RYK

Gene Symbol	RYK
Entrez Gene	6259
Alt Symbol	D3S3195, JTK5, JTK5A, RYK1
Species	Human
Gene Type	protein-coding
Description	receptor-like tyrosine kinase
Other Description	JTK5A protein tyrosine kinase|hydroxyaryl-protein kinase|tyrosine-protein kinase RYK
Swissprots	Q04696 P34925
Accessions	EAW79155 P34925 AB209405 BAD92642 BC021700 AAH21700 BC148614 AAI48615 BC153090 AAI53091 BQ003586 CN309980 S59184 AAB26341 X69970 CAA49591 X96588 CAA65406 XR_924160 NM_001005861 NP_001005861 NM_002958 NP_002949
Function	May be a coreceptor along with FZD8 of Wnt proteins, such as WNT1, WNT3, WNT3A and WNT5A. Involved in neuron differentiation, axon guidance, corpus callosum establishment and neurite outgrowth. In response to WNT3 stimulation, receptor C- terminal cleavage occurs in its transmembrane region and allows the C-terminal intracellular product to translocate from the cytoplasm to the nucleus where it plays a crucial role in neuronal development. {ECO:0000269|PubMed:15454084}.
Subcellular Location	Membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}. Note=In cells that have undergone neuronal differentiation, the C-terminal cleaved part is translocated from the cytoplasm to the nucleus. {ECO:0000250}.
Tissue Specificity	Observed in all the tissues examined.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Phosphotyrosine RYK ELISA Kit - RAB0991 from Sigma-Aldrich Category ELISA Kit Prices $637.00 Sizes 1 kt

Custom Human Ryk ELISA - ELH-RYK from RayBiotech Category ELISA Kit Prices $615.00, $1,107.00, $2,460.00 Sizes 1 plate kit, 2 plate kit, 5 plate kit

RYK receptor-like tyrosine kinase, ELISA Kit - MBS9340724 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Custom Human Ryk Elisa kit - orb305383 from Biorbyt Category ELISA Kit Prices $1,148.00, $1,981.00, $4,284.00 Sizes 96 assays, 192 assays, 480 assays

Human Ryk ELISA - RAB1672 from Sigma-Aldrich Prices $615.00 Sizes 1 kt

Custom Human Ryk ELISA - ELH-RYK-1 from RayBiotech Category ELISA Kit Prices $615.00, $1,107.00, $2,460.00 Sizes 1 plate kit, 2 plate kit, 5 plate kit

Custom Human Phosphotyrosine RYK ELISA - PEL-RYK-Y-1 from RayBiotech Category ELISA Kit Prices $615.00, $1,107.00, $2,460.00 Sizes 1 plate kit, 2 plate kit, 5 plate kit

Human RYK ELISA Kit - E034041 from Biobool Category ELISA Kit

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