CD33

Gene Symbol	CD33
Entrez Gene	945
Alt Symbol	SIGLEC-3, SIGLEC3, p67
Species	Human
Gene Type	protein-coding
Description	CD33 molecule
Other Description	CD33 antigen (gp67)|gp67|myeloid cell surface antigen CD33|sialic acid binding Ig-like lectin 3|sialic acid-binding Ig-like lectin 3
Swissprots	F8WAL2 C9JEN7 Q8TD24 B4E3P8 P20138
Accessions	AAK83654 CAD36509 CCF76941 CCF76942 CDM22283 EAW71994 EAW71995 EAW71996 P20138 AK090470 BAC03451 AK293934 BAG57312 AK304810 BAG65560 AK309558 AW007749 AY162464 AAO26206 BC028152 AAH28152 BP295158 BP303860 CA426969 CA748646 DQ891726 ABM82652 DQ894903 ABM85829 M23197 AAA51948 XM_011527531 XP_011525833 XM_011527532 XP_011525834 XR_935875 NM_001082618 NP_001076087 NM_001177608 NP_001171079 NM_001772 NP_001763
Function	Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia (in vitro). {ECO:0000269|PubMed:10556798, ECO:0000269|PubMed:11320212}.
Subcellular Location	Cell membrane; Single-pass type I membrane protein.
Tissue Specificity	Monocytic/myeloid lineage cells.
Top Pathways	Hematopoietic cell lineage

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human-CD33-cDNA-Clone - DC05785 from Abgent, a WuXi AppTec company Prices $491.40 Sizes 10 µg Species Human Accession BC028152

CD33 - MBS1265938 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC028152

Human CD33/Siglec-3 Gene ORF cDNA clone in cloning vector - HG12238-G from Sino Biological Species Human

Human CD33/Siglec-3 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG12238-ACG from Sino Biological Species Human

Human CD33/Siglec-3 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG12238-NF from Sino Biological Species Human

Human CD33/Siglec-3 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG12238-NM from Sino Biological Species Human

Human CD33/Siglec-3 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG12238-CF from Sino Biological Species Human

Human CD33/Siglec-3 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG12238-CM from Sino Biological Species Human

Human CD33/Siglec-3 Gene ORF cDNA clone expression plasmid, C-HA tag - HG12238-CY from Sino Biological Species Human

Human CD33/Siglec-3 Gene ORF cDNA clone expression plasmid, N-HA tag - HG12238-NY from Sino Biological Species Human

Human CD33/Siglec-3 Gene ORF cDNA clone expression plasmid, N-His tag - HG12238-NH from Sino Biological Species Human

Human CD33/Siglec-3 Gene ORF cDNA clone expression plasmid - HG12238-UT from Sino Biological Species Human

Human CD33/Siglec-3 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG12238-ACR from Sino Biological Species Human

Human CD33/Siglec-3 Gene ORF cDNA clone expression plasmid, C-His tag - HG12238-CH from Sino Biological Species Human

Human Siglec-3/CD33 (NP_001763) VersaClone cDNA - RDC1477 from R&D Systems Prices $199.00 Sizes 10 µg Species Human

Human CD33 ORF clone (NM_001082618.1) - CDCR044228 from Creative biogene Species Human

Human CD33 ORF clone (NM_001177608.1) - CDCR044230 from Creative biogene Species Human

Human CD33 ORF Clone (BC028152) - CDCS407336 from Creative biogene Species Human Accession C9JEN7

Human CD33 cDNA Clone(NM_001082618.1) - CDFH003096 from Creative biogene Species Human

Human CD33 cDNA Clone(NM_001177608.1) - CDFH003097 from Creative biogene Species Human

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