IL11

Gene Symbol	IL11
Entrez Gene	3589
Alt Symbol	AGIF, IL-11
Species	Human
Gene Type	protein-coding
Description	interleukin 11
Other Description	adipogenesis inhibitory factor|interleukin-11|oprelvekin
Swissprots	Q96EB4 P20809 B4DQV5
Accessions	AAO13493 EAW72371 P20809 AK290572 BAF83261 AK298973 BAG61067 AK315294 BAG37700 BC012506 AAH12506 BF055151 M57765 AAA59132 X58377 CAA41266 NM_000641 NP_000632 NM_001267718 NP_001254647
Function	Cytokine that stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production (PubMed:2145578). Also promotes the proliferation of hepatocytes in response to liver damage. Binding to its receptor formed by IL6ST and either IL11RA1 or IL11RA2 activates a signaling cascade that promotes cell proliferation (PubMed:12919066). Signaling leads to the activation of intracellular protein kinases and the phosphorylation of STAT3. {ECO:0000250|UniProtKB:P47873, ECO:0000269|PubMed:12919066, ECO:0000269|PubMed:2145578}.
Subcellular Location	Secreted {ECO:0000269|PubMed:1828438, ECO:0000269|PubMed:2145578}.
Top Pathways	Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Hematopoietic cell lineage, Rheumatoid arthritis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

IL-11 (Interleukin-11) Human ELISA Kit - ab100551 from Abcam Category ELISA Kit Prices $489.00 Sizes 1 x 96 tests Sensitivity < 3 pg/ml Range 3.29 pg/ml - 800 pg/ml

IL-11 (Interleukin-11) Human SimpleStep ELISA™ Kit - ab189569 from Abcam Category ELISA Kit Prices $484.00 Sizes 1 x 96 tests Sensitivity 12 pg/ml Range 43 pg/ml - 6000 pg/ml

Human IL11 ELISA Kit (Sandwich ELISA) - LS-F2483 from LifeSpan Bioscience Category ELISA Kit Prices $490.00 Sizes 1 plate Sensitivity 10 pg/ml Range 1.097-266.7 pg/ml

Human IL11 ELISA Kit (Sandwich ELISA) - LS-F5082 from LifeSpan Bioscience Category ELISA Kit Prices $650.00 Sizes 1 plate Sensitivity 5.7 pg/ml Range 1.097-266.7 pg/ml

Mouse IL11 ELISA Kit (Sandwich ELISA) - LS-F5083 from LifeSpan Bioscience Category ELISA Kit Prices $670.00 Sizes 1 plate Sensitivity 2.8 pg/ml Range 1.097-266.7 pg/ml

Rat IL11 ELISA Kit (Sandwich ELISA) - LS-F5481 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity 5.9 pg/ml Range 1.097-266.7 pg/ml

Human IL11 ELISA Kit (Sandwich ELISA) - LS-F110 from LifeSpan Bioscience Category ELISA Kit Prices $460.00, $840.00, $1,960.00 Sizes 1 plate, 2 plate, 5 plate Sensitivity 1.097 pg/ml Range 1.097-266.7 pg/ml

Mouse IL11 ELISA Kit (Sandwich ELISA) - LS-F254 from LifeSpan Bioscience Category ELISA Kit Prices $460.00, $840.00, $1,960.00 Sizes 1 plate, 2 plate, 5 plate Sensitivity 0.617 ng/ml Range 1.097-266.7 pg/ml

Human IL11 ELISA Kit (Sandwich ELISA) - LS-F637 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate Range 1.097-266.7 pg/ml

Mouse IL11 ELISA Kit (Sandwich ELISA) - LS-F11737 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 15.6 Range 1.097-266.7 pg/ml

Human IL11 ELISA Kit (Sandwich ELISA) - LS-F11736 from LifeSpan Bioscience Category ELISA Kit Prices $530.00 Sizes 1 plate Sensitivity 15.6 Range 1.097-266.7 pg/ml

Human IL-11 ELISA Kit - RAB0250 from Sigma-Aldrich Category ELISA Kit Prices $423.50 Sizes 1 kt

Human IL-11 Quantikine ELISA Kit - D1100 from R&D Systems Category ELISA Kit Prices $479.00 Sizes 1 kit Sensitivity 8 pg/mL Range 15.6 - 1,000 pg/mL (Cell Culture Supernates), 31.2 - 2,000 pg/mL (Serum, EDTA Plasma, Heparin Plasma, Citrate Plasma)

Human IL-11 DuoSet ELISA - DY218 from R&D Systems Category ELISA Kit Prices $649.00 Sizes 1 kit (for 15 Plates) Range 31.20 - 2,000 pg/mL

Mouse IL-11 DuoSet ELISA - DY418 from R&D Systems Category ELISA Kit Prices $649.00 Sizes 1 kit (for 15 Plates) Range 125.00 - 8,000 pg/mL

Human IL11 ELISA kit - 55R-2123 from Fitzgerald Category ELISA Kit Prices $545.00 Sizes 96 tests

Mouse IL11 ELISA kit - 55R-2203 from Fitzgerald Category ELISA Kit Prices $545.00 Sizes 96 tests

IL-11 ELISA Kit (Human) : 96 Wells (OKAG00130) - OKAG00130 from Aviva Systems Biology Category ELISA Kit Prices $390.00 Sizes 96 wells Sensitivity 32 pg/mL Range 32-2,000 pg/mL

Human IL-11 ELISA Kit - abx056203 from Abbexa Category ELISA Kit

Human Interleukin 11 ELISA Kit - abx152013 from Abbexa Category ELISA Kit Sensitivity 5.8 pg/ml Range 15.625 pg/ml - 1000 pg/ml

Human Interleukin 11 ELISA Kit - abx052232 from Abbexa Category ELISA Kit

Interleukin 11, IL-11, Human, ELISA Kit - E-EL-H5022 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 18.75 Range 31.25-2000pg/mL

Interleukin 11 (IL11), Human, ELISA Kit - SEA057Hu from ARP American Research Products Category ELISA Kit Prices $650.00 Sizes 96 t Sensitivity 5.8pg/mL Range 15.6-1,000pg/mL

Interleukin 11, Human, ELISA Kit - E01I0352 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t Sensitivity 1.0pg/ml Range 50-1000pg/ml

Interleukin 11, IL-11, Human, ELISA Kit - CSB-E04596h from ARP American Research Products Category ELISA Kit Prices $365.00, $495.00, $496.00, $498.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 7.81 pg/ml Range 31.25 pg/ml-2000 pg/ml

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