Gene Symbol | USP49 |
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Entrez Gene | 25862 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | ubiquitin specific peptidase 49 |
Other Description | deubiquitinating enzyme 49|ubiquitin carboxyl-terminal hydrolase 49|ubiquitin specific protease 49|ubiquitin thioesterase 49|ubiquitin thiolesterase 49|ubiquitin-specific-processing protease 49 |
Swissprots | Q5T3D9 Q5T3E0 Q96CK4 Q70CQ1 |
Accessions | EAX04065 Q70CQ1 AJ586139 CAE51939 AK023682 AL110255 BC014176 AAH14176 BU631853 DN992189 EF565089 JF432543 ADZ15760 NM_001286554 NP_001273483 NM_018561 NP_061031 |
Function | Specifically deubiquitinates histone H2B at 'Lys-120' (H2BK120Ub). H2BK120Ub is a specific tag for epigenetic transcriptional activation and acts as a regulator of mRNA splicing. Deubiquitination is required for efficient cotranscriptional splicing of a large set of exons. {ECO:0000269|PubMed:23824326}. |
Subcellular Location | Nucleus {ECO:0000305|PubMed:23824326}. |
USP49 - MBS1268606 from MyBioSource
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Human USP49 cDNA clone(NM_018561.3) - CDFG001939 from Creative Biomart
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Human USP49 ORF Clone(NM_018561.3) - CDCR303910 from Creative Biomart
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Human USP49 ORF Clone(NM_018561.3) - CDCR303911 from Creative Biomart
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Human USP49 ORF Clone(NM_018561.3) - CDCR303912 from Creative Biomart
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human USP49 ORF clone - CDCH098878 from Creative Biomart
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human USP49 ORF clone - CDCH098879 from Creative Biomart
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Human USP49 ORF Clone(NM_018561.3) - CDCL180719 from Creative Biomart
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Human USP49 Gene ORF cDNA clone expression plasmid - HG12466-G-N from Sino Biological
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human USP49 ORF clone (NM_018561.3) - CDCH098878 from Creative biogene
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Human USP49 ORF Clone (BC014176) - CDCS414818 from Creative biogene
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Human USP49 cDNA Clone(NM_018561.3) - CDFG001939 from Creative biogene
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