FANCL

Gene Symbol	FANCL
Entrez Gene	55120
Alt Symbol	FAAP43, PHF9, POG
Species	Human
Gene Type	protein-coding
Description	Fanconi anemia, complementation group L
Other Description	E3 ubiquitin-protein ligase FANCL|PHD finger protein 9|fanconi anemia group L protein|fanconi anemia-associated polypeptide of 43 kDa
Swissprots	Q6GU60 Q9NW38
Accessions	AAY15020 EAX00056 EAX00057 EAX00058 EAX00059 EAX00060 EAX00061 Q9NW38 AK001197 BAA91548 AK225147 AK297736 BAG60086 AK309671 AL036481 BC009042 AAH09042 BC037570 BC041627 BC054517 AAH54517 BQ574618 DB032206 XM_005264395 XP_005264452 XM_005264397 XP_005264454 XM_011532939 XP_011531241 XM_011532940 XP_011531242 XM_011532941 XP_011531243 XM_011532942 XP_011531244 XM_011532943 XP_011531245 XM_011532944 XP_011531246 XM_011532945 XP_011531247 XR_939692 NM_001114636 NP_001108108 NM_018062 NP_060532
Function	Ubiquitin ligase protein that mediates monoubiquitination of FANCD2, a key step in the DNA damage pathway. Also mediates monoubiquitination of FANCI. May stimulate the ubiquitin release from UBE2W. May be required for proper primordial germ cell proliferation in the embryonic stage, whereas it is probably not needed for spermatogonial proliferation after birth. {ECO:0000269|PubMed:12973351, ECO:0000269|PubMed:16916645, ECO:0000269|PubMed:17938197, ECO:0000269|PubMed:19111657, ECO:0000269|PubMed:19589784}.
Subcellular Location	Cytoplasm. Nucleus.
Top Pathways	Ubiquitin mediated proteolysis, Fanconi anemia pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human FANCL full length protein - ab162967 from Abcam Category Protein Source Wheat germ Species Human

PHF9 / FANCL Antibody Blocking Peptide - LS-E6684 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PHF9 / FANCL Antibody Blocking Peptide - LS-E20424 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PHF9 / FANCL Antibody Blocking Peptide - LS-E27401 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

FANCL Recombinant Protein - H00055120-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

FANCL-AntibodyC-term-Blocking-peptide - BP19508b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

FANCL blocking peptide - GTX88033-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Rat, Bovine

FANCL Immunizing peptide - orb59819 from Biorbyt Category Peptide Prices $247.00 Sizes 100 μg Species Human, Mouse, Rat

FANCL Blocking Peptide - 33R-1506 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

FANCL Peptide - AC21-2225-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

FANCL - H00055120-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

FANCL - H00055120-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

FANCL Peptide - 42-798P from ProSci Category Peptide Species Human

FANCL fusion protein - Ag6192 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

FANCL fusion protein - ag6031 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

FANCL Peptide - 350524 from ABBIOTEC Category Peptide Prices $50.00 Sizes 100 µg

Recombinant Human FANCL, His-tagged - FANCL-12741H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human FANCL, GST-tagged - FANCL-191H from Creative Biomart Category Protein Source Sf9 insect cells using baculovirus Species Human

FANCL protein-GST fusion - 009-001-R93 from Rockland Immunochemicals Inc Category Protein Prices $499.00 Sizes 50 µg Species Human

FANCL protein-GST fusion - 009-001-R93S from Rockland Immunochemicals Inc Category Protein Prices $265.00 Sizes 20 µg Species Human

Recombinant Human E3 ubiquitin-protein ligase FANCL(FANCL) - CSB-YP882120HU CSB-EP882120HU CSB-BP882120HU CSB-MP882120HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

FANCL Protein - abx164918 from Abbexa Category Protein Species Human, Mouse, Rat

FANCL, Peptide - MBS427286 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse, Rat, Dog, Bovine

FANCL Recombinant Protein Antigen - NBP1-84759PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

FANCL Recombinant Protein Antigen - NBP1-84758PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

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