FANCL

Gene Symbol	FANCL
Entrez Gene	55120
Alt Symbol	FAAP43, PHF9, POG
Species	Human
Gene Type	protein-coding
Description	Fanconi anemia, complementation group L
Other Description	E3 ubiquitin-protein ligase FANCL|PHD finger protein 9|fanconi anemia group L protein|fanconi anemia-associated polypeptide of 43 kDa
Swissprots	Q6GU60 Q9NW38
Accessions	AAY15020 EAX00056 EAX00057 EAX00058 EAX00059 EAX00060 EAX00061 Q9NW38 AK001197 BAA91548 AK225147 AK297736 BAG60086 AK309671 AL036481 BC009042 AAH09042 BC037570 BC041627 BC054517 AAH54517 BQ574618 DB032206 XM_005264395 XP_005264452 XM_005264397 XP_005264454 XM_011532939 XP_011531241 XM_011532940 XP_011531242 XM_011532941 XP_011531243 XM_011532942 XP_011531244 XM_011532943 XP_011531245 XM_011532944 XP_011531246 XM_011532945 XP_011531247 XR_939692 NM_001114636 NP_001108108 NM_018062 NP_060532
Function	Ubiquitin ligase protein that mediates monoubiquitination of FANCD2, a key step in the DNA damage pathway. Also mediates monoubiquitination of FANCI. May stimulate the ubiquitin release from UBE2W. May be required for proper primordial germ cell proliferation in the embryonic stage, whereas it is probably not needed for spermatogonial proliferation after birth. {ECO:0000269|PubMed:12973351, ECO:0000269|PubMed:16916645, ECO:0000269|PubMed:17938197, ECO:0000269|PubMed:19111657, ECO:0000269|PubMed:19589784}.
Subcellular Location	Cytoplasm. Nucleus.
Top Pathways	Ubiquitin mediated proteolysis, Fanconi anemia pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human-FANCL-cDNA-Clone - DC08018 from Abgent, a WuXi AppTec company Prices $506.25 Sizes 10 µg Species Human Accession BC054517

FANCL - MBS1266483 from MyBioSource Species Human Accession BC054517

Human FANCL cDNA clone(NM_001114636.1) - CDFH006601 from Creative Biomart Species Human Accession NM_001114636.1

Human FANCL ORF Clone(NM_001114636.1) - CDCR348115 from Creative Biomart Species Human Accession NM_001114636.1

Human FANCL ORF Clone(NM_001114636.1) - CDCR348116 from Creative Biomart Species Human Accession NM_001114636.1

Human FANCL ORF Clone(NM_018062.3) - CDCL163127 from Creative Biomart Species Human Accession NM_018062.3

Human FANCL ORF clone(NM_018062.3) - CDCL184179 from Creative Biomart Species Human Accession NM_018062.3

Human FANCL Gene ORF cDNA clone in cloning vector - HG10520-M from Sino Biological Species Human

Human FANCL Gene ORF cDNA clone expression plasmid - HG10520-UT from Sino Biological Species Human

Human FANCL Gene ORF cDNA clone expression plasmid, N-His tag - HG10520-NH from Sino Biological Species Human

Human FANCL Gene ORF cDNA clone expression plasmid, N-Flag tag - HG10520-NF from Sino Biological Species Human

Human FANCL Gene ORF cDNA clone expression plasmid, N-Myc tag - HG10520-NM from Sino Biological Species Human

Human FANCL Gene ORF cDNA clone expression plasmid, C-HA tag - HG10520-CY from Sino Biological Species Human

Human FANCL Gene ORF cDNA clone expression plasmid, C-Flag tag - HG10520-CF from Sino Biological Species Human

Human FANCL Gene cDNA Clone (full-length ORF Clone), expression ready, N-HA-tagged - HG10520-NY from Sino Biological Species Human Accession NM_018062.3

Human FANCL Gene ORF cDNA clone expression plasmid, C-Myc tag - HG10520-CM from Sino Biological Species Human

Human FANCL Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG10520-ANG from Sino Biological Species Human

Human FANCL Gene ORF cDNA clone expression plasmid, C-Flag tag - HG10520-M-F from Sino Biological Species Human

Human FANCL Gene ORF cDNA clone expression plasmid, C-His tag - HG10520-CH from Sino Biological Species Human

Human FANCL Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG10520-ACR from Sino Biological Species Human

Human FANCL Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG10520-ANR from Sino Biological Species Human

Human FANCL ORF clone(NM_018062.3) - CDCL184179 from Creative biogene Species Human

Human FANCL ORF clone (NM_001114636.1) - CDCR063806 from Creative biogene Species Human

Human FANCL ORF Clone (BC054517) - CDCS407684 from Creative biogene Species Human Accession Q9NW38

Human FANCL cDNA Clone(NM_001114636.1) - CDFH006601 from Creative biogene Species Human

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