RYK

Gene Symbol	RYK
Entrez Gene	6259
Alt Symbol	D3S3195, JTK5, JTK5A, RYK1
Species	Human
Gene Type	protein-coding
Description	receptor-like tyrosine kinase
Other Description	JTK5A protein tyrosine kinase|hydroxyaryl-protein kinase|tyrosine-protein kinase RYK
Swissprots	Q04696 P34925
Accessions	EAW79155 P34925 AB209405 BAD92642 BC021700 AAH21700 BC148614 AAI48615 BC153090 AAI53091 BQ003586 CN309980 S59184 AAB26341 X69970 CAA49591 X96588 CAA65406 XR_924160 NM_001005861 NP_001005861 NM_002958 NP_002949
Function	May be a coreceptor along with FZD8 of Wnt proteins, such as WNT1, WNT3, WNT3A and WNT5A. Involved in neuron differentiation, axon guidance, corpus callosum establishment and neurite outgrowth. In response to WNT3 stimulation, receptor C- terminal cleavage occurs in its transmembrane region and allows the C-terminal intracellular product to translocate from the cytoplasm to the nucleus where it plays a crucial role in neuronal development. {ECO:0000269|PubMed:15454084}.
Subcellular Location	Membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}. Note=In cells that have undergone neuronal differentiation, the C-terminal cleaved part is translocated from the cytoplasm to the nucleus. {ECO:0000250}.
Tissue Specificity	Observed in all the tissues examined.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

RYK (F35 P7 D7 F5) - sc-83082 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Mouse Clonality Monoclonal

RYK (C-17) - sc-83080 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

RYK (A-19) - sc-83079 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

RYK (H-190) - sc-83081 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

RYK (N-19) - sc-83078 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Anti-RYK antibody - ab5518 from Abcam Prices $359.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-RYK antibody - ab5513 from Abcam Prices $378.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-RYK antibody - ab173646 from Abcam Prices $376.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-RYK antibody - ab135670 from Abcam Prices $376.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-RYK antibody - ab172267 from Abcam Prices $376.00 Sizes 50 µg Host Mouse Clonality Polyclonal

Anti-RYK antibody [EPR5168(2)(B)] - ab128866 from Abcam Prices $379.00 Sizes 100 µl Host Rabbit Clonality Monoclonal Clone EPR5168(2)(B)

Anti-RYK antibody [EPR5169(2)] - ab124961 from Abcam Prices $385.00 Sizes 100 µl Host Rabbit Clonality Monoclonal Clone EPR5169(2)

Anti-RYK antibody [F30 P7 D7 F5] - ab33519 from Abcam Prices $370.00 Sizes 50 µg Host Mouse Clonality Monoclonal Clone F30 P7 D7 F5

Anti-RYK Antibody (aa160-190) - LS-C99131 from LifeSpan Bioscience Prices $295.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-RYK Antibody - LS-C75591 from LifeSpan Bioscience Prices $605.00 Sizes 100 µg Host Sheep Clonality Polyclonal

Anti-RYK Antibody (aa98-110) - LS-C155015 from LifeSpan Bioscience Prices $335.00 Sizes 100 µg Host Goat Clonality Polyclonal

Anti-RYK Antibody (clone 240CT2.2.4, AP) - LS-C250412 from LifeSpan Bioscience Prices $545.00 Sizes 100 µl Host Mouse Clonality Monoclonal Clone 240CT2.2.4

Anti-RYK Antibody (clone 240CT2.2.4, APC) - LS-C250413 from LifeSpan Bioscience Prices $545.00 Sizes 100 µl Host Mouse Clonality Monoclonal Clone 240CT2.2.4

Anti-RYK Antibody (clone 240CT2.2.4, Biotin) - LS-C250414 from LifeSpan Bioscience Prices $545.00 Sizes 100 µl Host Mouse Clonality Monoclonal Clone 240CT2.2.4

Anti-RYK Antibody (clone 240CT2.2.4, FITC) - LS-C250417 from LifeSpan Bioscience Prices $545.00 Sizes 100 µl Host Mouse Clonality Monoclonal Clone 240CT2.2.4

Anti-RYK Antibody (clone 240CT2.2.4, Azide-free, HRP) - LS-C250419 from LifeSpan Bioscience Prices $545.00 Sizes 100 µl Host Mouse Clonality Monoclonal Clone 240CT2.2.4

Anti-RYK Antibody (clone 240CT2.2.4, PE) - LS-C250418 from LifeSpan Bioscience Prices $545.00 Sizes 100 µl Host Mouse Clonality Monoclonal Clone 240CT2.2.4

Anti-RYK Antibody (aa168-198, AP) - LS-C268684 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-RYK Antibody (aa168-198, APC) - LS-C268686 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-RYK Antibody (aa196-413, clone 240CT2.2.4) - LS-C162823 from LifeSpan Bioscience Prices $295.00 Sizes 400 µl Host Mouse Clonality Monoclonal Clone 240CT2.2.4

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