RYK

Gene Symbol	RYK
Entrez Gene	6259
Alt Symbol	D3S3195, JTK5, JTK5A, RYK1
Species	Human
Gene Type	protein-coding
Description	receptor-like tyrosine kinase
Other Description	JTK5A protein tyrosine kinase|hydroxyaryl-protein kinase|tyrosine-protein kinase RYK
Swissprots	Q04696 P34925
Accessions	EAW79155 P34925 AB209405 BAD92642 BC021700 AAH21700 BC148614 AAI48615 BC153090 AAI53091 BQ003586 CN309980 S59184 AAB26341 X69970 CAA49591 X96588 CAA65406 XR_924160 NM_001005861 NP_001005861 NM_002958 NP_002949
Function	May be a coreceptor along with FZD8 of Wnt proteins, such as WNT1, WNT3, WNT3A and WNT5A. Involved in neuron differentiation, axon guidance, corpus callosum establishment and neurite outgrowth. In response to WNT3 stimulation, receptor C- terminal cleavage occurs in its transmembrane region and allows the C-terminal intracellular product to translocate from the cytoplasm to the nucleus where it plays a crucial role in neuronal development. {ECO:0000269|PubMed:15454084}.
Subcellular Location	Membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}. Note=In cells that have undergone neuronal differentiation, the C-terminal cleaved part is translocated from the cytoplasm to the nucleus. {ECO:0000250}.
Tissue Specificity	Observed in all the tissues examined.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human RYK protein fragment - ab139623 from Abcam Category Protein Source Baculovirus infected sf9 cells Species Human

Human RYK protein fragment - ab114531 from Abcam Category Protein Source Wheat germ Species Human

RYK Antibody Blocking Peptide - LS-E5401 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

RYK Antibody Blocking Peptide - LS-E9184 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

RYK Antibody Blocking Peptide - LS-E9183 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

RYK Antibody Blocking Peptide - LS-E9185 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

RYK Antibody Blocking Peptide - LS-E27902 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Ryk Protein - H00006259-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Ryk Peptide - P2718 from Novus Biologicals Category Peptide Species Human

RYK-Antibody-Center-C397-Blocking-Peptide - BP7677c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

RYK-Antibody-C-term-Blocking-Peptide - BP7677b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

RYK-Antibody-Blocking-Peptide - BP7677a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Recombinant Human Ryk Fc Chimera, CF - 4907-RK-050 from R&D Systems Category Protein Source Chinese Hamster Ovary cell line, CHO-derived

Ryk Peptide - AC21-2678-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

Tyrosine-protein kinase RYK - H00006259-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Tyrosine-protein kinase RYK - H00006259-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

RYK fusion protein - ag17540 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

RYK fusion protein - Ag17669 from Proteintech Group Category Protein Source E. coli -derived, PET28a Species Human

RYK Peptide - 350485 from ABBIOTEC Category Peptide Prices $50.00 Sizes 100 µg

Recombinant Human RYK - RYK-31340TH from Creative Biomart Category Protein Source Wheat germ

Recombinant Human RYK, GST-tagged - RYK-262H from Creative Biomart Category Protein Source Sf9 insect cells using baculovirus Species Human

Recombinant Human RYK, Fc Chimera - RYK-633H from Creative Biomart Category Protein Source CHO cells Species Human

Recombinant Related To Receptor Tyrosine Kinase (RYK) - RPM129Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Related To Receptor Tyrosine Kinase (RYK) - RPM129Mu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

RYK protein-GST fusion - 009-001-T25 from Rockland Immunochemicals Inc Category Protein Prices $499.00 Sizes 50 µg Species Human

Search more