FANCL

Gene Symbol	FANCL
Entrez Gene	55120
Alt Symbol	FAAP43, PHF9, POG
Species	Human
Gene Type	protein-coding
Description	Fanconi anemia, complementation group L
Other Description	E3 ubiquitin-protein ligase FANCL|PHD finger protein 9|fanconi anemia group L protein|fanconi anemia-associated polypeptide of 43 kDa
Swissprots	Q6GU60 Q9NW38
Accessions	AAY15020 EAX00056 EAX00057 EAX00058 EAX00059 EAX00060 EAX00061 Q9NW38 AK001197 BAA91548 AK225147 AK297736 BAG60086 AK309671 AL036481 BC009042 AAH09042 BC037570 BC041627 BC054517 AAH54517 BQ574618 DB032206 XM_005264395 XP_005264452 XM_005264397 XP_005264454 XM_011532939 XP_011531241 XM_011532940 XP_011531242 XM_011532941 XP_011531243 XM_011532942 XP_011531244 XM_011532943 XP_011531245 XM_011532944 XP_011531246 XM_011532945 XP_011531247 XR_939692 NM_001114636 NP_001108108 NM_018062 NP_060532
Function	Ubiquitin ligase protein that mediates monoubiquitination of FANCD2, a key step in the DNA damage pathway. Also mediates monoubiquitination of FANCI. May stimulate the ubiquitin release from UBE2W. May be required for proper primordial germ cell proliferation in the embryonic stage, whereas it is probably not needed for spermatogonial proliferation after birth. {ECO:0000269|PubMed:12973351, ECO:0000269|PubMed:16916645, ECO:0000269|PubMed:17938197, ECO:0000269|PubMed:19111657, ECO:0000269|PubMed:19589784}.
Subcellular Location	Cytoplasm. Nucleus.
Top Pathways	Ubiquitin mediated proteolysis, Fanconi anemia pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

FANCL (Human) IP-WB Antibody Pair - H00055120-PW1 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

Fanconi anemia, complementation group L, ELISA Kit - MBS9338607 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human FANCL ELISA Kit - E014424 from Biobool Category ELISA Kit

anti-FANCL antibody - ARG65320 from Arigo Biolaboratories Category ELISA Kit

E3 Ubiquitin-Protein Ligase FANCL (FANCL), ELISA Kit - MBS9907551 from MyBioSource Category ELISA Kit

E3 Ubiquitin-Protein Ligase FANCL (FANCL), ELISA Kit - MBS9907559 from MyBioSource Category ELISA Kit

E3 Ubiquitin-Protein Ligase FANCL (FANCL), ELISA Kit - MBS9907544 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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