Gene Symbol | ACADSB |
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Entrez Gene | 36 |
Alt Symbol | 2-MEBCAD, ACAD7, SBCAD |
Species | Human |
Gene Type | protein-coding |
Description | acyl-CoA dehydrogenase, short/branched chain |
Other Description | 2-methyl branched chain acyl-CoA dehydrogenase|2-methylbutyryl-coenzyme A dehydrogenase|acyl-Coenzyme A dehydrogenase, short/branched chain|short/branched chain specific acyl-CoA dehydrogenase, mitochondrial |
Swissprots | Q5SQN6 P45954 Q96CX7 B4DQ51 |
Accessions | AAF97921 EAW49291 P45954 AK298638 BAG60813 AK314241 BAG36909 AL831821 CAD38535 BC013756 AAH13756 BC020931 BC032395 BC045723 BE875638 DA964130 HQ447278 ADQ31765 U12778 AAA74424 NM_001609 NP_001600 |
Function | Has greatest activity toward short branched chain acyl- CoA derivative such as (s)-2-methylbutyryl-CoA, isobutyryl-CoA, and 2-methylhexanoyl-CoA as well as toward short straight chain acyl-CoAs such as butyryl-CoA and hexanoyl-CoA. Can use valproyl- CoA as substrate and may play a role in controlling the metabolic flux of valproic acid in the development of toxicity of this agent. |
Subcellular Location | Mitochondrion matrix. |
Tissue Specificity | Ubiquitous. |
Top Pathways | Fatty acid degradation, Valine, leucine and isoleucine degradation, Fatty acid metabolism |
ACADSB (C-9) - sc-398773 from Santa Cruz Biotechnology
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ACADSB (C-16) - sc-104796 from Santa Cruz Biotechnology
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ACADSB (G-14) - sc-104797 from Santa Cruz Biotechnology
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Anti-ACADSB antibody - ab99951 from Abcam
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Anti-ACADSB antibody - ab154495 from Abcam
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Anti-ACADSB antibody - ab129712 from Abcam
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Anti-ACADSB antibody - ab81644 from Abcam
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Anti-ACADSB Antibody (aa239-273) - LS-C344362 from LifeSpan Bioscience
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Anti-ACADSB Antibody - LS-C153164 from LifeSpan Bioscience
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Anti-ACADSB Antibody - LS-C137306 from LifeSpan Bioscience
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Anti-ACADSB Antibody - LS-C153165 from LifeSpan Bioscience
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Anti-ACADSB Antibody - LS-C332729 from LifeSpan Bioscience
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Anti-ACADSB Antibody (aa254-303) - LS-C81878 from LifeSpan Bioscience
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ACADSB Antibody - NBP1-54788 from Novus Biologicals
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ACADSB Antibody - NBP2-15237 from Novus Biologicals
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Anti-ACADSB (316-330) antibody produced in rabbit - A5109 from Sigma-Aldrich
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Anti-ACADSB antibody produced in rabbit - AV54586 from Sigma-Aldrich
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Anti-ACADSB (396-410) antibody produced in rabbit - A5234 from Sigma-Aldrich
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Valproic Acid Antibody (OAMA00787) - OAMA00787 from Aviva Systems Biology
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Valproic Acid Antibody (OAMA00796) - OAMA00796 from Aviva Systems Biology
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Valproic Acid Antibody (OAMA00815) - OAMA00815 from Aviva Systems Biology
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Valproic Acid Antibody (OAMA00816) - OAMA00816 from Aviva Systems Biology
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ACADSB antibody - middle region (ARP54586_P050) - ARP54586_P050 from Aviva Systems Biology
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ACADSB-Antibody-Center - AP20749c from Abgent, a WuXi AppTec company
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ACADSB-Antibody-Center - AW5336 from Abgent, a WuXi AppTec company
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