IL11

Gene Symbol	IL11
Entrez Gene	3589
Alt Symbol	AGIF, IL-11
Species	Human
Gene Type	protein-coding
Description	interleukin 11
Other Description	adipogenesis inhibitory factor\|interleukin-11\|oprelvekin
Swissprots	Q96EB4 P20809 B4DQV5
Accessions	AAO13493 EAW72371 P20809 AK290572 BAF83261 AK298973 BAG61067 AK315294 BAG37700 BC012506 AAH12506 BF055151 M57765 AAA59132 X58377 CAA41266 NM_000641 NP_000632 NM_001267718 NP_001254647
Function	Cytokine that stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production (PubMed:2145578). Also promotes the proliferation of hepatocytes in response to liver damage. Binding to its receptor formed by IL6ST and either IL11RA1 or IL11RA2 activates a signaling cascade that promotes cell proliferation (PubMed:12919066). Signaling leads to the activation of intracellular protein kinases and the phosphorylation of STAT3. {ECO:0000250\|UniProtKB:P47873, ECO:0000269\|PubMed:12919066, ECO:0000269\|PubMed:2145578}.
Subcellular Location	Secreted {ECO:0000269\|PubMed:1828438, ECO:0000269\|PubMed:2145578}.
Top Pathways	Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Hematopoietic cell lineage, Rheumatoid arthritis

IL-11 (H-169) - sc-7924 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Rabbit
Clonality	Polyclonal

IL-11 (H-169): sc-7924. Western blot analysis of human recombinant IL-11.

IL-11 (D-20) - sc-1277 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

IL-11 (D-20): sc-1277. Western blot analysis of human recombinant IL-11.

IL-11 (F-3) - sc-133084 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Mouse
Clonality	Monoclonal

IL-11 (F-3): sc-133084. Western blot analysis of IL-11 expression in non-transfected 293T: sc-117752 (A), human IL-11 transfected 293T: sc-113495 (B), An3 CA (C) and NIH/3T3 (D) whole cell lysates.

IL-11 (A-9) - sc-133063 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Mouse
Clonality	Monoclonal

IL-11 (A-9): sc-133063. Western blot analysis of human recombinant IL-11.

IL-11 (A-7) - sc-133062 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Mouse
Clonality	Monoclonal

IL-11 (A-7): sc-133062. Western blot analysis of human recombinant IL-11.

Anti-IL11 antibody - ab76589 from Abcam

Prices	$370.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-IL11 antibody (ab76589) at 1 µg/ml + Human Plasma Total Protein Lysate at 10 µgSecondaryGoat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-IL11 antibody - ab109813 from Abcam

Prices	$370.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

Anti-IL11 antibody - ab36626 from Abcam

Prices	$406.00
Sizes	50 µg
Host	Chicken
Clonality	Polyclonal

ELISA: recombinant Interleukin 11 protein was used as test antigen (5µg/ml). Anti-IL-11 IgY antibody (ab36626) was used as primary antibody and Rabbit anti-IgY-HRP was used as secondary antibody.

Anti-IL11 antibody - ab10780 from Abcam

Prices	$370.00
Sizes	200 µg
Host	Goat
Clonality	Polyclonal

Anti-IL11 antibody [6D9A1] - ab130083 from Abcam

Prices	$370.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	6D9A1

Anti-IL11 antibody [6D9A1] (ab130083) at 1/500 dilution + truncated Human IL11 recombinant protein

Anti-IL11 antibody (Biotin) - ab83120 from Abcam

Prices	$370.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

Anti-IL11 antibody [EPR15253] - ab187167 from Abcam

Prices	$357.00
Sizes	100 µl
Host	Rabbit
Clonality	Monoclonal
Clone	EPR15253

Anti-IL11 antibody [EPR15253] (ab187167) at 1/1000 dilution + Rat plasma lysate at 10 µgSecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution

Anti-IL11 antibody [KT62] (HRP) - ab106492 from Abcam

Prices	$370.00
Sizes	100 µl
Host	Mouse
Clonality	Monoclonal
Clone	KT62

ab106492 at 1/1000 dilution detecting IL11 by sandwich ELISA. The capture antibody is an mouse monoclonal (IgG1) raised against Human IL11.

Anti-IL11 antibody [MM0361-9T27] - ab89887 from Abcam

Prices	$370.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	MM0361-9T27

Anti-IL11 antibody [P107] - ab26042 from Abcam

Prices	$370.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	P107

Anti-IL11 Antibody - LS-C104366 from LifeSpan Bioscience

Prices	$285.00, $325.00
Sizes	50 µg, 100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-IL11 Antibody - LS-C104441 from LifeSpan Bioscience

Prices	$255.00
Sizes	500 µg
Host	Mouse
Clonality	Monoclonal

Anti-IL11 Antibody - LS-C130249 from LifeSpan Bioscience

Prices	$405.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal

Anti-IL11 Antibody - LS-C86939 from LifeSpan Bioscience

Prices	$345.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

Anti-IL11 Antibody - LS-C37018 from LifeSpan Bioscience

Prices	$495.00
Sizes	500 µg
Host	Mouse
Clonality	Monoclonal

Anti-IL11 Antibody (clone GF1) - LS-C190297 from LifeSpan Bioscience

Prices	$365.00
Sizes	100 µl
Host	Mouse
Clonality	Monoclonal
Clone	GF1

Anti-IL11 Antibody (clone KT62, HRP) - LS-C193875 from LifeSpan Bioscience

Prices	$445.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	KT62

Anti-IL11 Antibody (clone 3C6) - LS-C197521 from LifeSpan Bioscience

Prices	$355.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	3C6

Anti-IL11 Antibody (aa27-76) - LS-C199899 from LifeSpan Bioscience

Prices	$315.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-IL11 Antibody (clone 6D9A1) - LS-C171354 from LifeSpan Bioscience

Prices	$275.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	6D9A1

Western blot of IL11 mouse mAb against truncated IL- 11 recombinant protein.

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