CD33

Gene Symbol	CD33
Entrez Gene	945
Alt Symbol	SIGLEC-3, SIGLEC3, p67
Species	Human
Gene Type	protein-coding
Description	CD33 molecule
Other Description	CD33 antigen (gp67)|gp67|myeloid cell surface antigen CD33|sialic acid binding Ig-like lectin 3|sialic acid-binding Ig-like lectin 3
Swissprots	F8WAL2 C9JEN7 Q8TD24 B4E3P8 P20138
Accessions	AAK83654 CAD36509 CCF76941 CCF76942 CDM22283 EAW71994 EAW71995 EAW71996 P20138 AK090470 BAC03451 AK293934 BAG57312 AK304810 BAG65560 AK309558 AW007749 AY162464 AAO26206 BC028152 AAH28152 BP295158 BP303860 CA426969 CA748646 DQ891726 ABM82652 DQ894903 ABM85829 M23197 AAA51948 XM_011527531 XP_011525833 XM_011527532 XP_011525834 XR_935875 NM_001082618 NP_001076087 NM_001177608 NP_001171079 NM_001772 NP_001763
Function	Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia (in vitro). {ECO:0000269|PubMed:10556798, ECO:0000269|PubMed:11320212}.
Subcellular Location	Cell membrane; Single-pass type I membrane protein.
Tissue Specificity	Monocytic/myeloid lineage cells.
Top Pathways	Hematopoietic cell lineage

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Mouse CD33 ELISA Kit (Sandwich ELISA) - LS-F9886 from LifeSpan Bioscience Category ELISA Kit Prices $670.00 Sizes 1 plate Sensitivity 0.156 ng/ml Range 0.156-10 ng/ml

Myeloid cell surface antigen CD33 (CD33), Human, ELISA Kit - CSB-EL004925HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 31.25 pg/ml Range 125 pg/ml-8000 pg/ml

Sialic Acid Binding Ig Like Lectin 3, SIGLEC3, Human, ELISA Kit - E-EL-H2026 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 0.094 Range 0.156-10ng/mL

Sialic Acid Binding Ig Like Lectin 3, SIGLEC3, Mouse, ELISA Kit - E-EL-M1052 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 0.094 Range 0.156-10ng/mL

Sialic Acid Binding Ig Like Lectin 3, SIGLEC3, Rabbit, ELISA Kit - E-EL-RB0870 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Sialic Acid Binding Ig Like Lectin 3, SIGLEC3, Chicken, ELISA Kit - E-EL-Ch0470 from ARP American Research Products Category ELISA Kit Prices $504.00 Sizes 96 t

Sialic Acid Binding Ig Like Lectin 3, SIGLEC3, Porcine, ELISA Kit - E-EL-P1170 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Sialic Acid Binding Ig Like Lectin 3, SIGLEC3, Guinea Pig, ELISA Kit - E-EL-GP0065 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t

Sialic Acid Binding Ig Like Lectin 3, SIGLEC3, Monkey, ELISA Kit - E-EL-MK0713 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 0.094 Range 0.156-10ng/mL

Human SIGLEC3 ELISA Kit - HS0116 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Anserine SIGLEC3 ELISA Kit - AS0116 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

ELISA Kit for Sialic Acid Binding Ig Like Lectin 3 (SIGLEC3) - SEA020Mu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.053ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA’s were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

Human SIGLEC3(Sialic Acid Binding Ig Like Lectin 3) ELISA Kit - E-EL-H2026 from Elabscience Category ELISA Kit Sensitivity 0.10 ng/mL Range 0.16—10 ng/mL

Human SIGLEC3 (Sialic Acid Binding Ig Like Lectin 3) CLIA Kit - E-CL-H1227 from Elabscience Category CLIA Kit Sensitivity 18.75 pg/mL Range Average Recovery (%)

CD33 molecule, ELISA Kit - MBS934912 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 31.25 pg/ml. Range 125 pg/ml-8000 pg/ml.

SIGLEC3, ELISA Kit - MBS2502194 from MyBioSource Category ELISA Kit Prices $410.00, $490.00, $2,040.00, $3,590.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.094ng/mL Range 0.156-10ng/mL

Human Myeloid cell surface antigen CD33(CD33) ELISA kit - CSB-EL004925HU from Cusabio Category ELISA Kit Sensitivity 31.25pg/ml Range 125 pg/ml-8000 pg/ml

Human Sialic Acid Binding Ig Like Lectin 3 ELISA - E01S0109 from BlueGene Biotech Category ELISA Kit Sensitivity 0.1 ng/ml

Human SIGLEC3(Sialic Acid Binding Ig Like Lectin 3) ELISA Kit - E-EL-H2027 from Iwai North America Inc. Category ELISA Kit Prices $580.00 Sizes 1 kit Sensitivity 37.5 pg/mLpg/mL Range 62.5~4000 pg/mL

Human SIGLEC12(Sialic Acid Binding Ig Like Lectin 12) ELISA Kit - E-EL-H2026 from Iwai North America Inc. Category ELISA Kit Prices $580.00 Sizes 1 kit Sensitivity 0.1 ng/mLng/mL Range 0.16~10 ng/mL

Human HJV/HFE2 (Hemojuvelin/Hemochromatosis Type 2) CLIA Kit - E-CL-H1147 from Iwai North America Inc. Category CLIA Kit Prices $722.50 Sizes 1 kit Sensitivity 0.094ng/mL Range 0.156-10ng/mL

Human SIGLEC3 (Sialic Acid Binding Ig Like Lectin 3) CLIA Kit - E-CL-H1227 from Iwai North America Inc. Category CLIA Kit Prices $722.50 Sizes 1 kit Sensitivity 0.094ng/mL Range 0.156-10ng/mL

Human CD33 ELISA Kit (Sandwich ELISA) - LS-F21205 from LifeSpan Bioscience Category ELISA Kit Prices $590.00 Sizes 1 plate Sensitivity 0.16 ng/ml Range 0.156-10 ng/ml

Mouse CD33 ELISA Kit (Sandwich ELISA) - LS-F21448 from LifeSpan Bioscience Category ELISA Kit Prices $590.00 Sizes 1 plate Sensitivity 0.16 ng/ml Range 0.156-10 ng/ml

SIGLEC3 (Sialic Acid Binding Ig Like Lectin 3), CLIA Kit - MBS2532653 from MyBioSource Category CLIA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 18.75pg/mL Range 31.25-2000pg/mL

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