1, ZBP1, Human, ELISA Kit - CSB-E11795h from ARP American Research Products

Category ELISA Kit
Prices $495.00, $695.00, $696.00, $699.00
Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Z DNA binding protein, ELISA Kit - MBS732908 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,850.00, $5,340.00
Sizes 48 -strip-wells- (Competitive), 96 -strip-wells- (Competitive), 5x96-strip-wells- (Competitive), 10x96-strip-wells- (Competitive)
Sensitivity 0.1 ng/mL.

Z-Dna Binding Protein, ELISA Kit - MBS024832 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Z-Dna Binding Protein, ELISA Kit - MBS024586 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Z-Dna Binding Protein, ELISA Kit - MBS020752 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Z-DNA binding protein, ELISA Kit - MBS742936 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 1.0 pg/mL.

Z-Dna Binding Protein, ELISA Kit - MBS037402 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Z-Dna Binding Protein, ELISA Kit - MBS037156 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Z-Dna Binding Protein, ELISA Kit - MBS015142 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Z-Dna Binding Protein, ELISA Kit - MBS019245 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Z-Dna Binding Protein, ELISA Kit - MBS039992 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Z-Dna Binding Protein, ELISA Kit - MBS099644 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Z-Dna Binding Protein, ELISA Kit - MBS100669 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Z-Dna Binding Protein, ELISA Kit - MBS071232 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Z-Dna Binding Protein, ELISA Kit - MBS039744 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Z-DNA binding protein, ELISA Kit - MBS725570 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Z-Dna Binding Protein, ELISA Kit - MBS029006 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 5.0pg/ml.
Range 31.2pg/ml-1000pg/ml.

Z-Dna Binding Protein, ELISA Kit - MBS005967 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Z-Dna Binding Protein, ELISA Kit - MBS033103 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Z-DNA binding protein, ELISA Kit - MBS739671 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 1.0 pg/mL.

Z-DNA binding protein, ELISA Kit - MBS734814 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Z-DNA binding protein, ELISA Kit - MBS735345 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 1.0 pg/mL.

Z-Dna Binding Protein, ELISA Kit - MBS106354 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Z-DNA binding protein, ELISA Kit - MBS732283 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 0.1 nmol/L.

Z-Dna Binding Protein, ELISA Kit - MBS039039 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
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