FANCL

Gene Symbol FANCL
Entrez Gene 55120
Alt Symbol FAAP43, PHF9, POG
Species Human
Gene Type protein-coding
Description Fanconi anemia, complementation group L
Other Description E3 ubiquitin-protein ligase FANCL|PHD finger protein 9|fanconi anemia group L protein|fanconi anemia-associated polypeptide of 43 kDa
Swissprots Q6GU60 Q9NW38
Accessions AAY15020 EAX00056 EAX00057 EAX00058 EAX00059 EAX00060 EAX00061 Q9NW38 AK001197 BAA91548 AK225147 AK297736 BAG60086 AK309671 AL036481 BC009042 AAH09042 BC037570 BC041627 BC054517 AAH54517 BQ574618 DB032206 XM_005264395 XP_005264452 XM_005264397 XP_005264454 XM_011532939 XP_011531241 XM_011532940 XP_011531242 XM_011532941 XP_011531243 XM_011532942 XP_011531244 XM_011532943 XP_011531245 XM_011532944 XP_011531246 XM_011532945 XP_011531247 XR_939692 NM_001114636 NP_001108108 NM_018062 NP_060532
Function Ubiquitin ligase protein that mediates monoubiquitination of FANCD2, a key step in the DNA damage pathway. Also mediates monoubiquitination of FANCI. May stimulate the ubiquitin release from UBE2W. May be required for proper primordial germ cell proliferation in the embryonic stage, whereas it is probably not needed for spermatogonial proliferation after birth. {ECO:0000269|PubMed:12973351, ECO:0000269|PubMed:16916645, ECO:0000269|PubMed:17938197, ECO:0000269|PubMed:19111657, ECO:0000269|PubMed:19589784}.
Subcellular Location Cytoplasm. Nucleus.
Top Pathways Ubiquitin mediated proteolysis, Fanconi anemia pathway

FANCL (B-11) - sc-137067 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
FANCL (B-11): sc-137067. Western blot analysis of FANCL expression in non-transfected: sc-117752 (A) and human FANCL transfected: sc-116313 (B) 293T whole cell lysates.

FANCL (C-4) - sc-137076 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
FANCL (C-4): sc-137076. Western blot analysis of FANCL expression in non-transfected: sc-117752 (A) and human FANCL transfected: sc-117142 (B) 293T whole cell lysates.

FANCL (H-197) - sc-66887 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
FANCL (H-197): sc-66887. Western blot analysis of FANCL expression in non-transfected 293T: sc-117752 (A), human FANCL transfected 293T: sc-117142 (B) and Hep G2 (C) whole cell lysates.

FANCL (K-12) - sc-46114 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

FANCL (H-8) - sc-137068 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
FANCL (H-8): sc-137068. Western blot analysis of FANCL expression in non-transfected: sc-117752 (A) and human FANCL transfected: sc-117142 (B) 293T whole cell lysates.

FANCL (N-13) - sc-46116 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
FANCL (N-13): sc-46116. Immunoperoxidase staining of formalin fixed, paraffin-embedded human gall bladder tissue showing cytoplasmic and membrane staining of glandular cells.

Anti-FANCL antibody - ab94458 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human pineal tissue labelling FANCL with ab94458 at 1/100. A Cy3-conjugated donkey anti-rabbit IgG (1/200) was used as the secondary antibody. Positive staining shown in the cytoplasm and nuclei of pinealocytes. Magnification: 20X. Exposure time: 0.5 - 2.0 seconds. Left - DAPI. Middle - FANCL. Right - Merge.

Anti-FANCL antibody - ab169690 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-FANCL antibody (ab169690) at 1 µg/mlLane 1 : FANCL transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 15 µl per lane.

Anti-FANCL antibody - C-terminal - ab174210 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-FANCL antibody - C-terminal (ab174210) at 1/100 dilution + 293 cell line lysate at 35 µg

Anti-PHF9 / FANCL Antibody (Internal) - LS-C210087 from LifeSpan Bioscience

Prices $295.00
Sizes 250 µl
Host Rabbit
Clonality Polyclonal

Anti-PHF9 / FANCL Antibody (N-Terminus) - LS-C210090 from LifeSpan Bioscience

Prices $295.00
Sizes 250 µl
Host Rabbit
Clonality Polyclonal

Anti-PHF9 / FANCL Antibody (aa274-302, PE) - LS-C222495 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PHF9 / FANCL Antibody (aa274-302, AP) - LS-C226756 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PHF9 / FANCL Antibody (aa274-302, APC) - LS-C226760 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PHF9 / FANCL Antibody (aa274-302, Biotin) - LS-C226761 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PHF9 / FANCL Antibody (aa274-302, Azide-free, HRP) - LS-C226763 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PHF9 / FANCL Antibody - LS-C307476 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-PHF9 / FANCL Antibody (aa274-302, FITC) - LS-C226762 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PHF9 / FANCL Antibody - LS-C310317 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PHF9 / FANCL Antibody - LS-C311135 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-PHF9 / FANCL Antibody (aa143-192) - LS-C111878 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
FANCL antibody LS-C111878 Western blot of Fetal Heart lysate.

Anti-PHF9 / FANCL Antibody (aa274-302) - LS-C321289 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PHF9 / FANCL Antibody (aa274-302) - LS-C157744 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
FANCL Antibody western blot of 293 cell line lysates (35 ug/lane). The FANCL antibody detected the FANCL protein (arrow).

Anti-PHF9 / FANCL Antibody (aa287-298) - LS-C139594 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
FANCL antibody (1 ug/ml) staining of Human Bone Marrow lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

FANCL Antibody - NBP1-84758 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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